RetrogeneDB ID: retro_ggor_1507

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 20:28819339..28819873(+)
• Located in intron of: ENSGGOG00000000991

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MCTS1
• Ensembl ID: ENSGGOG00000009420
• Aliases: None
• Description: None

Sequence

>retro_ggor_1507
AAGTTTGATGAAAAGGAAAGTGTGTCCAACTGCATCCAGTTGAAAACGTCAGTTATTAAGGGCATTAAGAGCCAACTGGT
AGAGCAATTTCCAGGTATTGAACCATGGCTTAATCAAATCATGCCTAAGAAAGATCCTGTCAAAATAGTCCGATGCCACG
AACATACAGAAATCCTTACCGTAAGTGGGGAATTACTGTTTTTTAGACAAAGAAAGGGGCCTTTTTGTCCAACTCTAAGG
TTGCTTCACAAATACCCTTTTATCCTGCCACACCAGCAGGTTGATAAAGGAGCTATCAAATTTGTACTCAGTGGCGCAAA
TATTATGTGTCCAGGTTTAACTTCTCCTGGAGCTAAGCTGTACCCTGCTGCGGTAGATACGATTGTAGCAGTCACAGCGG
AAGGAAAACAGCATGCTCTGTGTGTTGGGGTCATGAAGATGTCTGCAGAAGATATTGAGAAAGTCAACAAAGGAATTGGC
ATTGAAAATATCCATTATTTAAATGATGGGCTGTGGCACATGAAGACATATAAA

Alignment

ORF - retro_ggor_1507 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 94.38 %
• Parental protein coverage: 97.8 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  RFDEKENVSNCIQLKTSVIKGIKNQLIEQFPGIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQ
          .FDEKE.VSNCIQLKTSVIKGIK.QL.EQFPGIEPWLNQIMPKKDPVKIVRCHEH.EILTV.GELLFFRQ
Retrocopy KFDEKESVSNCIQLKTSVIKGIKSQLVEQFPGIEPWLNQIMPKKDPVKIVRCHEHTEILTVSGELLFFRQ

Parental  REGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTIVAIMAEGKQHAL
          R.GPF.PTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTIVA..AEGKQHAL
Retrocopy RKGPFCPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTIVAVTAEGKQHAL

Parental  CVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTYK
          CVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTYK
Retrocopy CVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTYK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.91 RPM	5.80 RPM
SRP007412_cerebellum	0.63 RPM	2.36 RPM
SRP007412_heart	0.09 RPM	2.00 RPM
SRP007412_kidney	0.86 RPM	13.45 RPM
SRP007412_liver	0.53 RPM	13.51 RPM
SRP007412_testis	2.59 RPM	6.84 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1507 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1507 has 6 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2422
Pan troglodytes	retro_ptro_1396
Pongo abelii	retro_pabe_1786
Macaca mulatta	retro_mmul_626
Mus musculus	retro_mmus_69
Rattus norvegicus	retro_rnor_1841

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Parental genes homology:

Parental genes homology involve 16 parental genes, and 23 retrocopies.

Species	Parental gene accession	Retrocopies number
Cavia porcellus	ENSCPOG00000005502	1 retrocopy	retro_cpor_1411,
Erinaceus europaeus	ENSEEUG00000007258	1 retrocopy	retro_eeur_197,
Echinops telfairi	ENSETEG00000015462	1 retrocopy	retro_etel_19,
Homo sapiens	ENSG00000232119	1 retrocopy	retro_hsap_2422,
Gorilla gorilla	ENSGGOG00000009420	1 retrocopy	retro_ggor_1507 ,
Myotis lucifugus	ENSMLUG00000015101	1 retrocopy	retro_mluc_16,
Monodelphis domestica	ENSMODG00000010354	1 retrocopy	retro_mdom_203,
Mus musculus	ENSMUSG00000000355	3 retrocopies	retro_mmus_2504, retro_mmus_2505, retro_mmus_69,
Oryctolagus cuniculus	ENSOCUG00000014315	1 retrocopy	retro_ocun_212,
Pan troglodytes	ENSPTRG00000022241	1 retrocopy	retro_ptro_1396,
Pteropus vampyrus	ENSPVAG00000013249	3 retrocopies	retro_pvam_1323, retro_pvam_645, retro_pvam_867,
Rattus norvegicus	ENSRNOG00000002563	2 retrocopies	retro_rnor_1841, retro_rnor_957,
Ictidomys tridecemlineatus	ENSSTOG00000011496	2 retrocopies	retro_itri_1136, retro_itri_1468,
Tupaia belangeri	ENSTBEG00000010666	2 retrocopies	retro_tbel_1485, retro_tbel_4265,
Tarsius syrichta	ENSTSYG00000001440	1 retrocopy	retro_tsyr_55,
Tursiops truncatus	ENSTTRG00000007208	1 retrocopy	retro_ttru_1587,