RetrogeneDB ID: retro_dmel_70

Retrocopy location

• Organism: Fruit fly (Drosophila melanogaster)
• Coordinates: 2R:11429041..11429782(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: FBgn0022097
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: Vha36-3
• Ensembl ID: FBgn0040377
• Aliases: None
• Description: Vacuolar H[+] ATPase subunit 36-3 [Source:FlyBase gene name;Acc:FBgn0040377]

Sequence

>retro_dmel_70
ATGTCCGGAAAAGATAGGCTACCGATTTTCCCGTCCCGTGGTGCCCAGATGTTGATGAAGGCCCGTCTGGCTGGAGCCCA
GAAAGGTCACGGTCTGCTCAAGAAGAAGGCGGATGCCCTGCAGATGCGATTCCGTTTGATTCTGGGCAAGATCATCGAGA
CCAAGACCCTGATGGGTGATGTTATGAAAGAGGCAGCCTTCTCGCTGGCGGAGGCCAAATTCACGTCTGGCGACATCAAC
CAAGTGGTGCTGCAAAACGTGACCAAGGCCCAGATCAAGATCCGCACCAAGAAGGACAACGTGGCTGGTGTCACTCTGCC
CGTTTTCGAGTCCTACCAGGACGGATCCGACACCTACGAACTGGCCGGTCTAGCCCGTGGTGGTCAGCAGCTGGCCAAGC
TGAAGAAGAACTACCAAAGCGCCGTTAAACTGCTCGTGGAGCTGGCCTCGCTGCAGACCTCATTCGTCACCCTGGACGAG
GTGATCAAGATCACCAACCGTCGTGTGAACGCCATTGAGCATGTGATCATCCCCCGAATCGATAGGACTTTGGCCTACAT
CATCTCGGAGCTGGACGAGCTCGAGCGTGAGGAGTTCTACCGACTGAAGAAGATCCAGGACAAGAAGCGCGAGGCACGCA
TCAAGGCCGACGCCAAGAAGGCGGAGTTGCTGCAGCAGGGCATCGATGTGCGCCAGCAGGCCAATATCCTGGATGAGGGC
GATGACGACGTGCTGTTCTAA

Alignment

ORF - retro_dmel_70 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 83.94 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MAAKDRLPIFPSRGAQTLMKSRLAGATKGHGLLKKKADALQMRFRLILGKIIETKTLMGQVMKEAAFSLA
          M..KDRLPIFPSRGAQ.LMK.RLAGA.KGHGLLKKKADALQMRFRLILGKIIETKTLMG.VMKEAAFSLA
Retrocopy MSGKDRLPIFPSRGAQMLMKARLAGAQKGHGLLKKKADALQMRFRLILGKIIETKTLMGDVMKEAAFSLA

Parental  EVKFTTGDINQIVLQNVTKAQIKIRTKKDNVAGVTLPIFEPYTDGVDTYELAGLARGGQQLAKLKKNYQS
          E.KFT.GDINQ.VLQNVTKAQIKIRTKKDNVAGVTLP.FE.Y.DG.DTYELAGLARGGQQLAKLKKNYQS
Retrocopy EAKFTSGDINQVVLQNVTKAQIKIRTKKDNVAGVTLPVFESYQDGSDTYELAGLARGGQQLAKLKKNYQS

Parental  AVRLLVQLASLQTSFVTLDDVIKVTNRRVNAIEHVIIPRINRTIEYIISELDELEREEFYRLKKIQDKKR
          AV.LLV.LASLQTSFVTLD.VIK.TNRRVNAIEHVIIPRI.RT..YIISELDELEREEFYRLKKIQDKKR
Retrocopy AVKLLVELASLQTSFVTLDEVIKITNRRVNAIEHVIIPRIDRTLAYIISELDELEREEFYRLKKIQDKKR

Parental  EARKASDKLRAEQRLLGQMAEAQEVQNILDEDGDEDLLF
          EAR...D...AE..LL.Q........NILDE.GD.D.LF
Retrocopy EARIKADAKKAE--LLQQGIDVRQQANILDE-GDDDVLF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Drosophila melanogaster was not studied using RNA-Seq expression data.

ChIP-Seq

Drosophila melanogaster was not studied using ChIP-Seq data.

EST

3 EST(s) were mapped to retro_dmel_70 retrocopy

EST ID	Start	End	Identity	Match	Mis-match	Score
CO308693	11429026	11429433	99.6	405	2	403
EC203812	11429026	11429436	99.6	408	2	406
EC226896	11429042	11429419	99.5	375	2	373

TSS

Drosophila melanogaster was not studied using FANTOM5 data.

Lab

retro_dmel_70 was not experimentally validated.

Homology

Retrocopy orthology:

Drosophila melanogaster does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 30 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000008240	1 retrocopy	retro_amel_332,
Bos taurus	ENSBTAG00000016309	2 retrocopies	retro_btau_1757, retro_btau_408,
Canis familiaris	ENSCAFG00000016369	2 retrocopies	retro_cfam_1186, retro_cfam_999,
Choloepus hoffmanni	ENSCHOG00000003733	5 retrocopies	retro_chof_1229, retro_chof_2711, retro_chof_54, retro_chof_926, retro_chof_938,
Cavia porcellus	ENSCPOG00000009085	1 retrocopy	retro_cpor_36,
Felis catus	ENSFCAG00000011078	1 retrocopy	retro_fcat_632,
Myotis lucifugus	ENSMLUG00000006244	5 retrocopies	retro_mluc_2345, retro_mluc_442, retro_mluc_540, retro_mluc_666, retro_mluc_94,
Macaca mulatta	ENSMMUG00000021418	1 retrocopy	retro_mmul_1159,
Monodelphis domestica	ENSMODG00000009896	5 retrocopies	retro_mdom_1196, retro_mdom_1522, retro_mdom_1730, retro_mdom_390, retro_mdom_594,
Mustela putorius furo	ENSMPUG00000007002	2 retrocopies	retro_mputfur_1381, retro_mputfur_748,
Otolemur garnettii	ENSOGAG00000015052	1 retrocopy	retro_ogar_966,
Sus scrofa	ENSSSCG00000002288	1 retrocopy	retro_sscr_357,
Ictidomys tridecemlineatus	ENSSTOG00000027710	1 retrocopy	retro_itri_383,
Vicugna pacos	ENSVPAG00000005696	1 retrocopy	retro_vpac_232,
Drosophila melanogaster	FBgn0040377	1 retrocopy	retro_dmel_70 ,