RetrogeneDB ID: retro_ptro_294

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 1:46207241..46207607(-)
• Located in intron of: ENSPTRG00000000683

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: TMA16
• Ensembl ID: ENSPTRG00000023618
• Aliases: None
• Description: translation machinery associated 16 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25638]

Sequence

>retro_ptro_294
TTAAATTGATTTAGCAGTGAGTTGGAGCAGATTGAGTTACATAACAGTATCAGGGACAAGCAGGACAGGCAGCACTGTTT
CCAGGACGCCATCATCAAGCAGACGATGGAGCGGGAGGGACAGCAGTATAAAGGATGTGGCCTTGAGATTCCAGACATTC
TAAATGCAAGTAATCTGAAAACATTTAGGGAATGGGACTTTGATCTGAAGAAATTGCCAAATATTAAAATGAGAAAAATC
TGCGCTGATGATGCAATTCCCAAGAAGTGCAAGAGGAAAACTATTATAACTACAGACCAAGATTTAGTGGAATTGGAACT
AAACGATGAATCAAATGACTCAGATGAGGAAATGACTGGATTAGCC

Alignment

ORF - retro_ptro_294 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 82.79 %
• Parental protein coverage: 60.1 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  LNRFSSELEQIELHNSIRDRQGRRHCSRETVIKQTMERERQQFEGYGLEIPDILNASNLKTFREWDFDLK
          LN.FSSELEQIELHNSIRD.Q.R.HC.....IKQTMERE.QQ..G.GLEIPDILNASNLKTFREWDFDLK
Retrocopy LN*FSSELEQIELHNSIRDKQDRQHCFQDAIIKQTMEREGQQYKGCGLEIPDILNASNLKTFREWDFDLK

Parental  KLPNIKMRKICANDAIPKTCKRKTIIPVDQDLGELELNDESSDSDEEMTAVA
          KLPNIKMRKICA.DAIPK.CKRKTII..DQDL.ELELNDES.DSDEEMT..A
Retrocopy KLPNIKMRKICADDAIPKKCKRKTIITTDQDLVELELNDESNDSDEEMTGLA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	3.25 RPM
SRP007412_cerebellum	0.00 RPM	3.66 RPM
SRP007412_heart	0.00 RPM	4.61 RPM
SRP007412_kidney	0.00 RPM	4.24 RPM
SRP007412_liver	0.00 RPM	9.75 RPM
SRP007412_testis	0.11 RPM	37.62 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_294 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_294 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_294 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_378
Pongo abelii	retro_pabe_329

---

Parental genes homology:

Parental genes homology involve 19 parental genes, and 37 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000006702	2 retrocopies	retro_chof_1717, retro_chof_2104,
Cavia porcellus	ENSCPOG00000001119	1 retrocopy	retro_cpor_444,
Dasypus novemcinctus	ENSDNOG00000006820	1 retrocopy	retro_dnov_489,
Echinops telfairi	ENSETEG00000009734	1 retrocopy	retro_etel_1378,
Homo sapiens	ENSG00000198498	2 retrocopies	retro_hsap_378, retro_hsap_879,
Gorilla gorilla	ENSGGOG00000025324	1 retrocopy	retro_ggor_713,
Macropus eugenii	ENSMEUG00000001134	3 retrocopies	retro_meug_1830, retro_meug_1895, retro_meug_396,
Macaca mulatta	ENSMMUG00000004482	2 retrocopies	retro_mmul_184, retro_mmul_276,
Monodelphis domestica	ENSMODG00000002170	1 retrocopy	retro_mdom_881,
Mus musculus	ENSMUSG00000025591	2 retrocopies	retro_mmus_299, retro_mmus_329,
Nomascus leucogenys	ENSNLEG00000006466	2 retrocopies	retro_nleu_1631, retro_nleu_2590,
Otolemur garnettii	ENSOGAG00000001860	1 retrocopy	retro_ogar_3308,
Pongo abelii	ENSPPYG00000015167	1 retrocopy	retro_pabe_329,
Pan troglodytes	ENSPTRG00000023618	2 retrocopies	retro_ptro_294 , retro_ptro_3035,
Rattus norvegicus	ENSRNOG00000014188	3 retrocopies	retro_rnor_2309, retro_rnor_845, retro_rnor_846,
Sorex araneus	ENSSARG00000003780	1 retrocopy	retro_sara_168,
Ictidomys tridecemlineatus	ENSSTOG00000024763	3 retrocopies	retro_itri_1085, retro_itri_1372, retro_itri_715,
Tupaia belangeri	ENSTBEG00000017224	7 retrocopies	retro_tbel_168, retro_tbel_2196, retro_tbel_2345, retro_tbel_2474, retro_tbel_3235, retro_tbel_3987, retro_tbel_4393,
Tarsius syrichta	ENSTSYG00000008284	1 retrocopy	retro_tsyr_686,