RetrogeneDB ID:

retro_ptro_3229

Retrocopy
location
Organism:Chimpanzee (Pan troglodytes)
Coordinates:X:67812663..67813491(-)
Located in intron of:ENSPTRG00000021979
Retrocopy
information
Ensembl ID:None
Aliases:None
Status:NOVEL
Parental gene
information
Parental gene summary:
Parental gene symbol:PGK1
Ensembl ID:ENSPTRG00000022052
Aliases:None
Description:Pan troglodytes phosphoglycerate kinase 1 (PGK1), mRNA. [Source:RefSeq mRNA;Acc:NM_001135738]


Retrocopy-Parental alignment summary:






>retro_ptro_3229
AGTGAGCCCGCCAAAATAGAAGCTTTCCGAGCTTCACTTTCCACGCTAGGGAATGTGTATGTCAATGGTGCTTTTGGCAC
TGCTCACAGAGCCCACAGCTCCATGGTAGGAGTCAGTCTGCCACAGAAGGCTGGTGGTTTTTTGATGAAGAAGGAGCTGA
ACTACTTTGTGAAGGTCTTGGAGAGCCCATAGCGACCCTTCCTGGCCATTCTGGGTGGAGCTAAATTTGCAGACAAGATC
CACCTGATCAATAATATGCTGGACAAAGTCAATGAGATGATTATTGGTGGTGGAACGGCTTTTACCTTCCTTAAGGTGCT
CAACAACATGGAGACTGGCACTTCTCTGTTTGATGAAGAGGGAGCCAAGATTGTCAAAGACCTAATGTCCCAAGCTGAGA
AGAATGGTGTGAAGATTACCTTGCCTATTGACTTTGTCACTGCTGAGAAATTTGATGAGAATGCCAAGACTGGCCAAGCC
ACTGTGGCTTCTGGCATACCTGCTGGCTGAATGGGCTTGGACTGTGGTCCTGAAAGCAGCAAGAAGTATGCTGAGACTGT
CACTTGGGCTAAGCAGATTGTGTGGAATGGTCCTGTGGGGGTATTTGAATGGGAAGCTTTTGCCCAGGGAACCAAAGCCC
TCATGGACGAGGTGGTGAAAGCCACTTCTAGGGGCTGCACTACCATCATAGGTGGTGGAAACACTGCCACTTGTTGTGCC
AAATGGAACACAGAGGATAAAATCAGACATGTGAGCACTAGGGGTGGTGCCAGTTTAGAGCTCCTGGACGGTAAAGTCCT
TCCTGGGGTGGATGCTCTCGGCAATATT

ORF - retro_ptro_3229 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 90.58 %
Parental protein coverage: 99.28 %
Number of stop codons detected: 2
Number of frameshifts detected 0


Retrocopy - Parental Gene Alignment:

ParentalAEPAKIEAFRASLS-LGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAI
.EPAKIEAFRASLS.LG.VYVN.AFGTAHRAHSSMVGV.LPQKAGGFLMKKELNYF.K.LESP.RPFLAI
RetrocopySEPAKIEAFRASLSTLGNVYVNGAFGTAHRAHSSMVGVSLPQKAGGFLMKKELNYFVKVLESP*RPFLAI
ParentalLGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKIT
LGGAK.ADKI.LINNMLDKVNEMIIGGG.AFTFLKVLNNME.GTSLFDEEGAKIVKDLMS.AEKNGVKIT
RetrocopyLGGAKFADKIHLINNMLDKVNEMIIGGGTAFTFLKVLNNMETGTSLFDEEGAKIVKDLMSQAEKNGVKIT
ParentalLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARG
LP.DFVTA.KFDENAKTGQATVASGIPAG.MGLDCGPESSKKYAE.VT.AKQIVWNGPVGVFEWEAFA.G
RetrocopyLPIDFVTAEKFDENAKTGQATVASGIPAG*MGLDCGPESSKKYAETVTWAKQIVWNGPVGVFEWEAFAQG
ParentalTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI
TKALMDEVVKATSRGC.TIIGGG.TATCCAKWNTEDK..HVST.GGASLELL.GKVLPGVDAL.NI
RetrocopyTKALMDEVVKATSRGCTTIIGGGNTATCCAKWNTEDKIRHVSTRGGASLELLDGKVLPGVDALGNI

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
SRP007412_brain_prefrontal_cortex 2 .32 RPM 170 .83 RPM
SRP007412_cerebellum 0 .07 RPM 138 .09 RPM
SRP007412_heart 0 .09 RPM 182 .98 RPM
SRP007412_kidney 0 .16 RPM 194 .91 RPM
SRP007412_liver 0 .10 RPM 151 .59 RPM
SRP007412_testis 0 .00 RPM 31 .40 RPM
Pan troglodytes was not studied using ChIP-Seq data.
No EST(s) were mapped for retro_ptro_3229 retrocopy.
Pan troglodytes was not studied using FANTOM5 data.
retro_ptro_3229 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_ptro_3229 has 3 orthologous retrocopies within eutheria group .

Species RetrogeneDB ID
Homo sapiens retro_hsap_4850
Gorilla gorilla retro_ggor_3026
Pongo abelii retro_pabe_3770

Parental genes homology:
Parental genes homology involve 29 parental genes, and 52 retrocopies.

Species Parental gene accession Retrocopies number
Ailuropoda melanoleuca ENSAMEG000000176191 retrocopy
Bos taurus ENSBTAG000000008941 retrocopy
Canis familiaris ENSCAFG000000172702 retrocopies
Callithrix jacchus ENSCJAG000000210823 retrocopies
Cavia porcellus ENSCPOG000000237851 retrocopy
Equus caballus ENSECAG000000149841 retrocopy
Felis catus ENSFCAG000000132092 retrocopies
Homo sapiens ENSG000001021442 retrocopies
Gorilla gorilla ENSGGOG000000171113 retrocopies
Loxodonta africana ENSLAFG000000119541 retrocopy
Macropus eugenii ENSMEUG000000047793 retrocopies
Myotis lucifugus ENSMLUG000000177912 retrocopies
Macaca mulatta ENSMMUG000000128741 retrocopy
Monodelphis domestica ENSMODG000000040552 retrocopies
Mus musculus ENSMUSG000000620702 retrocopies
Nomascus leucogenys ENSNLEG000000014233 retrocopies
Oryctolagus cuniculus ENSOCUG000000147261 retrocopy
Otolemur garnettii ENSOGAG000000111041 retrocopy
Procavia capensis ENSPCAG000000021171 retrocopy
Pongo abelii ENSPPYG000000204963 retrocopies
Pan troglodytes ENSPTRG00000022052 2 retrocopies
retro_ptro_2, retro_ptro_3229 ,
Rattus norvegicus ENSRNOG000000024677 retrocopies
Sorex araneus ENSSARG000000039561 retrocopy
Sarcophilus harrisii ENSSHAG000000018531 retrocopy
Sus scrofa ENSSSCG000000124401 retrocopy
Ictidomys tridecemlineatus ENSSTOG000000019721 retrocopy
Tupaia belangeri ENSTBEG000000103091 retrocopy
Tarsius syrichta ENSTSYG000000079171 retrocopy
Vicugna pacos ENSVPAG000000012081 retrocopy



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