RetrogeneDB ID: retro_ocun_769

Retrocopy location

• Organism: Rabbit (Oryctolagus cuniculus)
• Coordinates: 14:110013243..110013763(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: TPRKB
• Ensembl ID: ENSOCUG00000016251
• Aliases: None
• Description: TP53RK binding protein [Source:HGNC Symbol;Acc:24259]

Sequence

>retro_ocun_769
ATGCAGTTAGTGCACCAGCTGGACTTGCTTCCCCAATGCAGGGTGACCCTTTTGTTGTTTAAAGACATAAAAAATGCAGG
AGACCTGAAGAAAAAGACCGTGGAAGGCACCACTGATGGTTCACTGAGAAATCCTGCAATGATTGGTGATCTGTTTCAGA
CACTTGTGGCAGCAAACAAGGCCATTCACTTCTACAGACTTGGAAAAATGAAGACAAGAATGCTGTTTACAGAAATTATT
TTCAGTCTTTCCCCAAACCACAATATTTCAGAAGCTTTGAAAAATTTTGTGTCTCAGGAAATGATACTTCAATTCTAATT
GTTTACGTTGAAGAGGGAGAAAAACAAACAGATCAACATCTAATAGTTCAAGTGGAAGGGCAGCAGGTTTCTCTGGAAAA
TCTCCCTGAAATAACAAATATTACAGAAGTCAAAAAGATACATAAACTGTCCTCACAAGAAGAAATATTGGGACATTATT
AGATGGTATCGCTTGTAGAATGCCAACAAAAGATGTTTTG

Alignment

ORF - retro_ocun_769 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 79.66 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MQLMHQLDLFPECRVTLLLFKDVKNAGDLRKKAMEGTIDGSLINPTVIVDPFQILVAANKAVHLYKLGKM
          MQL.HQLDL.P.CRVTLLLFKD.KNAGDL.KK..EGT.DGSL.NP..I.D.FQ.LVAANKA.H.Y.LGKM
Retrocopy MQLVHQLDLLPQCRVTLLLFKDIKNAGDLKKKTVEGTTDGSLRNPAMIGDLFQTLVAANKAIHFYRLGKM

Parental  KTRTLSTEIIFNLSPNNNISEALK-KFGISGNDTSILIVYVEEREKQINQEDLISQVEGQQVSLEKLPEI
          KTR.L.TEIIF.LSPN.NISEALK.KF..SGNDTSILIVYVEE.EKQ..Q..LI.QVEGQQVSLE.LPEI
Retrocopy KTRMLFTEIIFSLSPNHNISEALK<KFCVSGNDTSILIVYVEEGEKQTDQH-LIVQVEGQQVSLENLPEI

Parental  TNITEVKKIYKLSSQEE-SIGTLLDGIICRMSTKDVL
          TNITEVKKI.KLSSQEE..IGTLLDGI.CRM.TKDVL
Retrocopy TNITEVKKIHKLSSQEE<NIGTLLDGIACRMPTKDVL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	7.84 RPM
SRP017611_kidney	0.00 RPM	8.51 RPM
SRP017611_liver	0.00 RPM	4.47 RPM

ChIP-Seq

Oryctolagus cuniculus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ocun_769 retrocopy.

TSS

Oryctolagus cuniculus was not studied using FANTOM5 data.

Lab

retro_ocun_769 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ocun_769 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 14 parental genes, and 25 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000012021	1 retrocopy	retro_chof_35,
Callithrix jacchus	ENSCJAG00000004162	3 retrocopies	retro_cjac_1999, retro_cjac_2867, retro_cjac_3065,
Homo sapiens	ENSG00000144034	1 retrocopy	retro_hsap_552,
Gorilla gorilla	ENSGGOG00000009062	1 retrocopy	retro_ggor_501,
Macaca mulatta	ENSMMUG00000030805	1 retrocopy	retro_mmul_1571,
Monodelphis domestica	ENSMODG00000016950	2 retrocopies	retro_mdom_1264, retro_mdom_465,
Nomascus leucogenys	ENSNLEG00000000300	2 retrocopies	retro_nleu_2021, retro_nleu_957,
Oryctolagus cuniculus	ENSOCUG00000016251	2 retrocopies	retro_ocun_519, retro_ocun_769 ,
Otolemur garnettii	ENSOGAG00000032893	2 retrocopies	retro_ogar_523, retro_ogar_849,
Pongo abelii	ENSPPYG00000012292	1 retrocopy	retro_pabe_509,
Pteropus vampyrus	ENSPVAG00000012419	1 retrocopy	retro_pvam_75,
Ictidomys tridecemlineatus	ENSSTOG00000016406	4 retrocopies	retro_itri_1613, retro_itri_453, retro_itri_918, retro_itri_919,
Tupaia belangeri	ENSTBEG00000014584	2 retrocopies	retro_tbel_33, retro_tbel_3630,
Vicugna pacos	ENSVPAG00000007934	2 retrocopies	retro_vpac_149, retro_vpac_192,