RetrogeneDB ID: retro_mmus_2457

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 4:47071589..47071947(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMUSG00000084199
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: Rps17
• Ensembl ID: ENSMUSG00000061787
• Aliases: None
• Description: ribosomal protein S17 [Source:MGI Symbol;Acc:MGI:1309526]

Sequence

>retro_mmus_2457
ATGGGACATGTTCACACCAAGATCGTGAAGAAAGCGGCACGGGTGATCATCGAGAAGTACTACATGCGCCTGGGTAATGA
CTTCCACACCAACAAGCGCGTGTGAGAGGAGATCGCCATTATCCCCAGCAAGAAGCTTTGGAACAAGATAGCCGGCTACT
TCACGCATCTGATGATCGGATTCAGAGAGGTCCTGTGAGAGGTAGCTCTTTCAAGTTGCAGGAAGAAGAGAGAGAGAGGA
GAGCTGATTACGTTCCTGAGGTCTCAGCCCTAGATCAGGAGATCACTGAGGTGGATCCCGACACCAGGAGATGCTGACGC
TTCTGGACTTGGGCAGTCTCTCTAACCTGCACGTCACT

Alignment

ORF - retro_mmus_2457 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 79.51 %
• Parental protein coverage: 88.89 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLM-KRIQRGPVRGI
          MG.V.TK.VKKAARVIIEKYY.RLGNDFHTNKRV.EEIAIIPSKKL.NKIAGY.THLM..RIQRGPVRG.
Retrocopy MGHVHTKIVKKAARVIIEKYYMRLGNDFHTNKRV*EEIAIIPSKKLWNKIAGYFTHLM<DRIQRGPVRGS

Parental  SIKLQEEERERRDNYVPEVSALDQEIIEVDPDTK-EMLKLLDFGSLSNLQVT
          S.KLQE........YVPEVSALDQEI.EVDPDT..EML.LLD.GSLSNL.VT
Retrocopy SFKLQEXXXXXXXDYVPEVSALDQEITEVDPDTR<EMLTLLDLGSLSNLHVT

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.02 RPM	44.76 RPM
SRP007412_cerebellum	0.00 RPM	37.91 RPM
SRP007412_heart	0.00 RPM	90.78 RPM
SRP007412_kidney	0.02 RPM	88.05 RPM
SRP007412_liver	0.00 RPM	73.27 RPM
SRP007412_testis	0.00 RPM	57.40 RPM

ChIP-Seq

RNA Polymerase II actvity near the 5' end of retro_mmus_2457 was not detected

EST

No EST(s) were mapped for retro_mmus_2457 retrocopy.

TSS

No TSS is located nearby retro_mmus_2457 retrocopy 5' end.

Lab

retro_mmus_2457 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_2457 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 22 parental genes, and 129 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000012225	4 retrocopies	retro_acar_128, retro_acar_154, retro_acar_177, retro_acar_81,
Bos taurus	ENSBTAG00000000622	4 retrocopies	retro_btau_1014, retro_btau_568, retro_btau_731, retro_btau_884,
Canis familiaris	ENSCAFG00000013053	9 retrocopies	retro_cfam_1032, retro_cfam_1234, retro_cfam_1680, retro_cfam_1707, retro_cfam_217, retro_cfam_240, retro_cfam_307, retro_cfam_491, retro_cfam_82,
Dasypus novemcinctus	ENSDNOG00000012633	6 retrocopies	retro_dnov_1183, retro_dnov_1296, retro_dnov_2140, retro_dnov_2636, retro_dnov_416, retro_dnov_673,
Equus caballus	ENSECAG00000024902	1 retrocopy	retro_ecab_92,
Echinops telfairi	ENSETEG00000008035	10 retrocopies	retro_etel_1279, retro_etel_1375, retro_etel_1501, retro_etel_1658, retro_etel_1950, retro_etel_592, retro_etel_619, retro_etel_673, retro_etel_851, retro_etel_984,
Felis catus	ENSFCAG00000002358	7 retrocopies	retro_fcat_1060, retro_fcat_1354, retro_fcat_1419, retro_fcat_1549, retro_fcat_288, retro_fcat_436, retro_fcat_710,
Homo sapiens	ENSG00000182774	11 retrocopies	retro_hsap_1516, retro_hsap_1743, retro_hsap_2150, retro_hsap_2702, retro_hsap_3172, retro_hsap_3477, retro_hsap_3570, retro_hsap_3588, retro_hsap_3719, retro_hsap_464, retro_hsap_925,
Homo sapiens	ENSG00000184779	5 retrocopies	retro_hsap_2559, retro_hsap_2854, retro_hsap_3233, retro_hsap_3909, retro_hsap_4110,
Myotis lucifugus	ENSMLUG00000022830	3 retrocopies	retro_mluc_1202, retro_mluc_1347, retro_mluc_1949,
Macaca mulatta	ENSMMUG00000011327	6 retrocopies	retro_mmul_116, retro_mmul_194, retro_mmul_200, retro_mmul_266, retro_mmul_67, retro_mmul_99,
Monodelphis domestica	ENSMODG00000002011	9 retrocopies	retro_mdom_1482, retro_mdom_1923, retro_mdom_1928, retro_mdom_330, retro_mdom_342, retro_mdom_422, retro_mdom_425, retro_mdom_645, retro_mdom_762,
Mus musculus	ENSMUSG00000061787	12 retrocopies	retro_mmus_1095, retro_mmus_1396, retro_mmus_1630, retro_mmus_2457 , retro_mmus_2805, retro_mmus_2852, retro_mmus_3382, retro_mmus_3608, retro_mmus_549, retro_mmus_697, retro_mmus_909, retro_mmus_972,
Oryctolagus cuniculus	ENSOCUG00000006370	1 retrocopy	retro_ocun_90,
Otolemur garnettii	ENSOGAG00000024107	16 retrocopies	retro_ogar_1342, retro_ogar_14, retro_ogar_1632, retro_ogar_174, retro_ogar_1902, retro_ogar_2146, retro_ogar_2221, retro_ogar_2392, retro_ogar_2547, retro_ogar_2686, retro_ogar_2744, retro_ogar_3059, retro_ogar_439, retro_ogar_579, retro_ogar_647, retro_ogar_752,
Pongo abelii	ENSPPYG00000006888	3 retrocopies	retro_pabe_108, retro_pabe_194, retro_pabe_72,
Pteropus vampyrus	ENSPVAG00000012022	8 retrocopies	retro_pvam_1172, retro_pvam_1263, retro_pvam_332, retro_pvam_411, retro_pvam_413, retro_pvam_603, retro_pvam_739, retro_pvam_823,
Rattus norvegicus	ENSRNOG00000019106	6 retrocopies	retro_rnor_19, retro_rnor_23, retro_rnor_276, retro_rnor_285, retro_rnor_289, retro_rnor_84,
Sorex araneus	ENSSARG00000013001	2 retrocopies	retro_sara_246, retro_sara_388,
Sus scrofa	ENSSSCG00000027358	2 retrocopies	retro_sscr_408, retro_sscr_91,
Ictidomys tridecemlineatus	ENSSTOG00000006298	2 retrocopies	retro_itri_769, retro_itri_841,
Tursiops truncatus	ENSTTRG00000013011	2 retrocopies	retro_ttru_1467, retro_ttru_683,