RetrogeneDB ID: retro_ocun_1868

Retrocopy location

• Organism: Rabbit (Oryctolagus cuniculus)
• Coordinates: X:1446520..1447025(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ARF4
• Ensembl ID: ENSOCUG00000000824
• Aliases: None
• Description: ADP-ribosylation factor 4 [Source:HGNC Symbol;Acc:655]

Sequence

>retro_ocun_1868
GGAATATTTTCTGCAAAGCTCCCCAGGGGCCTTTTTGGCAAGAAGGAAATGAGCATCCTTATGATGGGCCTGGATACTGC
AGGGAAGACGATGCAGTTCAAGCTGAAGCTTGGTGAAATTGCGACCACCAGTTTTCAATGTGAAGATGTTGAATAGAAGA
ATGTGGGTATCACCGTGTGGAAGGTGAGTGGCCAAGACAAGATTCGGCCCCGTGGCACCACTACTAACAAAACACCCAAG
GCTTGATCTTTGCTGTGTACAGCAATGACAGAGAACATGTGAACAAGACACAGGAAGAGTTCATGAGGATGCTGGCCGAG
GATGAGCTGCAAGACACGGTCGTCCTGGTGTTTGCCAACAAGCAGGACCTCCCCAGTGCCATGAATGAATCACAGACAAG
ATGGGGCAGCATTCCCTAAGCCACAGGAACTGGTACTTTCGAGCCACCTGTGCCACCAGCAGGGGAGGGCTCTATGAAGG
GCCGCACTGGCTGTCCAGTCAGCTC

Alignment

ORF - retro_ocun_1868 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 58.99 %
• Parental protein coverage: 97.78 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  GLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQ
          G.....L...LFGKK.M.ILM.GLD.AGKT....KLKLGEI.TT.....F..E.VE.KN...TVW.V.GQ
Retrocopy GIFSAKLPRGLFGKKEMSILMMGLDTAGKT-MQFKLKLGEIATT----SFQCEDVE*KNVGITVWKVSGQ

Parental  DKIRPL-WRHYFQNTQGLIFVVDSNDRERIQEGAEELRKILQEDELQDAVLLLFANKQDLPNAMAISE-M
          DKIRP..W.HY.QNTQGLIF.V.SNDRE......EE....L.EDELQD.V.L.FANKQDLP...A..E..
Retrocopy DKIRPR<WHHY*QNTQGLIFAVYSNDREHVNKTQEEFMRMLAEDELQDTVVLVFANKQDLPS--AMNE<I

Parental  TDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNEL
          TDK.G..SL..R.WY..ATCAT...GLYEG..WLS..L
Retrocopy TDKMGQHSLSHRNWYFRATCATSRGGLYEGPHWLSSQL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	85.98 RPM
SRP017611_kidney	0.00 RPM	68.52 RPM
SRP017611_liver	0.00 RPM	30.37 RPM

ChIP-Seq

Oryctolagus cuniculus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ocun_1868 retrocopy.

TSS

Oryctolagus cuniculus was not studied using FANTOM5 data.

Lab

retro_ocun_1868 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ocun_1868 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 28 parental genes, and 49 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000016069	1 retrocopy	retro_btau_542,
Choloepus hoffmanni	ENSCHOG00000006427	4 retrocopies	retro_chof_1024, retro_chof_1807, retro_chof_2368, retro_chof_36,
Ciona intestinalis	ENSCING00000021790	1 retrocopy	retro_cint_10,
Callithrix jacchus	ENSCJAG00000019922	1 retrocopy	retro_cjac_507,
Cavia porcellus	ENSCPOG00000010334	1 retrocopy	retro_cpor_1261,
Dipodomys ordii	ENSDORG00000004312	1 retrocopy	retro_dord_731,
Homo sapiens	ENSG00000168374	2 retrocopies	retro_hsap_1296, retro_hsap_4221,
Gorilla gorilla	ENSGGOG00000000294	1 retrocopy	retro_ggor_1552,
Microcebus murinus	ENSMICG00000002015	3 retrocopies	retro_mmur_1528, retro_mmur_1558, retro_mmur_360,
Myotis lucifugus	ENSMLUG00000007990	1 retrocopy	retro_mluc_2272,
Macaca mulatta	ENSMMUG00000018617	1 retrocopy	retro_mmul_50,
Monodelphis domestica	ENSMODG00000000185	1 retrocopy	retro_mdom_1538,
Nomascus leucogenys	ENSNLEG00000007270	3 retrocopies	retro_nleu_2106, retro_nleu_2703, retro_nleu_2704,
Oryctolagus cuniculus	ENSOCUG00000000824	4 retrocopies	retro_ocun_1007, retro_ocun_1502, retro_ocun_1868 , retro_ocun_987,
Oryctolagus cuniculus	ENSOCUG00000014090	2 retrocopies	retro_ocun_1942, retro_ocun_751,
Oryctolagus cuniculus	ENSOCUG00000023009	1 retrocopy	retro_ocun_1404,
Oryctolagus cuniculus	ENSOCUG00000023198	1 retrocopy	retro_ocun_132,
Oryctolagus cuniculus	ENSOCUG00000023645	2 retrocopies	retro_ocun_1137, retro_ocun_247,
Otolemur garnettii	ENSOGAG00000012034	4 retrocopies	retro_ogar_1407, retro_ogar_1501, retro_ogar_2963, retro_ogar_764,
Pongo abelii	ENSPPYG00000013768	3 retrocopies	retro_pabe_1013, retro_pabe_1075, retro_pabe_3451,
Pan troglodytes	ENSPTRG00000015051	2 retrocopies	retro_ptro_2866, retro_ptro_888,
Rattus norvegicus	ENSRNOG00000012623	2 retrocopies	retro_rnor_1036, retro_rnor_1884,
Sorex araneus	ENSSARG00000009272	1 retrocopy	retro_sara_681,
Ictidomys tridecemlineatus	ENSSTOG00000019470	2 retrocopies	retro_itri_1439, retro_itri_1614,
Tupaia belangeri	ENSTBEG00000007415	1 retrocopy	retro_tbel_2075,
Tarsius syrichta	ENSTSYG00000009748	1 retrocopy	retro_tsyr_2059,
Tursiops truncatus	ENSTTRG00000015381	1 retrocopy	retro_ttru_284,
Vicugna pacos	ENSVPAG00000003891	1 retrocopy	retro_vpac_459,