RetrogeneDB ID: retro_nleu_351

Retrocopy location

• Organism: Gibbon (Nomascus leucogenys)
• Coordinates: GL397263.1:18027857..18028973(-)
• Located in intron of: ENSNLEG00000005817

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PTPN2
• Ensembl ID: ENSNLEG00000009074
• Aliases: None
• Description: Tyrosine-protein phosphatase non-receptor type [Source:UniProtKB/TrEMBL;Acc:G1RCW5]

Sequence

>retro_nleu_351
GAAGAGTTGGAAACTCAGCGTCGCTGGCAGCCGCTGTACTTGGAAATTCGAAATGAGTCCCATGACTATCCTCATAGAGT
GGCCAAGTTTCCAGAAAACAGATTTCGAAACAGATACAGAGATCTAAGCCCATATGATCACAGTCGTGTTAAACTGCAAA
ATGCTGAGAATGATTATATTAATGCCAGTTTAGTTGACTTAGAAGAGGCACAAAGGAGTTACATCTTAACACAGGGTCCA
CTTCCTAACACATGCTGCCATTTCTGGCTTATGGTTTGGCAGCAGAAGACCAAAGCAGTTGTCATGCTGAACCGCATTGT
GGAGAAAGAATCGGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAGATGCTGTTTAAAGAAACAGGATTCAGTG
TGAAGCTCTTGTCAGAAGATGTGAAGTTGTATTATACAGTACCTCTACTACAATTAGAAAATATCAATAGTGGTGAAACC
AGAACAATATCTCACTTTCATTATACCACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCTT
GTTTAAAGTGAGAGAATCTGGCTCCTTGAACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCT
CTGGCACCTTCTCTCTGGTAGACACTTGTCTTGTTTTGATGGAAAAAGGAGATGATATTAACATTAAACAAGTGTTATTG
AACATGAGAAAATACCGAATGGGTCTTATTCAGACCCCAGATCAACTGAGATTCTCATACATGGCTATAATAGAAGGAGC
AAAATGTATAAAGGGAGATTCTGGTATACAGAAACGATGGAAAGAACTTTCTAAGGAACACTTATCTCCTGCCTTTGATC
ATTCACCAAACAAAATAATGACTGAAAAATACAATGGGAAGAGAATAGGTCTAGAAAAAGAAAAACTGACAGGTGACCAA
CGTACAGGACCTTCCTCTAAAATGCAAGATACAGTGGAGGAGAACAGTGAGAGTGCTCTACGGAAACGTATTCGAGAGGA
CAGAAAGGCCACCACAGCTCAGAAGGTGCAGCAGATGAAACAGAGGCTAAATGAGAATGAACGAAAAAGAAAAAGG

Alignment

ORF - retro_nleu_351 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 96.51 %
• Parental protein coverage: 89.64 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  EELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIEEA
          EEL.TQRRWQPLYLEIRNESHDYPHRVAKFPENR.RNRYRD.SPYDHSRVKLQNAENDYINASLVD.EEA
Retrocopy EELETQRRWQPLYLEIRNESHDYPHRVAKFPENRFRNRYRDLSPYDHSRVKLQNAENDYINASLVDLEEA

Parental  QRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSED
          QRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSED
Retrocopy QRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSED

Parental  VKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAG
          VK.YYTV.LLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAG
Retrocopy VKLYYTVPLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAG

Parental  IGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSGIQKRW
          IGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSGIQKRW
Retrocopy IGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSGIQKRW

Parental  KELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKA
          KELSKE.LSPAFDHSPNKIMTEKYNG.RIGLE.EKLTGD..TG.SSKMQDT.EENSESALRKRIREDRKA
Retrocopy KELSKEHLSPAFDHSPNKIMTEKYNGKRIGLEKEKLTGDQRTGPSSKMQDTVEENSESALRKRIREDRKA

Parental  TTAQKVQQMKQRLNENERKRKR
          TTAQKVQQMKQRLNENERKRKR
Retrocopy TTAQKVQQMKQRLNENERKRKR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Nomascus leucogenys was not studied using RNA-Seq expression data.

ChIP-Seq

Nomascus leucogenys was not studied using ChIP-Seq data.

EST

Nomascus leucogenys was not studied using EST data.

TSS

Nomascus leucogenys was not studied using FANTOM5 data.

Lab

retro_nleu_351 was not experimentally validated.

Homology

Retrocopy orthology:

Nomascus leucogenys does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 27 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000000867	1 retrocopy	retro_chof_2231,
Callithrix jacchus	ENSCJAG00000005102	1 retrocopy	retro_cjac_1577,
Dasypus novemcinctus	ENSDNOG00000016588	1 retrocopy	retro_dnov_1466,
Erinaceus europaeus	ENSEEUG00000005636	1 retrocopy	retro_eeur_370,
Echinops telfairi	ENSETEG00000005577	2 retrocopies	retro_etel_1743, retro_etel_1942,
Homo sapiens	ENSG00000175354	2 retrocopies	retro_hsap_1186, retro_hsap_480,
Gorilla gorilla	ENSGGOG00000010259	2 retrocopies	retro_ggor_453, retro_ggor_925,
Loxodonta africana	ENSLAFG00000011818	1 retrocopy	retro_lafr_701,
Macropus eugenii	ENSMEUG00000005156	1 retrocopy	retro_meug_653,
Monodelphis domestica	ENSMODG00000021422	1 retrocopy	retro_mdom_1225,
Nomascus leucogenys	ENSNLEG00000000078	5 retrocopies	retro_nleu_1200, retro_nleu_1360, retro_nleu_1654, retro_nleu_522, retro_nleu_561,
Nomascus leucogenys	ENSNLEG00000009074	3 retrocopies	retro_nleu_2112, retro_nleu_351 , retro_nleu_894,
Otolemur garnettii	ENSOGAG00000028605	1 retrocopy	retro_ogar_3429,
Pongo abelii	ENSPPYG00000008983	3 retrocopies	retro_pabe_1077, retro_pabe_1144, retro_pabe_989,
Pan troglodytes	ENSPTRG00000009884	2 retrocopies	retro_ptro_361, retro_ptro_813,