RetrogeneDB ID: retro_chof_2392

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_70993:7795..8655(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCHOG00000007548
• Aliases: None
• Description: None

Sequence

>retro_chof_2392
AATGAAGAAGGTTGGAGGAGAGCAGTGTGGGAGAAGAATTTGAAAATGATTGAACTGCACAATCTGGAATACAGCCTGGG
CAATATAGCTTAAAGACCAGAATGAATGCCTTTGGTGACATGACCAATGAAGAATTCAAGCAGGTGATGAATGGCTTTCA
AAACCAGGAACACAAGGAGGGGAAAATGTTCTATAAACTTCCCTCTGAGGTTCACAAATCTGTGGATTGGCATAAGAAAG
ATTACATGTCTCCCGTGAAGAATCAGCATCAGTGTGGTTCTTGTTGGGCTTTCAGTGCAATCGGTTCCCTGGAAGGACAG
ATATTCCAGAAAACTGGCAAACTTGTTTCACTTGGTGAGCAGAACCTGGCAGACTGCTCTCAGGCTGAAGGCAATAACAG
CTGCAATGGCGGCCTAATGGACAATGCTTTCCAGTATGTCCAGGACAACAAAGGCCTTGATTCACAGAAATCCTACCCAT
ATATTGGAAAGTACATGACCTGTTGCTACAAGCCCAAGTATTCTGCTGTCAATGACACTGGCTTTGTGGACATCCCTCCA
TGGGAAAAGGCACTTATGAAGGCAGTGGCAACTATAGGTCCCATCTCAGTTGCTATTGATGCAAGCTATGACTCCTTCAA
GTTCTACTCATCAGGCATTTATTAGCCAGATGGCAGCAGTAAAGACCTAGATCATGGTGTCCTGGTGGTCAACTGTGGCT
TTGAAGAAACAGATTCAGATAACAATAAATACTGGCTTGTGAGGAACAGCTGGGGTGAAGATTGGGGCATGGAGGGCAAA
ATAAAGATGGCCAGAGACCAGAACGACCGCTGTGGAGTTGCCACCTCAGCCAGCTATCCC

Alignment

ORF - retro_chof_2392 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 75.09 %
• Parental protein coverage: 91.72 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  SEEDWRRAVWEKNMKIIEVHNQEYSLG-QHSFKLGMNAFGDMTSEEFRQVMNGFQNKEHKKGEMFSESPS
          .EE.WRRAVWEKN.K.IE.HN.EYSLG.Q.S.K..MNAFGDMT.EEF.QVMNGFQN.EHK.G.MF...PS
Retrocopy NEEGWRRAVWEKNLKMIELHNLEYSLG<QYSLKTRMNAFGDMTNEEFKQVMNGFQNQEHKEGKMFYKLPS

Parental  EVPTSVDWRDKGYVTPVKNQGHCGSCWAFSAAGSLEGQMFRKTGILVSLSEQNLVDCSRAEGNSGCNGGL
          EV..SVDW..K.Y..PVKNQ..CGSCWAFSA.GSLEGQ.F.KTG.LVSL.EQNL.DCS.AEGN..CNGGL
Retrocopy EVHKSVDWHKKDYMSPVKNQHQCGSCWAFSAIGSLEGQIFQKTGKLVSLGEQNLADCSQAEGNNSCNGGL

Parental  MDNAFQYVQDNKGLDSEESYPYVGKDMNCSYKPEYSAANDTGFVEVAPLEKTLMAAVAAVGPISVAIDAS
          MDNAFQYVQDNKGLDS..SYPY.GK.M.C.YKP.YSA.NDTGFV...P.EK.LM.AVA..GPISVAIDAS
Retrocopy MDNAFQYVQDNKGLDSQKSYPYIGKYMTCCYKPKYSAVNDTGFVDIPPWEKALMKAVATIGPISVAIDAS

Parental  HESFQFYESGIYYEPDCSSKDLDHGVLVVGYGFEETDSDNNKYWLVKNSWGESWGMEGYVKMARDRDNHC
          ..SF.FY.SGI.Y.PD.SSKDLDHGVLVV..GFEETDSDNNKYWLV.NSWGE.WGMEG..KMARD....C
Retrocopy YDSFKFYSSGI-Y*PDGSSKDLDHGVLVVNCGFEETDSDNNKYWLVRNSWGEDWGMEGKIKMARDQNDRC

Parental  GIATKASYP
          G.AT.ASYP
Retrocopy GVATSASYP

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_2392 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 10 parental genes, and 21 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000007548	8 retrocopies	retro_chof_1227, retro_chof_1332, retro_chof_1345, retro_chof_141, retro_chof_1464, retro_chof_2392 , retro_chof_383, retro_chof_424,
Dasypus novemcinctus	ENSDNOG00000012037	1 retrocopy	retro_dnov_2387,
Macropus eugenii	ENSMEUG00000002168	2 retrocopies	retro_meug_1349, retro_meug_1567,
Macropus eugenii	ENSMEUG00000014293	1 retrocopy	retro_meug_1873,
Macropus eugenii	ENSMEUG00000016209	2 retrocopies	retro_meug_159, retro_meug_1727,
Monodelphis domestica	ENSMODG00000002844	1 retrocopy	retro_mdom_1101,
Otolemur garnettii	ENSOGAG00000001349	2 retrocopies	retro_ogar_1053, retro_ogar_1373,
Ochotona princeps	ENSOPRG00000001030	2 retrocopies	retro_opri_186, retro_opri_499,
Petromyzon marinus	ENSPMAG00000003453	1 retrocopy	retro_pmar_7,
Tupaia belangeri	ENSTBEG00000016406	1 retrocopy	retro_tbel_2841,