RetrogeneDB ID: retro_mmul_1923

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 5:156941474..156942035(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: CHORDC1
• Ensembl ID: ENSMMUG00000005209
• Aliases: None
• Description: cysteine and histidine-rich domain-containing protein 1 [Source:RefSeq peptide;Acc:NP_001244685]

Sequence

>retro_mmul_1923
ATGTCATTGCTTAGCAATAACCAGGCTGCAGTCAGTGCTTCAATCTAGGGGCCAATTCCAATGACGCTTGTTCATCCCAC
CCAGATGTTCCAGTCTTTGTGATATATTAGAAGGTTGGTCTCACTGTAAGAGAAGCACAACTGATTTTTCTGATTTCTTA
TGCGTTGCAGGCTGTACTACAGGTAAACGGAAGAGTGAGAAGTCACCTGAGCCAGTCAAACCTGAAGTCAAGACTACAGA
AAAGAAAGAACTATTTGAATCAAAACCCAAATTTCAGGAGCTCGTGATTCAAGCCTCTAATCCAGCAGAATCAAAAAAAA
AGGCCAAGTCCAAATAAACCAGTGACAAACTCGAAACTAAAAAGCATCTGCCTGCCTAAAACAAGCACTTGATAAACTGT
CATAAGGGAATGAATATGATAAGAAAGAAGACAGTGAAGAAATCAAGATTGGGAACTCACGTGAAAATGGAGGGTGTTCA
AAGATATCTCAGGGTCCACAAAATCCAGAGTAAGCCTGTGTCTATCATTCTGTAGCAGCTATTTTCCACAAGGAGATGAA
A

Alignment

ORF - retro_mmul_1923 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 62.37 %
• Parental protein coverage: 57.93 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  MALLCYNR-GCGQRFDPETNSDDACTYHPGVPVFH-DALKGWSCCKRRTTDFSDFLSIVGCTKGRHNSEK
          M.LL..N..GC.Q.F....NS.DAC..HP.VPVF..D.L.GWS.CKR.TTDFSDFL...GCT.G...SEK
Retrocopy MSLLSNNQ<GCSQCFNLGANSNDACSSHPDVPVFV<DILEGWSHCKRSTTDFSDFLCVAGCTTGKRKSEK

Parental  PPEPVKPEVKTTEKKELSELKPKFQEHIIQAPKPVE-AIKRPSPDEPMTNLEL-KISASLKQALDKLKLS
          .PEPVKPEVKTTEKKEL.E.KPKFQE..IQA..P.E.....PSP..P.TN..L.K.SA.LKQALD..KLS
Retrocopy SPEPVKPEVKTTEKKELFESKPKFQELVIQASNPAE>XXXXPSPNKPVTNSKL>KASACLKQALD--KLS

Parental  SGNEEDKKEEDNDEIKIGTSCKNGGCSKTYRGLESLEEVCVYHSGVPIFHEGMK
          .GNE.DKK.ED..EIKIG.S..NGGCSK...G....E..CVYHS...IFH..MK
Retrocopy *GNEYDKK-EDSEEIKIGNSRENGGCSKISQGPQNPE*ACVYHSVAAIFHKEMK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	22.19 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	24.83 RPM
SRP007412_cerebellum	0.00 RPM	16.27 RPM
SRP007412_heart	0.00 RPM	15.43 RPM
SRP007412_kidney	0.00 RPM	12.32 RPM
SRP007412_liver	0.00 RPM	4.16 RPM
SRP007412_testis	0.00 RPM	37.77 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_1923 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_1923 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_1923 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 14 parental genes, and 33 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000000903	4 retrocopies	retro_cjac_2220, retro_cjac_2927, retro_cjac_4147, retro_cjac_815,
Echinops telfairi	ENSETEG00000013104	2 retrocopies	retro_etel_1713, retro_etel_1860,
Felis catus	ENSFCAG00000019389	1 retrocopy	retro_fcat_137,
Homo sapiens	ENSG00000110172	3 retrocopies	retro_hsap_1452, retro_hsap_1903, retro_hsap_2252,
Gorilla gorilla	ENSGGOG00000027396	3 retrocopies	retro_ggor_1117, retro_ggor_1118, retro_ggor_1679,
Loxodonta africana	ENSLAFG00000017340	1 retrocopy	retro_lafr_401,
Macaca mulatta	ENSMMUG00000005209	2 retrocopies	retro_mmul_1024, retro_mmul_1923 ,
Nomascus leucogenys	ENSNLEG00000007079	5 retrocopies	retro_nleu_1085, retro_nleu_1232, retro_nleu_1320, retro_nleu_752, retro_nleu_981,
Oryctolagus cuniculus	ENSOCUG00000014147	1 retrocopy	retro_ocun_1595,
Otolemur garnettii	ENSOGAG00000003523	1 retrocopy	retro_ogar_2724,
Pongo abelii	ENSPPYG00000003764	5 retrocopies	retro_pabe_1199, retro_pabe_1554, retro_pabe_1734, retro_pabe_1959, retro_pabe_461,
Pan troglodytes	ENSPTRG00000004164	3 retrocopies	retro_ptro_1253, retro_ptro_1595, retro_ptro_988,
Tupaia belangeri	ENSTBEG00000002910	1 retrocopy	retro_tbel_2891,
Tarsius syrichta	ENSTSYG00000004205	1 retrocopy	retro_tsyr_1581,