RetrogeneDB ID: retro_ogar_765

Retrocopy location

• Organism: Bushbaby (Otolemur garnettii)
• Coordinates: GL873527.1:21360680..21361162(+)
• Located in intron of: ENSOGAG00000014187

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: HINT2
• Ensembl ID: ENSOGAG00000011830
• Aliases: None
• Description: histidine triad nucleotide binding protein 2 [Source:HGNC Symbol;Acc:18344]

Sequence

>retro_ogar_765
ATGGCGGCGGCCGTGGTGCTGACGGCGGCTTGTGCGTGGCGCCCAGAGCTATGGCAGTCGTGGGGCTGCGAGGGGCGCAG
GTCCCAAGAGCTCCAGGTGTGACTAATGGGAATGAAGTGGTCAAGGCCCAGCAGGCAGCTCCTGGTGGAGCAGCCGCAAC
CACCTTCTCCCGGATCCCGGACCGAAGCCTCCCAGCTGACATTCTATATGAGGACCAGCAGTGTCTCGTGTTCCATGATA
GCCCCTCAGGCTCCTGTGCACTCCTGGTCATTCCTAAGAAGCCTATTCCTCGGATTAGCCAGGCTGAAGAGGACCAGCAG
CTTCTAGGACACCTACTCCTTGTGGCCAAGACAATATCAAAGGCTGAAGGGTTAGGAGATGGATACCGACTTGTGATCAA
TGATGGGAAGCTGGGCGCACAATCTGTGTATCACCTGCATCTTCATGTATTTGGAGGCTGACAGCTCCAGTGGCCTCCAG
GT

Alignment

ORF - retro_ogar_765 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 85.54 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  MAAAVVLTA-GLRAARRAMAVAGPRGAQGRRVAGVTNGNEVVKAQQAAPGGAAPTIFSRILDRSLPADIL
          MAAAVVLTA.GL..A.RAMAV.G.RGAQ..R..GVTNGNEVVKAQQAAPGGAA.T.FSRI.DRSLPADIL
Retrocopy MAAAVVLTA<GLCVAPRAMAVVGLRGAQVPRAPGVTNGNEVVKAQQAAPGGAAATTFSRIPDRSLPADIL

Parental  YEDQQCLVFRDVAP-QAPVH-FLVIPKKPIPRISQAEEEDQQLLGHLLLVAKKIAKAEGLGDGYRLVIND
          YEDQQCLVF.D..P.QAPVH..LVIPKKPIPRISQA.EEDQQLLGHLLLVAK.I.KAEGLGDGYRLVIND
Retrocopy YEDQQCLVFHD-SP>QAPVH<LLVIPKKPIPRISQA-EEDQQLLGHLLLVAKTISKAEGLGDGYRLVIND

Parental  GKLGAQSVYHLHLHVLGGRQLQWPPG
          GKLGAQSVYHLHLHV.GG.QLQWPPG
Retrocopy GKLGAQSVYHLHLHVFGG*QLQWPPG

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Otolemur garnettii was not studied using RNA-Seq expression data.

ChIP-Seq

Otolemur garnettii was not studied using ChIP-Seq data.

EST

Otolemur garnettii was not studied using EST data.

TSS

Otolemur garnettii was not studied using FANTOM5 data.

Lab

retro_ogar_765 was not experimentally validated.

Homology

Retrocopy orthology:

Otolemur garnettii does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 27 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000011444	1 retrocopy	retro_btau_1129,
Callithrix jacchus	ENSCJAG00000010068	1 retrocopy	retro_cjac_1343,
Cavia porcellus	ENSCPOG00000000419	1 retrocopy	retro_cpor_181,
Dasypus novemcinctus	ENSDNOG00000009083	2 retrocopies	retro_dnov_201, retro_dnov_854,
Echinops telfairi	ENSETEG00000017929	1 retrocopy	retro_etel_486,
Homo sapiens	ENSG00000137133	1 retrocopy	retro_hsap_2603,
Gorilla gorilla	ENSGGOG00000011265	1 retrocopy	retro_ggor_1823,
Loxodonta africana	ENSLAFG00000015022	1 retrocopy	retro_lafr_737,
Macaca mulatta	ENSMMUG00000016337	1 retrocopy	retro_mmul_1509,
Nomascus leucogenys	ENSNLEG00000026914	1 retrocopy	retro_nleu_1534,
Oryctolagus cuniculus	ENSOCUG00000027206	1 retrocopy	retro_ocun_66,
Otolemur garnettii	ENSOGAG00000008850	2 retrocopies	retro_ogar_1028, retro_ogar_1599,
Otolemur garnettii	ENSOGAG00000011830	1 retrocopy	retro_ogar_765 ,
Pongo abelii	ENSPPYG00000019082	1 retrocopy	retro_pabe_2310,
Pan troglodytes	ENSPTRG00000020923	1 retrocopy	retro_ptro_1754,
Pteropus vampyrus	ENSPVAG00000003028	1 retrocopy	retro_pvam_842,
Tupaia belangeri	ENSTBEG00000013020	1 retrocopy	retro_tbel_4676,
Tarsius syrichta	ENSTSYG00000002700	7 retrocopies	retro_tsyr_1210, retro_tsyr_1356, retro_tsyr_1483, retro_tsyr_1485, retro_tsyr_311, retro_tsyr_468, retro_tsyr_48,
Tursiops truncatus	ENSTTRG00000011932	1 retrocopy	retro_ttru_1302,