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Species belonging to selected taxon:

Drosophila melanogaster, Drosophila simulans, Glossina morsitans morsitans, Drosophila sechellia, Drosophila auraria, Drosophila pseudoobscura, Teleopsis dalmanni, Drosophila willistoni, Drosophila ananassae, Drosophila virilis, Drosophila erecta, Drosophila grimshawi, Ceratitis capitata, Drosophila mojavensis, Cochliomyia hominivorax, Haematobia irritans irritans, Drosophila yakuba



ABOUT THIS RECORD

ID: MNEST036374
species: Drosophila melanogaster
miRNA family: mir-34
source: miRBase, original name: dme-mir-34 (MI0000371)

Taxonomy by NCBI:
Drosophila melanogaster melanogaster subgroup melanogaster group Sophophora Drosophila Drosophiliti Drosophilina Drosophilini Drosophilinae Drosophilidae Ephydroidea Acalyptratae Schizophora Cyclorrhapha Eremoneura Muscomorpha Brachycera Diptera Endopterygota Neoptera Pterygota Dicondylia Insecta Hexapoda Pancrustacea Mandibulata Arthropoda Panarthropoda Protostomia Coelomata Bilateria Eumetazoa Metazoa Fungi/Metazoa group Eukaryota cellular organisms






SEQUENCE & STRUCTURE
miRNA
CAGCCACTATCTTCACTGCCGCC

miRNA*
TGGCAGTGTGGTTAGCTGGTTGTG

mismatches: 4
bulges: 1

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pre-miRNA
AATTGGCTATGCGCTTTGGCAGTGTGGTTAGCTGGTTGTGTAGCCAATTATTGCCGTTGACAATTCACAGCCACTATCTTCACTGCCGCCGCGACAAGC

dot-bracket secondary structure
.....(((.(((((..((((((((.((.(((.((((((((..(.((((.......)))).)....))))))))))).)).))))))))..))).)))))


SIMILARITIES
miRBase dme-mir-34: 2e-51

PMRD no hits

microPC no hits
UniProt no hits

RFAM mir-449: 1e-49

Identical with: dse-mir-34 from miRBase (MNEST037139)

MORE

miRNEST target predictions: none
non-miRNEST targets: none
HuntMi prediction: true miRNA
additional data
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references

[1] Lai EC, Tomancak P, Williams RW, Rubin GM, Genome Biol. 4:R42(2003)., "Computational identification of Drosophila microRNA genes"
[2] Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T, Dev Cell. 5:337-350(2003)., "The small RNA profile during Drosophila melanogaster development"
[3] Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V, Dev Biol. 259:9-18(2003)., "Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity"
[4] Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC, Genome Res. 17:1850-1864(2007)., "Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs"
[5] Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis M, Genome Res. 17:1865-1879(2007)., "Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes"




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