RetrogeneDB ID: retro_ggor_1365

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 18:3428021..3428461(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000025977
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: BOD1
• Ensembl ID: ENSGGOG00000010925
• Aliases: None
• Description: None

Sequence

>retro_ggor_1365
GGCAACGCAGGCACCATGATCCCGGCTCTGCCTTCCGGCGACCCGGAGCTCATTGCTCTCATCCTGGAGTGGCTCAAGAG
CCAGGCCCGTTTGGCAGCTTCTGTCGATGCTGCCTGGCCCCTGTGGACACCAAGCCAGCTTACCAAAACCGGAGGCAGAA
AGCTGAGCGTTCGGCGTCCACACACCTGGATGAGCAGAACTGGAGTCTTATGATGCGCAAAAGCCTATTGCGAAATGGTC
AGAGGCAGAGTGAGGTTCAGTCAGGGACATTGGAAGCTGGAGTAGACAGGGTTATTTCTCAGGCAGAGGATCCAAAATTA
AACCACATCCTCAGGCCACCAATGGAAGGAGCAAGTCATGAGTTCCTGGGTGCCCAGAAGACAGCAATGGTGCCAGCGCC
CCCTTTAGAGCCCGCAGACCAGGACCCTCCAGCTCCAGCC

Alignment

ORF - retro_ggor_1365 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 67.11 %
• Parental protein coverage: 80.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  GGGGPINPASLPPGDPQLIALIVEQLKSR-GLFDSFRRDCLADVDTKPAYQNLRQKVDNFVSTHLDKQEW
          G..G...PA.LP.GDP.LIALI.E.LKS..G.F.SF.R.CLA.VDTKPAYQN.RQK.....STHLD.Q.W
Retrocopy GNAGTMIPA-LPSGDPELIALILEWLKSQ<GPFGSFCRCCLAPVDTKPAYQNRRQKAERSASTHLDEQNW

Parental  NPTMNKNQLRNGLRQSVVQSGMLEAGVDRIISQVVDPKLNHIFRPQIERAIHEFLAAQKKAAVPAPPPEP
          ...M.K..LRNG.RQS.VQSG.LEAGVDR.ISQ..DPKLNHI.RP..E.A.HEFL.AQK.A.VPAPP.EP
Retrocopy SLMMRKSLLRNGQRQSEVQSGTLEAGVDRVISQAEDPKLNHILRPPMEGASHEFLGAQKTAMVPAPPLEP

Parental  EGQDPPAPS
          ..QDPPAP.
Retrocopy ADQDPPAPA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	28.92 RPM
SRP007412_cerebellum	0.00 RPM	21.08 RPM
SRP007412_heart	0.00 RPM	11.91 RPM
SRP007412_kidney	0.00 RPM	34.76 RPM
SRP007412_liver	0.00 RPM	21.13 RPM
SRP007412_testis	0.00 RPM	50.87 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1365 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1365 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1867
Pan troglodytes	retro_ptro_1282

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 30 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000034598	1 retrocopy	retro_btau_663,
Canis familiaris	ENSCAFG00000016776	1 retrocopy	retro_cfam_1374,
Callithrix jacchus	ENSCJAG00000031971	4 retrocopies	retro_cjac_1154, retro_cjac_1515, retro_cjac_1536, retro_cjac_953,
Homo sapiens	ENSG00000145919	3 retrocopies	retro_hsap_102, retro_hsap_1867, retro_hsap_993,
Gorilla gorilla	ENSGGOG00000010925	2 retrocopies	retro_ggor_1365 , retro_ggor_794,
Microcebus murinus	ENSMICG00000002626	1 retrocopy	retro_mmur_1126,
Macaca mulatta	ENSMMUG00000013793	2 retrocopies	retro_mmul_803, retro_mmul_869,
Mus musculus	ENSMUSG00000044502	1 retrocopy	retro_mmus_3661,
Nomascus leucogenys	ENSNLEG00000000476	1 retrocopy	retro_nleu_1224,
Oryctolagus cuniculus	ENSOCUG00000014283	1 retrocopy	retro_ocun_1071,
Otolemur garnettii	ENSOGAG00000001107	3 retrocopies	retro_ogar_1477, retro_ogar_2663, retro_ogar_3112,
Pongo abelii	ENSPPYG00000016057	2 retrocopies	retro_pabe_1567, retro_pabe_1587,
Pan troglodytes	ENSPTRG00000017544	2 retrocopies	retro_ptro_1282, retro_ptro_757,
Ictidomys tridecemlineatus	ENSSTOG00000013505	1 retrocopy	retro_itri_1164,
Tupaia belangeri	ENSTBEG00000014046	1 retrocopy	retro_tbel_3451,
Tarsius syrichta	ENSTSYG00000007617	1 retrocopy	retro_tsyr_818,
Tursiops truncatus	ENSTTRG00000000384	2 retrocopies	retro_ttru_1004, retro_ttru_457,
Vicugna pacos	ENSVPAG00000004260	1 retrocopy	retro_vpac_452,