RetrogeneDB ID: retro_ggor_433

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 1:125947595..125948237(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: SSB
• Ensembl ID: ENSGGOG00000023471
• Aliases: None
• Description: Sjogren syndrome antigen B (autoantigen La) [Source:HGNC Symbol;Acc:11316]

Sequence

>retro_ggor_433
AAAGAAGAAGAAAGAAAACAAAATAAAGTGGAAGCTACATTAAGAGCTAAACAAGAGCAAGAAGCAAATCAAAAGTTGGA
AGAAGATGCTGAAATGAAATCTCTAGAAGAGAAGATTGGATGCTTGCTGAAGTTTTCAGGTGATTTAGATGATCAGACCT
GTAGAGAAGATTTACACATCCTTTTCTCAAGTCATGGTGAAATAAAATGGATAGACTTCATCAGAGGAGCAAAAGAGGGG
ATAATTCTATTTAAAGAAAAAGACAAGGAAGCATTGGGTAAAGCCAAAGATGTAAATAATGGTAATCTACAATTACAGAA
CAAAGAAGTGACTTGGGAAGTACTAGAAGGAGAGGTGGAAAAAGAAGCACTGAAAAAAATAACAGAAGACCAACAAGAAT
CCCTAAACATATGGAAGTCAAAAGGACACAGATTTAAAGGAAAAGGAAAGGGTAATAAAGCTGCCCATCCTAGGTCTGGT
AAAGAAAAAGTACAGTTTCAGGGCAATAAAATGAAATTTGCTAATGATGATGAACATGATGAAAATGGTGCAACTGGACC
TATGAAAAGATCAGGAGAAGAAACAGACAAAGAAGAACCTGTGTCCAAACCACAGAAAAGAGAAAATGGTGCTGGAGACG
AG

Alignment

ORF - retro_ggor_433 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 85.71 %
• Parental protein coverage: 95.59 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  KNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKW
          K.EERKQNKVEA.LRAKQEQEA.QKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFS.HGEIKW
Retrocopy KEEERKQNKVEATLRAKQEQEANQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSSHGEIKW

Parental  IDFVRGAKEGIILFKEKPRKHLGKAKDANNXNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKS
          IDF.RGAKEGIILFKEK....LGKAKD.NN.NLQL.NKEVTWEVLEGEVEKEALKKI.EDQQESLN.WKS
Retrocopy IDFIRGAKEGIILFKEKDKEALGKAKDVNNGNLQLQNKEVTWEVLEGEVEKEALKKITEDQQESLNIWKS

Parental  KGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKT
          KG.RFKGKGKGNKAA.P.SGK.KVQFQG.K.KFA.DDEHDE...NGATGP.KR..EETDKEEP.SK.QK.
Retrocopy KGHRFKGKGKGNKAAHPRSGKEKVQFQGNKMKFANDDEHDE---NGATGPMKRSGEETDKEEPVSKPQKR

Parental  ENGAGDQ
          ENGAGD.
Retrocopy ENGAGDE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	10.98 RPM
SRP007412_cerebellum	0.00 RPM	7.84 RPM
SRP007412_heart	0.00 RPM	2.69 RPM
SRP007412_kidney	0.00 RPM	13.66 RPM
SRP007412_liver	0.11 RPM	5.91 RPM
SRP007412_testis	0.00 RPM	11.60 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_433 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_433 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_448

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 38 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000007763	5 retrocopies	retro_chof_1125, retro_chof_1292, retro_chof_1380, retro_chof_185, retro_chof_2593,
Dasypus novemcinctus	ENSDNOG00000013450	1 retrocopy	retro_dnov_2038,
Echinops telfairi	ENSETEG00000004614	1 retrocopy	retro_etel_2056,
Homo sapiens	ENSG00000138385	1 retrocopy	retro_hsap_448,
Gorilla gorilla	ENSGGOG00000011507	3 retrocopies	retro_ggor_2914, retro_ggor_434, retro_ggor_791,
Gorilla gorilla	ENSGGOG00000023471	4 retrocopies	retro_ggor_2834, retro_ggor_2915, retro_ggor_433 , retro_ggor_792,
Loxodonta africana	ENSLAFG00000000867	3 retrocopies	retro_lafr_698, retro_lafr_745, retro_lafr_982,
Macropus eugenii	ENSMEUG00000001650	1 retrocopy	retro_meug_1908,
Myotis lucifugus	ENSMLUG00000016316	1 retrocopy	retro_mluc_2493,
Macaca mulatta	ENSMMUG00000023051	2 retrocopies	retro_mmul_1153, retro_mmul_529,
Monodelphis domestica	ENSMODG00000008227	1 retrocopy	retro_mdom_1080,
Nomascus leucogenys	ENSNLEG00000004958	3 retrocopies	retro_nleu_1039, retro_nleu_177, retro_nleu_3011,
Otolemur garnettii	ENSOGAG00000029768	1 retrocopy	retro_ogar_1642,
Pongo abelii	ENSPPYG00000012919	3 retrocopies	retro_pabe_3408, retro_pabe_3641, retro_pabe_424,
Pan troglodytes	ENSPTRG00000012620	1 retrocopy	retro_ptro_2509,
Rattus norvegicus	ENSRNOG00000007998	1 retrocopy	retro_rnor_405,
Tupaia belangeri	ENSTBEG00000009056	4 retrocopies	retro_tbel_1065, retro_tbel_1269, retro_tbel_3318, retro_tbel_4012,
Tursiops truncatus	ENSTTRG00000002152	2 retrocopies	retro_ttru_1926, retro_ttru_466,