RetrogeneDB ID: retro_mmus_686

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 10:130535586..130535961(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: Srp19
• Ensembl ID: ENSMUSG00000014504
• Aliases: Srp19, 2310020D23Rik
• Description: signal recognition particle 19 [Source:MGI Symbol;Acc:MGI:1913634]

Sequence

>retro_mmus_686
GCTTGTGCAGTCCCCGCCTACCAGGACAGGTTTATCTGAGTCTACCCTGCTTATTTAAATAGTAAGACCATAGCAGAGGG
GAGACGGATCCCCATAAGTAAGGCTGTAGAAAACCCTTCGACTACTGAGGTTCAAGATGTATGCTCAGCAGTTGGACTGA
ATGCCTTTCTGGAGAAAAACAAATTGTGCTCCAGAGAATGGAATCCTGATGTTCAGTACAGAGGCAGAGTCCGGGTACAG
CTCAAACAGGAAGATGCCAGCCTCTGTCTTGTATAGTTCCCATCATGTAAGTCAGTGATACTATACGTAGCAGAAATGAT
ACCAAAGCTAAAAACGAAGACACAGAAATCAGGAGGTGCTGACCCAAGTCTTAAG

Alignment

ORF - retro_mmus_686 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 83.33 %
• Parental protein coverage: 87.5 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  AARSPADQDRFICIYPAYLNNKKTIAEGRRIPISKAVENPTATEIQDVCSAVGLNAFLEKNKMYSREWNR
          A...PA.QDRFI..YPAYLN..KTIAEGRRIPISKAVENP..TE.QDVCSAVGLNAFLEKNK..SREWN.
Retrocopy ACAVPAYQDRFI*VYPAYLNS-KTIAEGRRIPISKAVENPSTTEVQDVCSAVGLNAFLEKNKLCSREWNP

Parental  DVQFRGRVRVQLKQEDGSLCLVQFPSRKSVMLYVAEMIPKLKTRTQKSGGADPSLQ
          DVQ.RGRVRVQLKQED.SLCLV.FPS.KSV.LYVAEMIPKLKT.TQKSGGADPSL.
Retrocopy DVQYRGRVRVQLKQEDASLCLV*FPSCKSVILYVAEMIPKLKTKTQKSGGADPSLK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.14 RPM	25.35 RPM
SRP007412_cerebellum	0.43 RPM	23.06 RPM
SRP007412_heart	0.00 RPM	23.66 RPM
SRP007412_kidney	0.02 RPM	23.93 RPM
SRP007412_liver	0.00 RPM	18.95 RPM
SRP007412_testis	0.00 RPM	33.44 RPM

ChIP-Seq

RNA Polymerase II actvity near the 5' end of retro_mmus_686 was not detected

EST

No EST(s) were mapped for retro_mmus_686 retrocopy.

TSS

No TSS is located nearby retro_mmus_686 retrocopy 5' end.

Lab

retro_mmus_686 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_686 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 23 parental genes, and 50 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000031549	5 retrocopies	retro_cfam_1207, retro_cfam_1717, retro_cfam_1791, retro_cfam_2174, retro_cfam_848,
Choloepus hoffmanni	ENSCHOG00000013452	2 retrocopies	retro_chof_2525, retro_chof_636,
Callithrix jacchus	ENSCJAG00000016512	4 retrocopies	retro_cjac_1117, retro_cjac_3059, retro_cjac_3144, retro_cjac_886,
Equus caballus	ENSECAG00000008895	1 retrocopy	retro_ecab_503,
Erinaceus europaeus	ENSEEUG00000007298	2 retrocopies	retro_eeur_593, retro_eeur_646,
Echinops telfairi	ENSETEG00000017132	4 retrocopies	retro_etel_1016, retro_etel_119, retro_etel_1268, retro_etel_1599,
Felis catus	ENSFCAG00000025895	1 retrocopy	retro_fcat_1732,
Homo sapiens	ENSG00000153037	1 retrocopy	retro_hsap_835,
Macropus eugenii	ENSMEUG00000012529	2 retrocopies	retro_meug_1220, retro_meug_1596,
Microcebus murinus	ENSMICG00000000399	1 retrocopy	retro_mmur_502,
Myotis lucifugus	ENSMLUG00000014793	3 retrocopies	retro_mluc_1097, retro_mluc_350, retro_mluc_710,
Macaca mulatta	ENSMMUG00000000331	2 retrocopies	retro_mmul_1088, retro_mmul_1970,
Monodelphis domestica	ENSMODG00000013278	3 retrocopies	retro_mdom_1366, retro_mdom_1880, retro_mdom_663,
Mustela putorius furo	ENSMPUG00000012695	2 retrocopies	retro_mputfur_602, retro_mputfur_706,
Mus musculus	ENSMUSG00000014504	3 retrocopies	retro_mmus_1680, retro_mmus_3241, retro_mmus_686 ,
Nomascus leucogenys	ENSNLEG00000011571	1 retrocopy	retro_nleu_3068,
Oryctolagus cuniculus	ENSOCUG00000015639	3 retrocopies	retro_ocun_1003, retro_ocun_1548, retro_ocun_729,
Otolemur garnettii	ENSOGAG00000008579	1 retrocopy	retro_ogar_2070,
Ochotona princeps	ENSOPRG00000010549	3 retrocopies	retro_opri_400, retro_opri_75, retro_opri_793,
Pongo abelii	ENSPPYG00000029584	1 retrocopy	retro_pabe_1569,
Pteropus vampyrus	ENSPVAG00000004895	1 retrocopy	retro_pvam_1465,
Rattus norvegicus	ENSRNOG00000020204	2 retrocopies	retro_rnor_1340, retro_rnor_997,
Ictidomys tridecemlineatus	ENSSTOG00000000348	2 retrocopies	retro_itri_318, retro_itri_831,