RetrogeneDB ID: retro_mmul_253

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 12:2922081..2922723(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMMUG00000013925
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: MMU.1726
• Ensembl ID: ENSMMUG00000015504
• Aliases: None
• Description: ATP synthase subunit O, mitochondrial [Source:RefSeq peptide;Acc:NP_001182512]

Sequence

>retro_mmul_253
ATGGCCGCCCCAGCAGTGTCCGGGCTCTCCCGGCAGGTGCGATGCTTCAGTACCTCTGTGGTCAGACCATTTGCCAAGCT
TGTGAGGCCTCCTGTTCAGGTATACAGTATTGAAGGTCGCTATGCCACAGCTCTTTATTCTGCTGCATCAAAACAGAGTA
AGTTGGAGGAAGTAGAAAAGGAGTTGTTGAGAGTAGCACAAATCCTGAAGGAACCCAAAGTGGCTGCTTCTGTTTTGAAT
CCCTATGTGAAGCGTTCTGTTAGAGTGAAAAGCCTAAAGGACATCACAGCAAAAGAGAGGTTCTCTCCCGTCACCACCAA
CTGGATCAATGTGCTTGCTGAAAATGGTCGCTTAAGCAATACCCAAGGAGTCGTTTCTGCCTTTTTTACCATGATGAGTG
TCCATCGCGGAGAGGTACCTTGCACAGTGACCACTGCATCTCCTTTAGAAGAAGCCATACTCTCTGAATTAAAAACTGTC
CTCAAGAGCTTCGTAAGTCAAGGCCAAGTATTGAAATTGGAGGCTAAGACTGATCTGTCAATCACGGGTGGAATGACTGT
GCGCATTGGAGAGAAATATGTTGGCACGTCTGTCAAGACCAAGATTCAGAAGCTGGGCAGGGCTATGTGGGAGGTTGTCT
AA

Alignment

ORF - retro_mmul_253 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.67 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MAAPGVSGLSRQVRCFSTSVVRPFAKLVRPPVQVYGIEGRYATALYSAASKQNKLEQVEKELLRVAQILK
          MAAP.VSGLSRQVRCFSTSVVRPFAKLVRPPVQVY.IEGRYATALYSAASKQ.KLE.VEKELLRVAQILK
Retrocopy MAAPAVSGLSRQVRCFSTSVVRPFAKLVRPPVQVYSIEGRYATALYSAASKQSKLEEVEKELLRVAQILK

Parental  EPKVAASVLNPYVKRSIKVKSLNDITAKERFSPLTTNLINLLAENGRLSNAQGVVSAFSTMMSVHRGEVP
          EPKVAASVLNPYVKRS..VKSL.DITAKERFSP.TTN.IN.LAENGRLSN.QGVVSAF.TMMSVHRGEVP
Retrocopy EPKVAASVLNPYVKRSVRVKSLKDITAKERFSPVTTNWINVLAENGRLSNTQGVVSAFFTMMSVHRGEVP

Parental  CTVTTASPLEEATLSELKTVLKSFLSQGQVLKLEAKTDPSIMGGMIVRIGEKYVDMSVRTKIQKLGRAMR
          CTVTTASPLEEA.LSELKTVLKSF.SQGQVLKLEAKTD.SI.GGM.VRIGEKYV..SV.TKIQKLGRAM.
Retrocopy CTVTTASPLEEAILSELKTVLKSFVSQGQVLKLEAKTDLSITGGMTVRIGEKYVGTSVKTKIQKLGRAMW

Parental  EAV
          E.V
Retrocopy EVV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	101.52 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	109.79 RPM
SRP007412_cerebellum	0.06 RPM	85.63 RPM
SRP007412_heart	0.00 RPM	222.94 RPM
SRP007412_kidney	0.12 RPM	149.41 RPM
SRP007412_liver	0.08 RPM	66.70 RPM
SRP007412_testis	0.04 RPM	92.27 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_253 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_253 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_253 has 0 orthologous retrocopies within eutheria group .

---

Parental genes homology:

Parental genes homology involve 22 parental genes, and 47 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000014708	1 retrocopy	retro_amel_1914,
Canis familiaris	ENSCAFG00000009541	3 retrocopies	retro_cfam_1277, retro_cfam_2198, retro_cfam_235,
Choloepus hoffmanni	ENSCHOG00000011242	1 retrocopy	retro_chof_638,
Callithrix jacchus	ENSCJAG00000002873	1 retrocopy	retro_cjac_1567,
Equus caballus	ENSECAG00000009059	1 retrocopy	retro_ecab_633,
Echinops telfairi	ENSETEG00000000807	5 retrocopies	retro_etel_1412, retro_etel_1906, retro_etel_507, retro_etel_839, retro_etel_841,
Felis catus	ENSFCAG00000028656	1 retrocopy	retro_fcat_1511,
Homo sapiens	ENSG00000241837	1 retrocopy	retro_hsap_2377,
Gorilla gorilla	ENSGGOG00000012611	1 retrocopy	retro_ggor_1803,
Macropus eugenii	ENSMEUG00000006613	4 retrocopies	retro_meug_122, retro_meug_1552, retro_meug_381, retro_meug_805,
Myotis lucifugus	ENSMLUG00000008224	3 retrocopies	retro_mluc_1833, retro_mluc_826, retro_mluc_856,
Macaca mulatta	ENSMMUG00000015504	1 retrocopy	retro_mmul_253 ,
Monodelphis domestica	ENSMODG00000021057	2 retrocopies	retro_mdom_280, retro_mdom_95,
Mustela putorius furo	ENSMPUG00000001319	5 retrocopies	retro_mputfur_1593, retro_mputfur_1628, retro_mputfur_1639, retro_mputfur_581, retro_mputfur_918,
Mus musculus	ENSMUSG00000022956	2 retrocopies	retro_mmus_2196, retro_mmus_955,
Otolemur garnettii	ENSOGAG00000015850	4 retrocopies	retro_ogar_3518, retro_ogar_418, retro_ogar_559, retro_ogar_944,
Pongo abelii	ENSPPYG00000011384	1 retrocopy	retro_pabe_2247,
Pan troglodytes	ENSPTRG00000013876	1 retrocopy	retro_ptro_1739,
Rattus norvegicus	ENSRNOG00000001991	1 retrocopy	retro_rnor_2210,
Sarcophilus harrisii	ENSSHAG00000000409	3 retrocopies	retro_shar_369, retro_shar_389, retro_shar_668,
Sus scrofa	ENSSSCG00000012042	2 retrocopies	retro_sscr_226, retro_sscr_566,
Ictidomys tridecemlineatus	ENSSTOG00000008658	3 retrocopies	retro_itri_1030, retro_itri_565, retro_itri_794,