RetrogeneDB ID: retro_ptro_2223

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 5:13392442..13392768(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RPS23
• Ensembl ID: ENSPTRG00000017052
• Aliases: None
• Description: ribosomal protein S23 [Source:HGNC Symbol;Acc:10410]

Sequence

>retro_ptro_2223
AAGAATCTCCCTGTTCACTGACAGGAACATAAGTGGAATGACAAACAGTACAAGAAAGCCCATTTAGGCACAGCCTGAAG
GCCAACGCTTTTGGAAATGCTTCCCATACAAAGAGAACTGTGTTGGAAAAATAGGAGTTGAAGCCGAATGGCCAAATTCT
AATATCAGGAAGTGTACTATAGTTCAGCTGATTGAGAATGGCAAGAAAATCATAGTCTTTGTACCCAACGACGGTTGCTT
GAACTTTATTGAGGAAAAGATGAATTTCTGGTTGCTGAATTGGTCAAAAAGGTCATACTGTTGTTGACATTCCTGTAGTC
TGCTTT

Alignment

ORF - retro_ptro_2223 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 68.42 %
• Parental protein coverage: 82.71 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  RKLRSHRRDQKWHDKQYKKAHLGTA-LKANPFGGASHAKGIVLEK-VGVEAKQPNSAIRKCVRVQLIKNG
          ..L..H....KW.DKQYKKAHLGTA.LKAN.FG.ASH.K..VLEK..GVEA..PNS.IRKC..VQLI.NG
Retrocopy KNLPVH*QEHKWNDKQYKKAHLGTA<LKANAFGNASHTKRTVLEK<IGVEAEWPNSNIRKCTIVQLIENG

Parental  KKITAFVPNDGCLNFIEE-NDEVLVAG-FGRKGHAVGDIPGVRF
          KKI..FVPNDGCLNFIEE..DE.LVA...G.KGH.V.DIP.V.F
Retrocopy KKIIVFVPNDGCLNFIEE<KDEFLVAE<IGQKGHTVVDIPVVCF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	121.96 RPM
SRP007412_cerebellum	0.00 RPM	116.40 RPM
SRP007412_heart	0.00 RPM	97.00 RPM
SRP007412_kidney	0.00 RPM	199.75 RPM
SRP007412_liver	0.00 RPM	137.68 RPM
SRP007412_testis	0.32 RPM	64.39 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_2223 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_2223 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_2223 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3287
Gorilla gorilla	retro_ggor_1316
Pongo abelii	retro_pabe_2716

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Parental genes homology:

Parental genes homology involve 21 parental genes, and 93 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000011136	1 retrocopy	retro_acar_85,
Ailuropoda melanoleuca	ENSAMEG00000015966	3 retrocopies	retro_amel_1096, retro_amel_341, retro_amel_751,
Bos taurus	ENSBTAG00000013358	3 retrocopies	retro_btau_173, retro_btau_205, retro_btau_80,
Callithrix jacchus	ENSCJAG00000011247	2 retrocopies	retro_cjac_126, retro_cjac_256,
Cavia porcellus	ENSCPOG00000022705	2 retrocopies	retro_cpor_1182, retro_cpor_1377,
Equus caballus	ENSECAG00000020523	2 retrocopies	retro_ecab_275, retro_ecab_500,
Erinaceus europaeus	ENSEEUG00000001849	7 retrocopies	retro_eeur_102, retro_eeur_262, retro_eeur_326, retro_eeur_462, retro_eeur_515, retro_eeur_53, retro_eeur_662,
Felis catus	ENSFCAG00000008839	7 retrocopies	retro_fcat_1557, retro_fcat_1601, retro_fcat_1876, retro_fcat_2000, retro_fcat_5, retro_fcat_609, retro_fcat_644,
Loxodonta africana	ENSLAFG00000031506	3 retrocopies	retro_lafr_1117, retro_lafr_1216, retro_lafr_606,
Microcebus murinus	ENSMICG00000013964	2 retrocopies	retro_mmur_1354, retro_mmur_872,
Myotis lucifugus	ENSMLUG00000013939	2 retrocopies	retro_mluc_1676, retro_mluc_2183,
Macaca mulatta	ENSMMUG00000003578	4 retrocopies	retro_mmul_1239, retro_mmul_1974, retro_mmul_2305, retro_mmul_852,
Oryctolagus cuniculus	ENSOCUG00000010363	2 retrocopies	retro_ocun_195, retro_ocun_95,
Otolemur garnettii	ENSOGAG00000008163	11 retrocopies	retro_ogar_1177, retro_ogar_1303, retro_ogar_1785, retro_ogar_1849, retro_ogar_238, retro_ogar_2479, retro_ogar_253, retro_ogar_2695, retro_ogar_2823, retro_ogar_3519, retro_ogar_364,
Pan troglodytes	ENSPTRG00000017052	6 retrocopies	retro_ptro_1190, retro_ptro_2056, retro_ptro_2223 , retro_ptro_2707, retro_ptro_3075, retro_ptro_3122,
Rattus norvegicus	ENSRNOG00000016580	12 retrocopies	retro_rnor_100, retro_rnor_1394, retro_rnor_149, retro_rnor_1691, retro_rnor_1941, retro_rnor_1959, retro_rnor_1982, retro_rnor_2119, retro_rnor_2182, retro_rnor_2492, retro_rnor_525, retro_rnor_559,
Sorex araneus	ENSSARG00000008904	8 retrocopies	retro_sara_194, retro_sara_346, retro_sara_422, retro_sara_481, retro_sara_540, retro_sara_647, retro_sara_648, retro_sara_714,
Sarcophilus harrisii	ENSSHAG00000008347	2 retrocopies	retro_shar_257, retro_shar_348,
Ictidomys tridecemlineatus	ENSSTOG00000000824	3 retrocopies	retro_itri_1418, retro_itri_204, retro_itri_377,
Tarsius syrichta	ENSTSYG00000011385	5 retrocopies	retro_tsyr_1656, retro_tsyr_1946, retro_tsyr_406, retro_tsyr_462, retro_tsyr_933,
Tursiops truncatus	ENSTTRG00000014491	6 retrocopies	retro_ttru_1253, retro_ttru_1555, retro_ttru_186, retro_ttru_458, retro_ttru_487, retro_ttru_578,