RetrogeneDB ID: retro_ggor_759

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 11:122976413..122976864(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RNF181
• Ensembl ID: ENSGGOG00000004953
• Aliases: None
• Description: None

Sequence

>retro_ggor_759
ATGACAGCCTATTTCAATGAACAAGACTGCAAGCTCTTGAACCCCAAGCAGGAGACCCTAACCCACATACTGCTGGAGCT
CACCAGATCACTTTTCAATAGGATGGATTTTGAAGACTCGGGGATGGCAGTAAATTGGAATCACCACCTGCCTCCACCAG
CTGCCAAGACAGTGTGGTTGGGAACCTCCCCAGGACAGTCATCAGGAGCTCTCAGGCTGAGAGACACACACAAGTGCCCC
ATGTGCTTGAGGAGGAGGAGGCTGTTGTTGGGATGCCTTGCCATTAGCTTTTCCATTCTAACTGCATTTTGCCCCGGCTA
AGCAAGACAAATCCCTGTCCCTTGTGCTGCCAGGAGCTGCCCGCTGATAACGACACTTGTGAGGAGCACAGAGGAGATAA
GGCTCGAAACAGCAGCAGCAGCACTGTCTGGAGAACCTCTACAGAGCCATG

Alignment

ORF - retro_ggor_759 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 65.58 %
• Parental protein coverage: 98.69 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MASYFDEHDCEPSDPEQETRTNMLLELARSLFNRMDFEDLGLVVDWDHHLP-PPAAK-TVVENLPRTVIR
          M..YF.E.DC....P.QET.T..LLEL.RSLFNRMDFED.G..V.W.HHLP.P.A....VV.NLPRTVIR
Retrocopy MTAYFNEQDCKLLNPKQETLTHILLELTRSLFNRMDFEDSGMAVNWNHHLPPPAAKT<SVVGNLPRTVIR

Parental  GSQAELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTNSCPLCRHELPTDDDTYEEHRRDKAR-K
          .SQAE....V.....EEEE....MPCH.LFHS.CILP.LSKTN.CPLC..ELP.D.DT.EEHR.DKAR.K
Retrocopy SSQAERHTQVPHV-LEEEEAVVGMPCH*LFHSNCILPRLSKTNPCPLCCQELPADNDTCEEHRGDKAR<K

Parental  QQQQHRLENLHGAM
          QQQQH.LENL..AM
Retrocopy QQQQHCLENLYRAM

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.43 RPM	25.13 RPM
SRP007412_cerebellum	0.20 RPM	18.83 RPM
SRP007412_heart	0.13 RPM	12.95 RPM
SRP007412_kidney	0.29 RPM	60.72 RPM
SRP007412_liver	0.34 RPM	35.74 RPM
SRP007412_testis	1.14 RPM	63.30 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_759 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_759 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_938
Pan troglodytes	retro_ptro_650
Pongo abelii	retro_pabe_807
Macaca mulatta	retro_mmul_1128

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Parental genes homology:

Parental genes homology involve 3 parental genes, and 8 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000019647	3 retrocopies	retro_cjac_2423, retro_cjac_355, retro_cjac_3849,
Gorilla gorilla	ENSGGOG00000004953	3 retrocopies	retro_ggor_2537, retro_ggor_759 , retro_ggor_799,
Pongo abelii	ENSPPYG00000012225	2 retrocopies	retro_pabe_3083, retro_pabe_807,