ABOUT THIS RECORDspecies: Mus musculus
miRNA family: mir-154
source: miRBase, original name: mmu-mir-410 (MI0001161)
Taxonomy by NCBI:
Mus musculus Mus Mus Murinae Muridae Muroidea Sciurognathi Rodentia Glires Euarchontoglires Eutheria Theria Mammalia Amniota Tetrapoda Sarcopterygii Euteleostomi Teleostomi Gnathostomata Vertebrata Craniata Chordata Deuterostomia Coelomata Bilateria Eumetazoa Metazoa Fungi/Metazoa group Eukaryota cellular organisms
SEQUENCE & STRUCTURE| miRNA AATATAACACAGATGGCCTGT miRNA* AGGTTGTCTGTGATGAGTTCG mismatches: 5 bulges: 0 |
pre-miRNA
GGGTACTTGAGGAGAGGTTGTCTGTGATGAGTTCGCTTTATTAATGACGAATATAACACAGATGGCCTGTTTTCAATACCA
dot-bracket secondary structure
.((((.(((((((.((((..((((((.((.((((((.........).))))).)).))))))..)))).))))))))))).
SIMILARITIES
MORE
miRNEST target predictions: none
non-miRNEST targets
HuntMi prediction: true miRNA
additional data
download this record
evidence: Northern, PCR, cloned, insitu
deep sequencing data evidence
references
[1] Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP, Genes Dev. 24:992-1009(2010)., "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes"
[2] Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M, Cell. 129:1401-1414(2007)., "A mammalian microRNA expression atlas based on small RNA library sequencing"
[3] Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H, J Virol. 84:10266-10275(2010)., "Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68"
[4] Seitz H, Royo H, Bortolin ML, Lin SP, Ferguson-Smith AC, Cavaille J, Genome Res. 14:1741-1748(2004)., "A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain"
[5] Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M, BMC Bioinformatics. 6:267(2005)., "Identification of clustered microRNAs using an ab initio prediction method"
[6] Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A, Mol Hum Reprod. 16:463-471(2010)., "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing"
[7] Wheeler G, Ntounia-Fousara S, Granda B, Rathjen T, Dalmay T, FEBS Lett. 580:2195-2200(2006)., "Identification of new central nervous system specific mouse microRNAs"
GGGTACTTGAGGAGAGGTTGTCTGTGATGAGTTCGCTTTATTAATGACGAATATAACACAGATGGCCTGTTTTCAATACCA
dot-bracket secondary structure
.((((.(((((((.((((..((((((.((.((((((.........).))))).)).))))))..)))).))))))))))).
SIMILARITIES| miRBase bta-mir-410: 2e-38 PMRD no hits microPC no hits | UniProt no hits RFAM mir-154: 9e-29 |
Identical with: rno-mir-410 from miRBase (MNEST032904) |
MOREmiRNEST target predictions: none
non-miRNEST targets
HuntMi prediction: true miRNA
additional data
download this record
evidence: Northern, PCR, cloned, insitu
deep sequencing data evidence
references
[1] Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP, Genes Dev. 24:992-1009(2010)., "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes"
[2] Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M, Cell. 129:1401-1414(2007)., "A mammalian microRNA expression atlas based on small RNA library sequencing"
[3] Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H, J Virol. 84:10266-10275(2010)., "Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68"
[4] Seitz H, Royo H, Bortolin ML, Lin SP, Ferguson-Smith AC, Cavaille J, Genome Res. 14:1741-1748(2004)., "A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain"
[5] Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M, BMC Bioinformatics. 6:267(2005)., "Identification of clustered microRNAs using an ab initio prediction method"
[6] Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A, Mol Hum Reprod. 16:463-471(2010)., "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing"
[7] Wheeler G, Ntounia-Fousara S, Granda B, Rathjen T, Dalmay T, FEBS Lett. 580:2195-2200(2006)., "Identification of new central nervous system specific mouse microRNAs"
