RetrogeneDB ID: retro_btau_912

Retrocopy location

• Organism: Cow (Bos taurus)
• Coordinates: 20:5534178..5534589(-)
• Located in intron of: ENSBTAG00000009995

Retrocopy information

• Ensembl ID: ENSBTAG00000045543
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: HRSP12
• Ensembl ID: ENSBTAG00000012595
• Aliases: None
• Description: Ribonuclease UK114 [Source:UniProtKB/Swiss-Prot;Acc:Q3T114]

Sequence

>retro_btau_912
ATGTTGTCTTTGGTCAGAAAGATAATCAGCACCACGAAAGCCCCCGCGGCCACTGGTCCCTACAGTCAGGCTGTGTTAGT
CGACAGGACCATTTACATTTCAGCACAGCTAGGCATGGACCCTGCAAGTGGACAGCTTGTGCCAGGAGGGGTGGCAGAAG
AGGCTAAACAGGCTCTTACAAACATAGGTGAAATTCTGAAAGCAGCAGGCTATGACTTCACGAATGTGGTAAAAGCAACT
GTTTTGCTGGCTGACATAAATGACTTCAGTACTGTCAACGATGTCTACAAACTATATTTTCAGAGTAGTTTTCCTGCAAG
AGCTGCTTACCAGGTTGCTGCTTTGCCCAAAGGAGGCTGTGTTGAGACCGAAGCAATAGCTGTGCAAGGACCTCTCACGA
CAGCATCGCTC

Alignment

ORF - retro_btau_912 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 94.16 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MSSLVRKIISTAKAPAAIGPYSQAVLVDRTIYISGQLGMDPASGQLVPGGVAEEAKQALTNIGEILKAAG
          M.SLVRKIIST.KAPAA.GPYSQAVLVDRTIYIS.QLGMDPASGQLVPGGVAEEAKQALTNIGEILKAAG
Retrocopy MLSLVRKIISTTKAPAATGPYSQAVLVDRTIYISAQLGMDPASGQLVPGGVAEEAKQALTNIGEILKAAG

Parental  CDFTNVVKATVLLADINDFSTVNDVYKQYFQSSFPARAAYQVAALPKGGRVEIEAIAVQGPLTTASL
          .DFTNVVKATVLLADINDFSTVNDVYK.YFQSSFPARAAYQVAALPKGG.VE.EAIAVQGPLTTASL
Retrocopy YDFTNVVKATVLLADINDFSTVNDVYKLYFQSSFPARAAYQVAALPKGGCVETEAIAVQGPLTTASL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
ERP005899_liver	0.07 RPM	155.58 RPM
ERP005899_muscle	0.05 RPM	15.36 RPM
SRP017611_brain	0.05 RPM	17.95 RPM
SRP017611_kidney	0.24 RPM	193.34 RPM
SRP017611_liver	0.15 RPM	41.00 RPM
SRP030211_testis	0.04 RPM	6.07 RPM

ChIP-Seq

Bos taurus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_btau_912 retrocopy.

TSS

Bos taurus was not studied using FANTOM5 data.

Lab

retro_btau_912 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_btau_912 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 24 parental genes, and 75 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000000575	1 retrocopy	retro_amel_1033,
Bos taurus	ENSBTAG00000012595	5 retrocopies	retro_btau_1068, retro_btau_1145, retro_btau_1328, retro_btau_771, retro_btau_912 ,
Canis familiaris	ENSCAFG00000030250	1 retrocopy	retro_cfam_668,
Choloepus hoffmanni	ENSCHOG00000001278	8 retrocopies	retro_chof_133, retro_chof_1972, retro_chof_2434, retro_chof_2503, retro_chof_2676, retro_chof_380, retro_chof_515, retro_chof_757,
Callithrix jacchus	ENSCJAG00000015560	2 retrocopies	retro_cjac_1702, retro_cjac_465,
Dasypus novemcinctus	ENSDNOG00000025138	3 retrocopies	retro_dnov_1155, retro_dnov_224, retro_dnov_793,
Felis catus	ENSFCAG00000002167	1 retrocopy	retro_fcat_624,
Homo sapiens	ENSG00000132541	3 retrocopies	retro_hsap_1502, retro_hsap_284, retro_hsap_3022,
Gorilla gorilla	ENSGGOG00000001185	1 retrocopy	retro_ggor_1153,
Loxodonta africana	ENSLAFG00000002078	1 retrocopy	retro_lafr_437,
Microcebus murinus	ENSMICG00000004356	13 retrocopies	retro_mmur_1096, retro_mmur_1206, retro_mmur_1323, retro_mmur_209, retro_mmur_222, retro_mmur_364, retro_mmur_533, retro_mmur_589, retro_mmur_597, retro_mmur_603, retro_mmur_79, retro_mmur_870, retro_mmur_97,
Macaca mulatta	ENSMMUG00000011825	2 retrocopies	retro_mmul_558, retro_mmul_88,
Monodelphis domestica	ENSMODG00000006575	1 retrocopy	retro_mdom_319,
Mustela putorius furo	ENSMPUG00000015253	1 retrocopy	retro_mputfur_1449,
Nomascus leucogenys	ENSNLEG00000002485	3 retrocopies	retro_nleu_1721, retro_nleu_3065, retro_nleu_837,
Ornithorhynchus anatinus	ENSOANG00000021532	1 retrocopy	retro_oana_33,
Otolemur garnettii	ENSOGAG00000001465	3 retrocopies	retro_ogar_2308, retro_ogar_2951, retro_ogar_552,
Pongo abelii	ENSPPYG00000018776	3 retrocopies	retro_pabe_1253, retro_pabe_2504, retro_pabe_387,
Pan troglodytes	ENSPTRG00000020457	3 retrocopies	retro_ptro_1019, retro_ptro_2040, retro_ptro_234,
Sus scrofa	ENSSSCG00000006079	1 retrocopy	retro_sscr_834,
Ictidomys tridecemlineatus	ENSSTOG00000011452	4 retrocopies	retro_itri_1591, retro_itri_192, retro_itri_605, retro_itri_894,
Tarsius syrichta	ENSTSYG00000003085	6 retrocopies	retro_tsyr_120, retro_tsyr_1541, retro_tsyr_226, retro_tsyr_373, retro_tsyr_624, retro_tsyr_798,
Tursiops truncatus	ENSTTRG00000016066	5 retrocopies	retro_ttru_1282, retro_ttru_1589, retro_ttru_1626, retro_ttru_369, retro_ttru_909,
Vicugna pacos	ENSVPAG00000008277	3 retrocopies	retro_vpac_30, retro_vpac_358, retro_vpac_89,