RetrogeneDB ID: retro_mmus_3632

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: X:68319640..68320250(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMUSG00000083912
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: Ranbp1
• Ensembl ID: ENSMUSG00000005732
• Aliases: None
• Description: RAN binding protein 1 [Source:MGI Symbol;Acc:MGI:96269]

Sequence

>retro_mmus_3632
ATGGCTGCTGCCAAGGACAGTCACGAGGACCATGGTACTTCCACAGAGAATGCAGATGATTCGAATCATGACCCCCCAGT
TCGAGCCAATAGTTTCTCTTCCTGAGCAAGAAATTAAAACGCTGGAGGAAGATGAAGAGGAACTTTGTAAGATGCTTGCA
AAGCTGTTCCGGTTTGTGTCAGAGAATGACCTCCCATAATGGAAGGAGCAAGGCACTGGAGACGTCAGGCTTCTGAAGCA
CAAGGAGAAAGGGACCATCCGCCTTCTCACAAGGAGGGACAAAACCTTGAAGATATGTGCCAACCATTATATCACACCAC
TGATGGAGCTGAAGCTGAATGCTGGCAGTGATAGAGCCTGGGTCTGGAATACCCACGCCGACATTGCTGACGAGTGCCCC
AAGCCTGAACTGCTCGCCATCCACTTCCTAAATGTTGAGAATGCACAAAAGTTCAAAACAAAGTTTGAAGAATGCAGGAA
AGAAATTGAAGAGAGAGAAAAGGAAGGACCAGGCAAAAATGATAATGCCGAAAAGGTGGCCAAGAAGCTGAAAGCCCTTT
CAGTGAGGGAGGCCATAGATGAGGCTGAAGAGAAGTCTGAGGAGAAGCAA

Alignment

ORF - retro_mmus_3632 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 90.2 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MAAAKDSHEDHDTSTENADESNHD-PQFEPIVSLPEQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKE
          MAAAKDSHEDH.TSTENAD.SNHD.PQFEPIVSLPEQEIKTLEEDEEEL.KM.AKLFRF.SENDLP.WKE
Retrocopy MAAAKDSHEDHGTSTENADDSNHD>PQFEPIVSLPEQEIKTLEEDEEELCKMLAKLFRFVSENDLP*WKE

Parental  RGTGDVKLLKHKEKGTIRLLMRRDKTLKICANHYITPMMELKPNAGSDRAWVWNTHADFADECPKPELLA
          .GTGDV.LLKHKEKGTIRLL.RRDKTLKICANHYITP.MELK.NAGSDRAWVWNTHAD.ADECPKPELLA
Retrocopy QGTGDVRLLKHKEKGTIRLLTRRDKTLKICANHYITPLMELKLNAGSDRAWVWNTHADIADECPKPELLA

Parental  IRFLNAENAQKFKTKFEECRKEIEEREKKGPGKNDNAEKVAEKLEALSVREAREEAEEKSEEKQ
          I.FLN.ENAQKFKTKFEECRKEIEEREK.GPGKNDNAEKVA.KL.ALSVREA..EAEEKSEEKQ
Retrocopy IHFLNVENAQKFKTKFEECRKEIEEREKEGPGKNDNAEKVAKKLKALSVREAIDEAEEKSEEKQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	29.72 RPM
SRP007412_cerebellum	0.00 RPM	25.97 RPM
SRP007412_heart	0.00 RPM	17.12 RPM
SRP007412_kidney	0.00 RPM	21.39 RPM
SRP007412_liver	0.03 RPM	16.06 RPM
SRP007412_testis	0.00 RPM	42.08 RPM

ChIP-Seq

RNA Polymerase II activity near the 5' end of retro_mmus_3632 was not detected

EST

No EST(s) were mapped for retro_mmus_3632 retrocopy.

TSS

No TSS is located nearby retro_mmus_3632 retrocopy 5' end.

Lab

retro_mmus_3632 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_3632 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 17 parental genes, and 40 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000010749	1 retrocopy	retro_cjac_2619,
Cavia porcellus	ENSCPOG00000002962	1 retrocopy	retro_cpor_1249,
Dipodomys ordii	ENSDORG00000011317	2 retrocopies	retro_dord_241, retro_dord_602,
Echinops telfairi	ENSETEG00000015996	2 retrocopies	retro_etel_1018, retro_etel_1518,
Homo sapiens	ENSG00000099901	2 retrocopies	retro_hsap_1727, retro_hsap_4797,
Gorilla gorilla	ENSGGOG00000000784	1 retrocopy	retro_ggor_170,
Macropus eugenii	ENSMEUG00000016620	8 retrocopies	retro_meug_1064, retro_meug_1553, retro_meug_1670, retro_meug_1795, retro_meug_272, retro_meug_422, retro_meug_657, retro_meug_753,
Myotis lucifugus	ENSMLUG00000017535	1 retrocopy	retro_mluc_1429,
Macaca mulatta	ENSMMUG00000020100	1 retrocopy	retro_mmul_1215,
Monodelphis domestica	ENSMODG00000010312	5 retrocopies	retro_mdom_1290, retro_mdom_1397, retro_mdom_1406, retro_mdom_1996, retro_mdom_288,
Mus musculus	ENSMUSG00000005732	1 retrocopy	retro_mmus_3632 ,
Nomascus leucogenys	ENSNLEG00000005684	2 retrocopies	retro_nleu_2991, retro_nleu_934,
Otolemur garnettii	ENSOGAG00000034333	2 retrocopies	retro_ogar_1428, retro_ogar_2735,
Pongo abelii	ENSPPYG00000011593	4 retrocopies	retro_pabe_1438, retro_pabe_1470, retro_pabe_3731, retro_pabe_943,
Rattus norvegicus	ENSRNOG00000001884	4 retrocopies	retro_rnor_1817, retro_rnor_811, retro_rnor_884, retro_rnor_907,
Sarcophilus harrisii	ENSSHAG00000006873	1 retrocopy	retro_shar_9,
Ictidomys tridecemlineatus	ENSSTOG00000026840	2 retrocopies	retro_itri_1579, retro_itri_345,