RetrogeneDB ID: retro_cpor_44

Retrocopy location

• Organism: Guinea Pig (Cavia porcellus)
• Coordinates: scaffold_20:12514168..12515188(+)
• Located in intron of: ENSCPOG00000010736

Retrocopy information

• Ensembl ID: ENSCPOG00000022251
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCPOG00000010797
• Aliases: None
• Description: None

Sequence

>retro_cpor_44
ATGGCAGCATCTGAAGATGGGTTACAGCTACCTCGACTTCCCGAGCTGTTCGAATCCAGCCAACAGCTTCTGGAGGAAGT
AGAAGTAATGGATGAACCCACTGGCTCCAGGACAATCCAGGATAAAGTGTGCAAGGGACTAGACCTACTTGAGCAGGCTG
CTGAAATGTTATCACAGCTCGATTTGTTCAGCCGAAATGAAGATTTAGAAGACATTTGCTCCACTGACCTGAAGTACCTG
ATGGTGCCAGCGTTTCAAGGAGCCCTCACCATGAAACAAGTGAACCCCAGCAAGCGCCTCGATCATTTACAGTGGGCTCG
AGAATATTTTATAAACTACTTAACTCATTGCCATTATTATCACGTGGCAGATTTTGAGCTGCCCAAAACCAAGAACAACA
CAGCTGAAATTAACACTGCTAGTTCCTCTGTGGCCTGTGCTAACCTTGTTGCTATGGCTTCTCAGAGGAAGGCTAAAATA
GAGAGATACAAGCAGAAGAAAGAGGTGGAGCAGAGGTTGTCTGCACTGAAATCTGCTGTGGAAAGTGGTCAAGCAGATGA
TGAGCAAGTTCGTGAATATTATCTCCTTCATCTTCGGAGGTGGATTGGAATCAGCTTAGAAGAAGTTGAGTGCATTGACC
AGGAAATAAAGATTCTGAGAGAAAAAGACTCTTCAAGAGAAGCATCAACTTCTCACTCATCTCTTCAGGACAGACCTCCC
CTGAAATCCTTCATACTCACTCGGGACAACACCCAAGCCAAAGTTTTCGGAGCTGGTTATCCAAGTCTGGCAACTATGAC
CGTGAGTGACTGGTACGAGCAGCACCAGCAATGTGGAGCACTACCAGACCAGGGAATAGCCAAAGCAACATCAGCTGATT
TCAAAAGAGTGGCTCAGCAACAGGAAGATGAAGAAAAGGAAAGAGAGGACAATGAGAAGGTTCTCCACAGAGCACGCGAG
TGGGATGACTGGAAGCACACCCATCCGAGGGGCTACGGCAACCGACAGAACATGGGGTAG

Alignment

ORF - retro_cpor_44 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.38 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MAASEDGLELPRLPELFETSKQLLEEVEVTNEPTGSGTIQDKVFKGLDLLEKAAEMLSQLDLFSRNEDLE
          MAASEDGL.LPRLPELFE.S.QLLEEVEV..EPTGS.TIQDKV.KGLDLLE.AAEMLSQLDLFSRNEDLE
Retrocopy MAASEDGLQLPRLPELFESSQQLLEEVEVMDEPTGSRTIQDKVCKGLDLLEQAAEMLSQLDLFSRNEDLE

Parental  EIASIDLKYLMVPAFQGALTMKQVNPSKRLDHLQRAREHFINYLTQCHYYHVAEFQLPKTNNNTAEKNTA
          .I.S.DLKYLMVPAFQGALTMKQVNPSKRLDHLQ.ARE.FINYLT.CHYYHVA.F.LPKT.NNTAE.NTA
Retrocopy DICSTDLKYLMVPAFQGALTMKQVNPSKRLDHLQWAREYFINYLTHCHYYHVADFELPKTKNNTAEINTA

Parental  SSSVAYANLVTMASQRKAKIERYKQKKEVEHRLSTLKSAVESGQADDEQVREYYLLHLRRWIGISLEEVE
          SSSVA.ANLV.MASQRKAKIERYKQKKEVE.RLS.LKSAVESGQADDEQVREYYLLHLRRWIGISLEEVE
Retrocopy SSSVACANLVAMASQRKAKIERYKQKKEVEQRLSALKSAVESGQADDEQVREYYLLHLRRWIGISLEEVE

Parental  SIDQEIKILREKDSSREASTSHSPLQDRPPVKSFILTRDKAQAKVFGAGYPSLATMTVSDWYEQHRKYGA
          .IDQEIKILREKDSSREASTSHS.LQDRPP.KSFILTRD..QAKVFGAGYPSLATMTVSDWYEQH...GA
Retrocopy CIDQEIKILREKDSSREASTSHSSLQDRPPLKSFILTRDNTQAKVFGAGYPSLATMTVSDWYEQHQQCGA

Parental  LPDQGIAKATSVDFRRVAQQQEDEEKEKEDDEKALHRAREWDDWKDTHPRGYGNRQNMG
          LPDQGIAKATS.DF.RVAQQQEDEEKE.ED.EK.LHRAREWDDWK.THPRGYGNRQNMG
Retrocopy LPDQGIAKATSADFKRVAQQQEDEEKEREDNEKVLHRAREWDDWKHTHPRGYGNRQNMG

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.40 RPM	15.87 RPM
SRP017611_kidney	0.10 RPM	19.37 RPM
SRP017611_liver	0.00 RPM	10.01 RPM
SRP040447_lung	0.18 RPM	19.47 RPM
SRP040447_skeletal_muscle	0.03 RPM	21.08 RPM

ChIP-Seq

Cavia porcellus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cpor_44 retrocopy.

TSS

Cavia porcellus was not studied using FANTOM5 data.

Lab

retro_cpor_44 was not experimentally validated.

Homology

Retrocopy orthology:

Cavia porcellus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 48 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000007797	1 retrocopy	retro_btau_215,
Choloepus hoffmanni	ENSCHOG00000013654	3 retrocopies	retro_chof_1523, retro_chof_2206, retro_chof_438,
Callithrix jacchus	ENSCJAG00000012525	6 retrocopies	retro_cjac_111, retro_cjac_1225, retro_cjac_2278, retro_cjac_2968, retro_cjac_3417, retro_cjac_47,
Cavia porcellus	ENSCPOG00000010797	1 retrocopy	retro_cpor_44 ,
Dasypus novemcinctus	ENSDNOG00000014731	5 retrocopies	retro_dnov_1160, retro_dnov_2029, retro_dnov_2340, retro_dnov_2380, retro_dnov_678,
Echinops telfairi	ENSETEG00000003397	1 retrocopy	retro_etel_1637,
Felis catus	ENSFCAG00000029688	1 retrocopy	retro_fcat_23,
Homo sapiens	ENSG00000089289	5 retrocopies	retro_hsap_1317, retro_hsap_1848, retro_hsap_2766, retro_hsap_2919, retro_hsap_3059,
Gorilla gorilla	ENSGGOG00000027795	2 retrocopies	retro_ggor_112, retro_ggor_2020,
Myotis lucifugus	ENSMLUG00000004179	1 retrocopy	retro_mluc_316,
Macaca mulatta	ENSMMUG00000013929	2 retrocopies	retro_mmul_1545, retro_mmul_31,
Mus musculus	ENSMUSG00000031221	1 retrocopy	retro_mmus_169,
Nomascus leucogenys	ENSNLEG00000000747	5 retrocopies	retro_nleu_1399, retro_nleu_1653, retro_nleu_2334, retro_nleu_671, retro_nleu_828,
Otolemur garnettii	ENSOGAG00000011797	1 retrocopy	retro_ogar_110,
Pongo abelii	ENSPPYG00000020435	4 retrocopies	retro_pabe_1099, retro_pabe_1451, retro_pabe_2245, retro_pabe_2533,
Pan troglodytes	ENSPTRG00000021990	5 retrocopies	retro_ptro_1233, retro_ptro_1873, retro_ptro_1973, retro_ptro_1982, retro_ptro_901,
Pteropus vampyrus	ENSPVAG00000005483	1 retrocopy	retro_pvam_1462,
Rattus norvegicus	ENSRNOG00000026267	1 retrocopy	retro_rnor_311,
Tarsius syrichta	ENSTSYG00000006214	2 retrocopies	retro_tsyr_1537, retro_tsyr_2131,