miRNEST 2.0: an integrative microRNA resource miRNEST 2.0, an integrative microRNA resource :: Browse

Species belonging to selected taxon:

Caenorhabditis elegans, Ancylostoma caninum, Ascaris suum, Heterorhabditis bacteriophora, Brachionus plicatilis, Pristionchus pacificus, Caenorhabditis japonica, Caenorhabditis brenneri, Strongyloides ratti, Brugia malayi, Trichinella spiralis, Meloidogyne hapla, Heterodera glycines, Meloidogyne incognita, Caenorhabditis remanei, Trichinella pseudospiralis, Onchocerca volvulus, Nippostrongylus brasiliensis, Meloidogyne chitwoodi, Globodera rostochiensis, Strongyloides stercoralis, Ancylostoma ceylanicum



ABOUT THIS RECORD

ID: MNEST038263
species: Caenorhabditis elegans
miRNA family: let-7
source: miRBase, original name: cel-let-7 (MI0000001)

Taxonomy by NCBI:
Caenorhabditis elegans Caenorhabditis Peloderinae Rhabditidae Rhabditoidea Rhabditida Chromadorea Nematoda Pseudocoelomata Bilateria Eumetazoa Metazoa Fungi/Metazoa group Eukaryota cellular organisms






SEQUENCE & STRUCTURE
miRNA
TGAGGTAGTAGGTTGTATAGTT

miRNA*
CTATGCAATTTTCTACCTTACC

mismatches: 1
bulges: 0

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pre-miRNA
TACACTGTGGATCCGGTGAGGTAGTAGGTTGTATAGTTTGGAATATTACCACCGGTGAACTATGCAATTTTCTACCTTACCGGAGACAGAACTCTTCGA

dot-bracket secondary structure
....((((...(((((((((((((.((((((((((((((((..........))...)))))))))))))).))))))))))))).))))..........


SIMILARITIES
miRBase cbr-let-7: 4e-19

PMRD no hits

microPC no hits
UniProt no hits

RFAM let-7: 1e-34

MORE

miRNEST target predictions: none
non-miRNEST targets
HuntMi prediction: true miRNA
additional data
download this record
evidence: cloned, Northern, PCR, Solexa
deep sequencing data evidence

references

[1] Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D, Curr Biol. 13:807-818(2003)., "MicroRNAs and other tiny endogenous RNAs in C. elegans"
[2] Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP, Genes Dev. 17:991-1008(2003)., "The microRNAs of Caenorhabditis elegans"
[3] Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP, Cell. 127:1193-1207(2006)., "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans"
[4] Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J, Mol Cell. 11:1253-1263(2003)., "Computational and experimental identification of C. elegans microRNAs"
[5] Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW, Nat Struct Mol Biol. 17:173-179(2010)., "Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans"
[6] Kato M, de Lencastre A, Pincus Z, Slack FJ, Genome Biol. 10:R54(2009)., "Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development"
[7] Lau NC, Lim LP, Weinstein EG, Bartel DP, Science. 294:858-862(2001)., "An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans"




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