RetrogeneDB ID: retro_chof_1648

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_350576:383..913(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: CCDC59
• Ensembl ID: ENSCHOG00000007788
• Aliases: None
• Description: coiled-coil domain containing 59 [Source:HGNC Symbol;Acc:25005]

Sequence

>retro_chof_1648
TTCAAAGAAAACAGAAAACTGAAGATTCAGCAAAATTACAATAAATTGCCACGGAAGACAAAAAAATTCTCAAACCTTAC
GAGAATCCCAAGTCTCAGATTGATACCCAGATCATCTGAAACACCTCTATTTAGCTGAAGAGGAAAGGCTTAGAAAGCAA
CTTTAAAAAGTTGACCAAACTTTGTCAGAAGAACAAGTTGACCAACATTTGCCAGAACAAGGTAGTGTTGATCAGGCTTC
GTGAAGAAAATGTCGCATTGACCAGCCTCTACCAGCAAGACAAAGCAGTGAAACAGTAAACTTCATTGCTACTTCAAAGA
AATATAAAAAGAAAACATCAAATTAAAAAGCACAAGAATAATGATAACAGGTATGAGCTAAGTGTGCTGCTAAGAAACAA
TCTGAGACAAGAGCATGAGAGAGAAGAATCTCAGAGGCTCTACAAAAAGAAAAAAATGAAAGTGTTCAAACTATTGAGCA
AAAGGATTAAAAAGGGCTAACCAAATTTGAATTTACAAATGGAGTATCTT

Alignment

ORF - retro_chof_1648 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 66.3 %
• Parental protein coverage: 73.97 %
• Number of stop codons detected: 9
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  FAFRRKLKIQQNYKKLLWKTKK-AQTSQESQFTDRYPDHLKHLYLAEEERLRKQLKKVDQTFSEGQIDQP
          F...RKLKIQQNY.KL..KTKK..QT..ESQ..D.YPDHLKHLYLAEEERLRKQL.KVDQT.SE.Q.DQ.
Retrocopy FKENRKLKIQQNYNKLPRKTKK>SQTLRESQVSD*YPDHLKHLYLAEEERLRKQL*KVDQTLSEEQVDQH

Parental  LREQCSVDQALSEEHCSIEQPLPAGQSSETVNSIATSKKYKKKTSNQKAQEEYEQVQAKRAAKKQEFER-
          L.EQ.SVDQA.S...C.I.QPLPA.QSSETVN.IATSKKYKKKTSN.KAQE...QV.AK.AAKKQ...R.
Retrocopy LPEQGSVDQA-S*RKCRIDQPLPARQSSETVNFIATSKKYKKKTSN*KAQE***QV*AKCAAKKQSETR>

Parental  RKREREEAQRLYKKKKMEVFKILSKRTKKGQPNLNLQMEYL
          ..RE..E.QRLY.................G.PNLNLQMEYL
Retrocopy HERE--ESQRLYXXXXXXXXXXXXXXXXXG*PNLNLQMEYL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_1648 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 12 parental genes, and 27 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000016875	1 retrocopy	retro_amel_954,
Bos taurus	ENSBTAG00000036282	4 retrocopies	retro_btau_725, retro_btau_726, retro_btau_727, retro_btau_728,
Choloepus hoffmanni	ENSCHOG00000007788	1 retrocopy	retro_chof_1648 ,
Dasypus novemcinctus	ENSDNOG00000011546	1 retrocopy	retro_dnov_1033,
Dipodomys ordii	ENSDORG00000003005	1 retrocopy	retro_dord_485,
Echinops telfairi	ENSETEG00000000256	2 retrocopies	retro_etel_1338, retro_etel_1789,
Gorilla gorilla	ENSGGOG00000025296	2 retrocopies	retro_ggor_1386, retro_ggor_99,
Microcebus murinus	ENSMICG00000000967	4 retrocopies	retro_mmur_1456, retro_mmur_354, retro_mmur_689, retro_mmur_909,
Oryctolagus cuniculus	ENSOCUG00000017824	2 retrocopies	retro_ocun_1782, retro_ocun_498,
Otolemur garnettii	ENSOGAG00000004383	1 retrocopy	retro_ogar_2065,
Pan troglodytes	ENSPTRG00000005266	1 retrocopy	retro_ptro_1270,
Tupaia belangeri	ENSTBEG00000008887	7 retrocopies	retro_tbel_1515, retro_tbel_2047, retro_tbel_2126, retro_tbel_302, retro_tbel_3391, retro_tbel_3721, retro_tbel_972,