RetrogeneDB ID: retro_cjac_1964

Retrocopy location

• Organism: Marmoset (Callithrix jacchus)
• Coordinates: 2:141661914..141662772(-)
• Located in intron of: ENSCJAG00000015704

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCJAG00000015267
• Aliases: None
• Description: None

Sequence

>retro_cjac_1964
GGGCTGATGGGGGCCGGAGGCTCTGAGGGCCCAGGGATGGGACACTGCAGTGGCTTTTGTGGAGGCTTTGGCAGTGGCAT
CCAGAGCCAGGATCATGGTCATGGTCAGAGTCAGGGCTGAAGCCGCAGGGCTCACAGAGGCAAGGACAAGGACAAGGAGT
GGATGCCCATTACCAAGCTGGGCCGCCTGGTCAAGGACATGAAGATGAAATTCCTGGAGGAGATCTATCTTTTCTCCCTG
CCCATCAAGGAGTCTGAGATCATTGACTTTTTTCTGAGAGCTCTCTTAAGGATGAGGTTTTGAAGATTATGCTGGTGCAG
AAGCAGACTTGTGCTGACCAGCACACCAGGTTCAAGGGGTTTGTTGCCAGCAGGGACTACAATGGCTATACTGGTCTGGG
TGTTAGGTGCTCCAACGAAGTGGCCACTACCATCCATGAGGCCATCATCCTGGCCAAGCTCTCCACTGTCCCCGTGCACA
AGGCTACTGGGGGAACAAGACTGGCAAGCCCCATAGCATCCCTTGCAAGGTGACAGGCCACTGCAGCTCTGTGCTGGTGA
CCTCATCCCTGTGCCCAGGGGCACTGGCATCATCTCAGCCTCCATGCCCAAGAAGCTGCTGCTGATGACTGGTATCAATG
ACTGCTAAACCTCAGCCAGGGGTTGCACGGCCACCCTGGGCAACTTTGCCATGGCCACCTTCAATGCCATCTCTAAGACT
TACAGCTACCTGACTCCTGACCTCTGGAAGAAGACTATATTCACCAAGTCTCCCTATCAGGAATTCACTGACCACCCAAT
CAAGACCCACACCAGAGTCTTCATGCAGAGGACCCAGGTTCCTGCTGTAGCTACAACA

Alignment

ORF - retro_cjac_1964 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 75.26 %
• Parental protein coverage: 98.29 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  GAAGAPGGPGGPGMGNRGGFRGGFGSGIRGRGRGRGRGRGRGRGARGGKAEDKEWMPVTKLGRLVKDMKI
          G..GA.GG..GPGMG...GF.GGFGSGI.....G.G...G..R.A..GK..DKEWMP.TKLGRLVKDMK.
Retrocopy GLMGA-GGSEGPGMGHCSGFCGGFGSGIQSQDHGHGQSQG*SRRAHRGKDKDKEWMPITKLGRLVKDMKM

Parental  KSLEEIYLFSLPIKESEIIDFFLGA-SLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCS
          K.LEEIYLFSLPIKESEIIDFFL.A.SLKDEVLKIM.VQKQT.A.Q.TRFK.FVA..DYNG..GLGV.CS
Retrocopy KFLEEIYLFSLPIKESEIIDFFLRA<SLKDEVLKIMLVQKQTCADQHTRFKGFVASRDYNGYTGLGVRCS

Parental  KEVATAIRGAIILAKLSIVPVRR-GYWGNKIGKPHTVPCKVTGRCGSVLVR-LIPAPRGTGIVSAPVPKK
          .EVAT.I..AIILAKLS.VPV...GYWGNK.GKPH..PCKVTG.C.SVLV..LIP.PRGTGI.SA..PKK
Retrocopy NEVATTIHEAIILAKLSTVPVHK<GYWGNKTGKPHSIPCKVTGHCSSVLVT<LIPVPRGTGIISASMPKK

Parental  LLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHTRVSV
          LL.M.GI.DC.TSARGCTATLGNFA.ATF.AISKTYSYLTPDLWK.T.FTKSPYQEFTDH..KTHTRV..
Retrocopy LLLMTGINDC*TSARGCTATLGNFAMATFNAISKTYSYLTPDLWKKTIFTKSPYQEFTDHPIKTHTRVFM

Parental  QRTQAPAVATT
          QRTQ.PAVATT
Retrocopy QRTQVPAVATT

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP051959_colon	0.20 RPM	103.33 RPM
SRP051959_heart	0.21 RPM	66.13 RPM
SRP051959_kidney	0.11 RPM	86.90 RPM
SRP051959_liver	0.00 RPM	169.21 RPM
SRP051959_lung	0.07 RPM	76.34 RPM
SRP051959_lymph_node	0.07 RPM	130.47 RPM
SRP051959_skeletal_muscle	0.02 RPM	155.73 RPM
SRP051959_spleen	0.02 RPM	120.76 RPM

ChIP-Seq

Callithrix jacchus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cjac_1964 retrocopy.

TSS

Callithrix jacchus was not studied using FANTOM5 data.

Lab

retro_cjac_1964 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cjac_1964 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3182

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Parental genes homology:

Parental genes homology involve 8 parental genes, and 88 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000002549	1 retrocopy	retro_acar_57,
Callithrix jacchus	ENSCJAG00000015267	15 retrocopies	retro_cjac_1482, retro_cjac_1585, retro_cjac_1609, retro_cjac_1712, retro_cjac_1964 , retro_cjac_2201, retro_cjac_2255, retro_cjac_2284, retro_cjac_2361, retro_cjac_2493, retro_cjac_2620, retro_cjac_274, retro_cjac_317, retro_cjac_3741, retro_cjac_4194,
Felis catus	ENSFCAG00000029191	6 retrocopies	retro_fcat_1245, retro_fcat_1328, retro_fcat_1606, retro_fcat_1610, retro_fcat_1737, retro_fcat_517,
Macropus eugenii	ENSMEUG00000004508	2 retrocopies	retro_meug_156, retro_meug_2103,
Microcebus murinus	ENSMICG00000012765	28 retrocopies	retro_mmur_1192, retro_mmur_1273, retro_mmur_1283, retro_mmur_1296, retro_mmur_1407, retro_mmur_1417, retro_mmur_1440, retro_mmur_153, retro_mmur_1613, retro_mmur_205, retro_mmur_210, retro_mmur_226, retro_mmur_230, retro_mmur_259, retro_mmur_266, retro_mmur_463, retro_mmur_672, retro_mmur_698, retro_mmur_742, retro_mmur_802, retro_mmur_824, retro_mmur_829, retro_mmur_875, retro_mmur_953, retro_mmur_966, retro_mmur_969, retro_mmur_981, retro_mmur_99,
Monodelphis domestica	ENSMODG00000016077	1 retrocopy	retro_mdom_536,
Sarcophilus harrisii	ENSSHAG00000015213	5 retrocopies	retro_shar_186, retro_shar_288, retro_shar_456, retro_shar_525, retro_shar_783,
Tupaia belangeri	ENSTBEG00000006726	30 retrocopies	retro_tbel_1023, retro_tbel_1059, retro_tbel_1105, retro_tbel_1179, retro_tbel_129, retro_tbel_1444, retro_tbel_1545, retro_tbel_1615, retro_tbel_1622, retro_tbel_1786, retro_tbel_1910, retro_tbel_2294, retro_tbel_2749, retro_tbel_2786, retro_tbel_2973, retro_tbel_3179, retro_tbel_3314, retro_tbel_3509, retro_tbel_3523, retro_tbel_3682, retro_tbel_3701, retro_tbel_392, retro_tbel_4373, retro_tbel_463, retro_tbel_4674, retro_tbel_481, retro_tbel_586, retro_tbel_603, retro_tbel_639, retro_tbel_647,