RetrogeneDB ID: retro_ggor_1869

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 3:95783976..95784499(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000025402
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: CDV3
• Ensembl ID: ENSGGOG00000027821
• Aliases: None
• Description: None

Sequence

>retro_ggor_1869
GAAGAATGGAAAGGCTTGGAGTAAAAAGAGGTTGATTACAGAGGCCTGGGGGTTCAGGCAATGCAAATAAGTGAAAAGGA
AGACGATATTGAAGAGACAAGATCCAGGTGATAACTGGGAAGAAGGCGGAGGTGGTGGTGATACAGAAAAATCTTCAGGT
CCCTGGAATAAAACAGCTCTGGTACAAGCACCTCTTGCTCCAGTAATTGTTACAGAAACCCCAGAACTGGCAATGACTAG
TGGTGTGTGTGTGTGTAGGCCTCCTGGGGCCAGGTTAACCACAACAAGGAAAGCACCACAAGGACCACCAGAAATCTACA
GCAATACACAGTTCCCATCCCTGCAGTCAACTGCCAAGCACATAGAAAGCCTGAAGGATAAAGAAATGGAGAAGAGCTTT
CAAGTAATAAGACACAAAAGTAGAGGTAGGGATGAAGTTTCAAAAAACCAGGCCCTTAAACTTCAGCCAGACAACCGGTA
TGCTGTGCTTGAAAATCAGAAAAGGAGTCACTCACAATACAAT

Alignment

ORF - retro_ggor_1869 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 81.01 %
• Parental protein coverage: 98.88 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  DEWKELEQKEVDYSGLRVQAMQISSEKEEDDNE-KRQDPGDNWEEGGGGGGGMEKSSGPWNKTAPVQAPP
          .EWK.LE.KEVDY.GL.VQAMQIS...E..D...KRQDPGDNWEEGGGGG...EKSSGPWNKTA.VQAP.
Retrocopy EEWKGLE*KEVDYRGLGVQAMQIS---EKEDDI>KRQDPGDNWEEGGGGGD-TEKSSGPWNKTALVQAPL

Parental  APVIVTETPEPAMTS--GVYRPPGARLTTTRKTPQGPPEIYSDTQFPSLQSTAKHVESRKDKEMEKSFEV
          APVIVTETPE.AMTS.....RPPGARLTTTRK.PQGPPEIYS.TQFPSLQSTAKH.ES.KDKEMEKSF.V
Retrocopy APVIVTETPELAMTSXXXXXRPPGARLTTTRKAPQGPPEIYSNTQFPSLQSTAKHIESLKDKEMEKSFQV

Parental  VRHKNRGRDEVSKNQALKLQLDNQYAVLENQKSSHSQYN
          .RHK.RGRDEVSKNQALKLQ.DN.YAVLENQK.SHSQYN
Retrocopy IRHKSRGRDEVSKNQALKLQPDNRYAVLENQKRSHSQYN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	76.63 RPM
SRP007412_cerebellum	0.00 RPM	42.35 RPM
SRP007412_heart	0.00 RPM	35.93 RPM
SRP007412_kidney	0.00 RPM	105.70 RPM
SRP007412_liver	0.00 RPM	76.29 RPM
SRP007412_testis	0.10 RPM	196.11 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1869 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1869 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2678
Pan troglodytes	retro_ptro_1805

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Parental genes homology:

Parental genes homology involve 14 parental genes, and 38 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000035556	1 retrocopy	retro_btau_253,
Choloepus hoffmanni	ENSCHOG00000008963	5 retrocopies	retro_chof_1355, retro_chof_1701, retro_chof_1763, retro_chof_2308, retro_chof_818,
Callithrix jacchus	ENSCJAG00000002998	1 retrocopy	retro_cjac_2928,
Dasypus novemcinctus	ENSDNOG00000010208	5 retrocopies	retro_dnov_2359, retro_dnov_2616, retro_dnov_460, retro_dnov_496, retro_dnov_656,
Equus caballus	ENSECAG00000015689	2 retrocopies	retro_ecab_444, retro_ecab_636,
Homo sapiens	ENSG00000091527	1 retrocopy	retro_hsap_2678,
Gorilla gorilla	ENSGGOG00000027821	1 retrocopy	retro_ggor_1869 ,
Myotis lucifugus	ENSMLUG00000009864	1 retrocopy	retro_mluc_1296,
Mus musculus	ENSMUSG00000032803	10 retrocopies	retro_mmus_1266, retro_mmus_2405, retro_mmus_2408, retro_mmus_2411, retro_mmus_2412, retro_mmus_2416, retro_mmus_2418, retro_mmus_2422, retro_mmus_2423, retro_mmus_2534,
Ochotona princeps	ENSOPRG00000003600	3 retrocopies	retro_opri_1017, retro_opri_739, retro_opri_740,
Pongo abelii	ENSPPYG00000025898	1 retrocopy	retro_pabe_2301,
Pan troglodytes	ENSPTRG00000015409	1 retrocopy	retro_ptro_1805,
Sus scrofa	ENSSSCG00000011637	1 retrocopy	retro_sscr_701,
Tupaia belangeri	ENSTBEG00000014910	5 retrocopies	retro_tbel_2284, retro_tbel_2443, retro_tbel_4022, retro_tbel_4157, retro_tbel_4378,