RetrogeneDB ID: retro_fcat_75

Retrocopy location

• Organism: Cat (Felis catus)
• Coordinates: X:83182108..83182975(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSFCAG00000013517
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: MORF4L1
• Ensembl ID: ENSFCAG00000012197
• Aliases: None
• Description: mortality factor 4 like 1 [Source:HGNC Symbol;Acc:16989]

Sequence

>retro_fcat_75
ATGAGTTCCAGAAAGCAGGGTTCTCAAACTCGTGGACAACAATCTGCAGAAGAAGACAACTTCAAAAAACCAAGTAGAAG
CAATATGCAGAGAAGTAAGATGAGAGGGGCCTCTTCAGGAAAGAAGACTGCTGGTTCACAGCAGAAGAATGTGGAACCAG
CTCTCCCAGGCAGATGGGGGGGTCGCTCTGCAGAGAACCCCCCTTCAGGATCAGTGAGGAAGACAAGAAAGAACAAACAG
AAGACTCCTGGAAATGGAGATGGTGGCAGTACCAGCGAAGCACCTCAGCCACCTCGGAAGAAAAGGGCCCGGGCAGACCC
CACTGTCGAAAGTGAGGAGGCATTTAAGAATAGAATGGAAGTTAAAGTGAAGATTCCTGAAGAATTAAAACCATGGCTTG
TTGAGGACTGGGACTTAGTTACCAGGCAGAAGCAGCTGTTTCAACTCCCTGCTAAGAAAAATGTAGATGCTATTCTGGAG
GAGTACGCAAATTGTAAGAAGTCGCAGGGAAATGTTGATAATAAGGAATATGCAGTTAATGAAGTTGTGGCAGGAATAAA
AGAATATTTCAATGTGATGTTGGGCACTCAGCTGCTCTACAAATTTGAGAGGCCCCAGTATGCCGAAATCCTCTTGGCTC
ACCCTGATGCGCCAATGTCCCAGGTTTATGGAGCCCCACATCTACTGAGATTATTTGTAAGAATCGGAGCAATGTTGGCG
TATACGCCCCTTGATGAGAAGAGCCTTGCATTATTGTTGGGCTATTTGCATGATTTCCTAAAATATCTGGCAAAGAATGC
TGCGTCTCTGTTTACTGCCAGTGATTACAAAGTGGCTTCAGCTGAGTACCACCGCAAAGCCCTGTGA

Alignment

ORF - retro_fcat_75 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 80.33 %
• Parental protein coverage: 69.91 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  NQEQYAEGKMRGAAPGKKTAGLQQKSVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVDPTVENEET
          .Q....E....G...G.........SV..KT.KNKQKTPGNGDGGSTSE.PQPPRKKRAR.DPTVE.EE.
Retrocopy SQQKNVEPALPGRWGGRSAENPPSGSVR-KTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEA

Parental  FMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVA
          F.NR.EVKVKIPEELKPWLV.DWDL.TRQKQLF.LPAKKNVD.ILE.YAN.KKS.GN.DNKEYAVNEVVA
Retrocopy FKNRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEYANCKKSQGNVDNKEYAVNEVVA

Parental  GIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLN
          GIKEYFNVMLGTQLLYKFERPQYAEIL..HPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLL.
Retrocopy GIKEYFNVMLGTQLLYKFERPQYAEILLAHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLG

Parental  YLHDFLKYLAKNSATLFSASDYEVAPPEYHRKAV
          YLHDFLKYLAKN.A.LF.ASDY.VA..EYHRKA.
Retrocopy YLHDFLKYLAKNAASLFTASDYKVASAEYHRKAL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	61.40 RPM	109.49 RPM
SRP017611_kidney	39.88 RPM	97.49 RPM
SRP017611_liver	48.52 RPM	41.85 RPM

ChIP-Seq

Felis catus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_fcat_75 retrocopy.

TSS

Felis catus was not studied using FANTOM5 data.

Lab

retro_fcat_75 was not experimentally validated.

Homology

Retrocopy orthology:

Felis catus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 17 parental genes, and 37 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000010988	1 retrocopy	retro_btau_137,
Canis familiaris	ENSCAFG00000014113	1 retrocopy	retro_cfam_20,
Callithrix jacchus	ENSCJAG00000002214	5 retrocopies	retro_cjac_2113, retro_cjac_2280, retro_cjac_2574, retro_cjac_3026, retro_cjac_3179,
Cavia porcellus	ENSCPOG00000003778	3 retrocopies	retro_cpor_114, retro_cpor_1409, retro_cpor_915,
Equus caballus	ENSECAG00000008091	1 retrocopy	retro_ecab_62,
Felis catus	ENSFCAG00000012197	1 retrocopy	retro_fcat_75 ,
Loxodonta africana	ENSLAFG00000009851	1 retrocopy	retro_lafr_62,
Myotis lucifugus	ENSMLUG00000001756	1 retrocopy	retro_mluc_324,
Monodelphis domestica	ENSMODG00000011517	2 retrocopies	retro_mdom_150, retro_mdom_158,
Oryctolagus cuniculus	ENSOCUG00000015117	2 retrocopies	retro_ocun_108, retro_ocun_21,
Otolemur garnettii	ENSOGAG00000006047	4 retrocopies	retro_ogar_1594, retro_ogar_2616, retro_ogar_2896, retro_ogar_50,
Sorex araneus	ENSSARG00000004519	1 retrocopy	retro_sara_15,
Sarcophilus harrisii	ENSSHAG00000018402	1 retrocopy	retro_shar_393,
Ictidomys tridecemlineatus	ENSSTOG00000013294	3 retrocopies	retro_itri_111, retro_itri_1545, retro_itri_1608,
Tupaia belangeri	ENSTBEG00000001897	8 retrocopies	retro_tbel_1694, retro_tbel_1704, retro_tbel_4638, retro_tbel_518, retro_tbel_550, retro_tbel_69, retro_tbel_753, retro_tbel_76,
Tursiops truncatus	ENSTTRG00000016606	1 retrocopy	retro_ttru_472,
Vicugna pacos	ENSVPAG00000008847	1 retrocopy	retro_vpac_229,