RetrogeneDB ID: retro_mdom_827

Retrocopy location

• Organism: Opossum (Monodelphis domestica)
• Coordinates: 2:113310014..113310861(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMODG00000002103
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSMODG00000007447
• Aliases: None
• Description: None

Sequence

>retro_mdom_827
ATGCTGAGGCGGACTCTGCAAAACCGGGACGCCCAAACCAAACAGCTGCAGGATGCGGTTTCCAATGTGGAGAAGCACTT
TGGGGAGCTGTGCCAGATCTTCGCGGTGTACGTGTGTAAAACGGCCCCGCTGCGAGACAAAAGCTGACTTCCTGGTGAAT
GAAATCAATGCTTACGCTGCCACCGAGACGCCCAACAAGAAGCACGGCCTGAAGGACTTCGCTGCTAAGTTTGCCAAACA
TCAGGATTATAGGCAAGCTGAGGTTGAAAGACTTGGAGCCAAAGTAGTTAAACCTTTGAAAAGTTATGGAACTATTGTGA
AAATGAAAAGGGATGATCTCAAAGCAACTTTAACAGCAAAGAATCGAGAAGCTAAGCAGTTAACTCAACTGGAAAGGACG
AGTCAACTGTATCCATCAGATCGGCATGTCATATCACAGGCAGAAACAGAATTACAGAGAGCTACAATGGATGCCATCAG
AACAAGTTGGCACCTGGAAGAAACAATTGACAATTTTGAAAAGCAAAGAATAAAGGACATAAAGAATATATTTTCAGAAT
TTATAACTATTGAAATGCTGTTCCATGGTAAAGCTTTAGAAGTCTACACTGTTGCGTGCCAAAATATACAGAAGATTGAT
GAAGAAGATCTAGAGATTTTTCGGAGCTCTCTCTATCCACCTGACTATTCAACTCGTTTAGATATTGTTGGAGCAAATTC
AAAATCTCCTCTTCAGAAATCTGTTTCTATCAAGTGTATATCCGGATGAGGACAGCAGATTCCTACCACTCGGATAAGAA
AAGATCACCAAGATGATGATGAAGAGGATGATGAATTGAACATTACA

Alignment

ORF - retro_mdom_827 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 90.49 %
• Parental protein coverage: 98.61 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MLRRTLENRDAQTKQLQDAVSNVEKHFGELCQIFAAYVRKTARLRDK-ADLLVNEINAYAATETPNLKHG
          MLRRTL.NRDAQTKQLQDAVSNVEKHFGELCQIFA.YV.KTA.LRDK.AD.LVNEINAYAATETPN.KHG
Retrocopy MLRRTLQNRDAQTKQLQDAVSNVEKHFGELCQIFAVYVCKTAPLRDK>ADFLVNEINAYAATETPNKKHG

Parental  LKDFADEFAKLQDYRQAEVERLEAKVVEPLKSYGTIVKMKRDDLKATLTAKSREAKQLTQLERTRQRNPS
          LKDFA..FAK.QDYRQAEVERL.AKVV.PLKSYGTIVKMKRDDLKATLTAK.REAKQLTQLERT.Q..PS
Retrocopy LKDFAAKFAKHQDYRQAEVERLGAKVVKPLKSYGTIVKMKRDDLKATLTAKNREAKQLTQLERTSQLYPS

Parental  DRHVISQAETELQRATMDATRTSRHLEETIDNFEKQKIKDIKNIFSEFITIEMLFHGKALEVYTAAYQNI
          DRHVISQAETELQRATMDA.RTS.HLEETIDNFEKQ.IKDIKNIFSEFITIEMLFHGKALEVYT.A.QNI
Retrocopy DRHVISQAETELQRATMDAIRTSWHLEETIDNFEKQRIKDIKNIFSEFITIEMLFHGKALEVYTVACQNI

Parental  QKIDEEEDLEIFRSSLYPPDYSTRLDIVRANSKSPLQKSISIKCISGSGQQIPTTRIRKDHQDDDEEDDE
          QKID.EEDLEIFRSSLYPPDYSTRLDIV.ANSKSPLQKS.SIKCISG.GQQIPTTRIRKDHQDDDEEDDE
Retrocopy QKID-EEDLEIFRSSLYPPDYSTRLDIVGANSKSPLQKSVSIKCISG*GQQIPTTRIRKDHQDDDEEDDE

Parental  LDVT
          L..T
Retrocopy LNIT

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.00 RPM	0.00 RPM

ChIP-Seq

Monodelphis domestica was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mdom_827 retrocopy.

TSS

Monodelphis domestica was not studied using FANTOM5 data.

Lab

retro_mdom_827 was not experimentally validated.

Homology

Retrocopy orthology:

Monodelphis domestica does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 17 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000009105	1 retrocopy	retro_cfam_1072,
Echinops telfairi	ENSETEG00000013003	1 retrocopy	retro_etel_522,
Homo sapiens	ENSG00000188343	1 retrocopy	retro_hsap_1485,
Gorilla gorilla	ENSGGOG00000006452	1 retrocopy	retro_ggor_1137,
Loxodonta africana	ENSLAFG00000003954	1 retrocopy	retro_lafr_201,
Microcebus murinus	ENSMICG00000006797	1 retrocopy	retro_mmur_415,
Monodelphis domestica	ENSMODG00000007447	2 retrocopies	retro_mdom_1239, retro_mdom_827 ,
Mustela putorius furo	ENSMPUG00000009112	1 retrocopy	retro_mputfur_1183,
Nomascus leucogenys	ENSNLEG00000002773	1 retrocopy	retro_nleu_1707,
Otolemur garnettii	ENSOGAG00000002972	1 retrocopy	retro_ogar_654,
Oreochromis niloticus	ENSONIG00000002446	1 retrocopy	retro_onil_57,
Procavia capensis	ENSPCAG00000011171	1 retrocopy	retro_pcap_272,
Pongo abelii	ENSPPYG00000018744	2 retrocopies	retro_pabe_1235, retro_pabe_2497,
Tarsius syrichta	ENSTSYG00000012502	1 retrocopy	retro_tsyr_975,
Tursiops truncatus	ENSTTRG00000012378	1 retrocopy	retro_ttru_45,