RetrogeneDB ID: retro_tbel_3697

Retrocopy location

• Organism: Treeshrew (Tupaia belangeri)
• Coordinates: scaffold_148748:17087..17998(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PAICS
• Ensembl ID: ENSTBEG00000006751
• Aliases: None
• Description: phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase [Source:HGNC Symbol;Acc:8587]

Sequence

>retro_tbel_3697
AAAAACTATGGAGGTAAAACAAAAGAAGTCTATGAACTGTTAAATAGTCCAGGAAAAGTCCTCCAGCAGTCCAAGGGCCA
GATTACTGCAGGAAATGCAGCTAGAAAGAATCATCTGGAAGGAAAAGATGCAATCTCAAATAAAATTACCAGTTGTATTT
CTCAGTTGTTATTGGAAGCAGATACCAAAATTGCTTTCACCAGAAAATGTGCAGAGACAACTTCCATTGCACCCCAGTGT
GAAATGATTCCAGTTGAATGGGTTTGCAAGCAGAATACCAACAGGTTCTTTTCTCAAAAGAAATCCTGGCATCAAGGAAG
GATATAAGTTTTACCCACCTAAAGTGAAGCTGTTCTTTAAGGATGATGCCAACAATGACCAACAGTGGTCTGAGGAACAG
TTGATGGCTGCAAAATTTTGCTTTACTGGACTTGTGATAGGCCAAACTGAAGTGGATACCATGAGTCATGCTACCCAGGC
TATCTTTGAAATATTGGAGAAATCCTGGTTGCCCCAGAACTGTACACTGGTTGACATGAAGATTGAATTTGGTGTTGATG
TAACCACCAAAGAAATTGTTCTTGCTGATGTTGTTGATAATGATTCCTGGAGACTCCAGCCATCTGGAGATCAAAGTCAA
TAGAAAGAAAAAAGTCTTACCATAACCTCAAAGAAGTAACTCCCAAAGGGGTCCATATGTTAAAGAGAAACTGAGTGGAT
TGCAGAGAATAAAGTTGCTTCTTAAATCAGAAAGTCAATGCAGGGTTGTACTATTGACGGGCTCAACTTCTGATCTTGAT
CACTGTGAATAAAATCAAGAAAGCCTGTGGAAATTTTGGCATTCCCTGTGAATTCAGGTAATACCTGCCCACAGAGAGCC
AGATAAAACTCTGAGGATTAAAGCTGAATAT

Alignment

ORF - retro_tbel_3697 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 79.35 %
• Parental protein coverage: 67.63 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 5

Retrocopy - Parental Gene Alignment:

Parental  KLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKTTSCIFQLLQEAGIKTAFTRKC
          K.Y.GKTKEVYELL.SPGKVL.QSK.QITAGNAARKNHLEGK.AISNK.TSCI.QLL.EA..K.AFTRKC
Retrocopy KNYGGKTKEVYELLNSPGKVLQQSKGQITAGNAARKNHLEGKDAISNKITSCISQLLLEADTKIAFTRKC

Parental  GETAFIAPQCEMIPIEWVCR-RIATGSFLKRNPGVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKF
          .ET..IAPQCEMIP.EWVC..RI.TGSFLKRNPG.KEGYKFYPPKV.LFFKDDANND.QWSEEQL.AAKF
Retrocopy AETTSIAPQCEMIPVEWVCK>RIPTGSFLKRNPGIKEGYKFYPPKVKLFFKDDANNDQQWSEEQLMAAKF

Parental  CFAGLEIGQTEVDIMSHATQAIFEILERSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSG
          CF.GL.IGQTEVD.MSHATQAIFEILE.SWLPQNCTLVDMKIEFGVDVTTKEIVLADV.DNDSWRL.PSG
Retrocopy CFTGLVIGQTEVDTMSHATQAIFEILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVVDNDSWRLQPSG

Parental  DRSQQKDK-QCYRDLKEVTPENLQM-VKRNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCE-KIRKA
          D.SQ.K.K...Y..LKEVTP....M.VK........R..LLLKSESQCRVV.L.GSTSDL.HCE.KI.KA
Retrocopy DQSQ*KEK<KSYHNLKEVTPKGVHM<VKEKLSGL-QRIKLLLKSESQCRVVLLTGSTSDLDHCE>KIKKA

Parental  CGNFGIPCELR-VTSAHKGPDETLRIKAEY
          CGNFGIPCE.R.V..AH..PD.TLRIKAEY
Retrocopy CGNFGIPCEFR<VIPAHREPDKTLRIKAEY

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Tupaia belangeri was not studied using RNA-Seq expression data.

ChIP-Seq

Tupaia belangeri was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_tbel_3697 retrocopy.

TSS

Tupaia belangeri was not studied using FANTOM5 data.

Lab

retro_tbel_3697 was not experimentally validated.

Homology

Retrocopy orthology:

Tupaia belangeri does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 29 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000010577	1 retrocopy	retro_btau_508,
Cavia porcellus	ENSCPOG00000010749	1 retrocopy	retro_cpor_969,
Dasypus novemcinctus	ENSDNOG00000013413	1 retrocopy	retro_dnov_284,
Echinops telfairi	ENSETEG00000015242	2 retrocopies	retro_etel_1918, retro_etel_341,
Homo sapiens	ENSG00000128050	3 retrocopies	retro_hsap_3802, retro_hsap_3915, retro_hsap_3927,
Gorilla gorilla	ENSGGOG00000024392	1 retrocopy	retro_ggor_2643,
Mus musculus	ENSMUSG00000029247	6 retrocopies	retro_mmus_1748, retro_mmus_2750, retro_mmus_2858, retro_mmus_3126, retro_mmus_653, retro_mmus_971,
Nomascus leucogenys	ENSNLEG00000008786	2 retrocopies	retro_nleu_1274, retro_nleu_2156,
Otolemur garnettii	ENSOGAG00000003575	2 retrocopies	retro_ogar_2138, retro_ogar_865,
Procavia capensis	ENSPCAG00000008531	1 retrocopy	retro_pcap_172,
Pan troglodytes	ENSPTRG00000016081	2 retrocopies	retro_ptro_2662, retro_ptro_2670,
Rattus norvegicus	ENSRNOG00000002101	3 retrocopies	retro_rnor_1891, retro_rnor_2768, retro_rnor_804,
Tupaia belangeri	ENSTBEG00000006751	1 retrocopy	retro_tbel_3697 ,
Tarsius syrichta	ENSTSYG00000010497	2 retrocopies	retro_tsyr_2170, retro_tsyr_329,
Drosophila melanogaster	FBgn0020513	1 retrocopy	retro_dmel_82,