RetrogeneDB ID: retro_cjac_3986

Retrocopy location

• Organism: Marmoset (Callithrix jacchus)
• Coordinates: GL286474.1:24210..25460(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ZC3H15
• Ensembl ID: ENSCJAG00000005931
• Aliases: None
• Description: None

Sequence

>retro_cjac_3986
ATGCCCCCCAGGAAACATGCTCAGGCTGGGGGCAAAAAGACAGAGCAGGAAAAGAGGGAGATTAACAAAGACAAAACTTT
TTGTTTGAAGAATAAGAAAGGACCAAAGAAACATAATTTTATCAAGGCTGTCACACACCAAGTTAAGTTTGGTCAACAAA
GTCCACGTCAGGTAGGACAGAGTAAAGCTGAAAAGAAATTGAAGAAGGATGACAAGAAGAATTGCAGGAGCTAAATGAGC
TGTTCAAACCTGTAGTTGCTCAAAAAATAAGTCAGGTGCAGAATCCAAGTCTGTGGTGTTTGCATTCTTCAAGCAAGGAC
AGTGTACCAAAGGAGATAAGTGTAAGTTCTCCCATGACTTGACTCTGGAGAGAAATGTGAAAAGCAAAGTGTTTACATGA
TGCAAGAAATGAAGAACTTGAAAAGGATACTACGGATAATTGGGATGAGAAGAAGCTGGAAGAAGTAGTGAACAAGAAGC
ACGGTGAGGCAGAAAAGAAAAAACCAAAAACTCAGTGTGCAAGCATTTTCTTGAAGCTATTGAAAACAACAAGTATGGCT
GGTTTGGGGTATGCCCTGGAGGGGGTGATATTTGCATGTATCAGCATACACTTACTCCTGGATTTGTGTTGAAAAAAATG
AAAGAACAGAAAGAGCGTGAAATTTCATTATAAGATCTAATTGAAAGAGAACGTTCTGCCCGCGGTCCAAATGTTACCAA
AATCACTCTAGAATCTTTTCTTGCATGGGAGAAAAGGAAAAGACAAGAAAAGACTGATAGACTTGAGCAAGATATTGAAA
GGAAGAAAGCTGACTTCAAAGCAGGAAAAGCACTCGTGATCTGTGGTCATGAGGTGTTTGAATTTTTCCTGAACTGGTCA
ATGATGATGATGACGAATCAGATGATACTTGCTACACCCAGGGAACAGGTGGTGATAAGGTTGATAATTCAGTGAGTGTA
AATGACATAGATGTAAGCCTGTACATCCCAAGAGATGCAGGTGAAACGGGTATTACTGTAGCCAGTCTGGAAGATGCAGC
ACATATACTTCAGATAAAGATGAAAACAAATTAAGTGAAGCTTCTGGAGGTAGGGCTGAAAATGGTGAAAGAATTTACTT
GGAAGAGGACAACGAAGGGGCAGGACTGAAGAATGGAGCTGTTGATGGTGTTCTTGTTGATAAAAATCTTTTCACTGGAG
AAAATTTGGATGAACTACAAGAGGAATTAAATACACTTGATTTAGGAGAA

Alignment

ORF - retro_cjac_3986 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 81.06 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 7

Retrocopy - Parental Gene Alignment:

Parental  MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLK
          MPP.K.AQAGG.KK.EQ.K.E.I..DKTF.LKNKKG.K...FIKAVTHQVKFGQQ.PRQV.QS.AEKKLK
Retrocopy MPPRKHAQAGG-KKTEQEKRE-INKDKTFCLKNKKGPKKHNFIKAVTHQVKFGQQSPRQVGQSKAEKKLK

Parental  KDDKKK-ELQELNELFKPVVAAQKISK-GADPKSVVCAFFKQGQCTKGDKCKFSHDLTLER-KCEKRSVY
          KDD.KK.ELQELNELFKPVVA.QKIS..GA..KSVV.AFFKQGQCTKGDKCKFSHDLTLER.KCEK.SVY
Retrocopy KDD-KK<ELQELNELFKPVVA-QKISQ<GAESKSVVFAFFKQGQCTKGDKCKFSHDLTLER<KCEKQSVY

Parental  I-DARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKK-KPKTQIVCKHFLEAIENNKYGWFWVCPGGGDIC
          ..DAR.EELEKDT.DNWDEKKLEEVVNKKHGEAEKK.K.K...VCKHFLEAIENNKYGWF.VCPGGGDIC
Retrocopy M<DARNEELEKDTTDNWDEKKLEEVVNKKHGEAEKK<KTKNS-VCKHFLEAIENNKYGWFGVCPGGGDIC

Parental  MYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDME
          MY.H.L.PGFVLKK...KE.KE.EISL.DLIERERSA.GPNVTKITLESFLAW.KRKRQEK.D.LEQD.E
Retrocopy MYQHTLTPGFVLKK--MKEQKEREISL*DLIERERSARGPNVTKITLESFLAWEKRKRQEKTDRLEQDIE

Parental  RRKADFKAGKALVISGREVFEF-RPELVNDDDEEADDTHYTQGTGGDEVDDSVSINDIDLSQYIPRDVDE
          R.KADFKAGKALVI.G.EVFEF..PELVNDDD.E.DDT.YTQGTGGD.VD.SVS.NDID.S.YIPRD..E
Retrocopy RKKADFKAGKALVICGHEVFEF<FPELVNDDDDESDDTCYTQGTGGDKVDNSVSVNDIDVSLYIPRDAGE

Parental  TGITVASLE-RFSTYTSDKDENKLNEASGGRAENGERSDLEEDNEREGPENGAIDAVPVDENLFTGEDLD
          TGITVASLE.R.STYTSDKDENKL.EASGGRAENGER..LEEDNE..G..NGA.D.V.VD.NLFTGE.LD
Retrocopy TGITVASLE<RCSTYTSDKDENKLSEASGGRAENGERIYLEEDNEGAGLKNGAVDGVLVDKNLFTGENLD

Parental  ELEEELNTLDLEE
          EL.EELNTLDL.E
Retrocopy ELQEELNTLDLGE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP051959_colon	0.00 RPM	20.86 RPM
SRP051959_heart	0.00 RPM	15.49 RPM
SRP051959_kidney	0.00 RPM	31.64 RPM
SRP051959_liver	0.00 RPM	25.08 RPM
SRP051959_lung	0.00 RPM	23.83 RPM
SRP051959_lymph_node	0.00 RPM	26.73 RPM
SRP051959_skeletal_muscle	0.00 RPM	15.05 RPM
SRP051959_spleen	0.00 RPM	26.66 RPM

ChIP-Seq

Callithrix jacchus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cjac_3986 retrocopy.

TSS

Callithrix jacchus was not studied using FANTOM5 data.

Lab

retro_cjac_3986 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cjac_3986 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 13 parental genes, and 24 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000021762	1 retrocopy	retro_btau_1223,
Choloepus hoffmanni	ENSCHOG00000011958	1 retrocopy	retro_chof_2120,
Callithrix jacchus	ENSCJAG00000005931	2 retrocopies	retro_cjac_2883, retro_cjac_3986 ,
Cavia porcellus	ENSCPOG00000012965	2 retrocopies	retro_cpor_1294, retro_cpor_919,
Dipodomys ordii	ENSDORG00000011664	1 retrocopy	retro_dord_666,
Loxodonta africana	ENSLAFG00000001563	1 retrocopy	retro_lafr_941,
Monodelphis domestica	ENSMODG00000027565	5 retrocopies	retro_mdom_1230, retro_mdom_1321, retro_mdom_1744, retro_mdom_1942, retro_mdom_871,
Oryctolagus cuniculus	ENSOCUG00000011903	1 retrocopy	retro_ocun_886,
Otolemur garnettii	ENSOGAG00000002182	2 retrocopies	retro_ogar_1093, retro_ogar_611,
Ochotona princeps	ENSOPRG00000015790	2 retrocopies	retro_opri_169, retro_opri_609,
Pan troglodytes	ENSPTRG00000012717	1 retrocopy	retro_ptro_348,
Rattus norvegicus	ENSRNOG00000005256	4 retrocopies	retro_rnor_2628, retro_rnor_284, retro_rnor_662, retro_rnor_925,
Sorex araneus	ENSSARG00000012071	1 retrocopy	retro_sara_363,