RetrogeneDB ID: retro_ogar_2144

Retrocopy location

• Organism: Bushbaby (Otolemur garnettii)
• Coordinates: GL873596.1:8714403..8715104(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: YWHAE
• Ensembl ID: ENSOGAG00000006155
• Aliases: None
• Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide [Source:HGNC Symbol;Acc:12851]

Sequence

>retro_ogar_2144
ATGGTGGACTCAAAGAAGAAAGTAGCAGGGGTGGATGTGGAGCTGACAGGTGAAGAAAGAAACCTTCTATCTGTTGCATA
TAAGAATGTGATTGGAGCTAGAAGAGCTTCCTGGAGAATAATCAGCAGCACTGAATAGAAAGAAGAAAACAAGGGAGGAG
AAAACAAACGAAAACTGATTCGGGAATATGGGCAAATGGTTGAGACTGAGCTAAAGTTAATCTGCTGCGCCATTCTGGAT
GTACTGGACAAACACCTCATTCCAGCAGCTAACGCTGGCGAGTCCAAGGTTTTCTACTTCTATAAAATGAAAGGGGACTA
CCACAGGTGTCTGGCAGAATTTGCCACAGGCAATGACAGGAGGGAGGCTGCGGAGAACAGCCTGGTGGCTTATAAAGCTG
CTCGTGATATTGCAATGACAGAACTTCCACCAACGCATCCTAGTCGCTTAGGTCTTGCTCTCAACTTTTCCGTATTCTAC
TATGAAATTCTTAATTCCCCTGACCGTGCCTGCAGGTTAGCAAAAGCGGCTTGGGATGATGCAATTGCAGAACTGGATAC
GCTGAGTGCAGAAAGCTATAAGGACTCTACACTTATCATGCAGTTGTTACGTGATCATCTGACACTATGGACTTCAGACA
TGCAGGGTGACGGTGAAGAGCAGAATAGAGAATGCTGCAGGATGTGGAAGACGACAATCAG

Alignment

ORF - retro_ogar_2144 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.79 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETE
          MV.S.KKVAG.DVELT.EERNLLSVAYKNVIGARRASWRIISS.E.KEENKGGE.K.K.IREY.QMVETE
Retrocopy MVDSKKKVAGVDVELTGEERNLLSVAYKNVIGARRASWRIISSTE*KEENKGGENKRKLIREYGQMVETE

Parental  LKLICCDILDVLDKHLIPAANTGESKVFY-YKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMT
          LKLICC.ILDVLDKHLIPAAN.GESKVFY.YKMKGDYHR.LAEFATGNDR.EAAENSLVAYKAA.DIAMT
Retrocopy LKLICCAILDVLDKHLIPAANAGESKVFYFYKMKGDYHRCLAEFATGNDRREAAENSLVAYKAARDIAMT

Parental  ELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLW
          ELPPTHP.RLGLALNFSVFYYEILNSPDRACRLAKAA.DDAIAELDTLS.ESYKDSTLIMQLLRD.LTLW
Retrocopy ELPPTHPSRLGLALNFSVFYYEILNSPDRACRLAKAAWDDAIAELDTLSAESYKDSTLIMQLLRDHLTLW

Parental  TSDMQGDGEEQNKE-VLQDVEDENQ
          TSDMQGDGEEQN.E..LQDVED.NQ
Retrocopy TSDMQGDGEEQNRE<MLQDVEDDNQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Otolemur garnettii was not studied using RNA-Seq expression data.

ChIP-Seq

Otolemur garnettii was not studied using ChIP-Seq data.

EST

Otolemur garnettii was not studied using EST data.

TSS

Otolemur garnettii was not studied using FANTOM5 data.

Lab

retro_ogar_2144 was not experimentally validated.

Homology

Retrocopy orthology:

Otolemur garnettii does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 16 parental genes, and 40 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000005664	3 retrocopies	retro_btau_1485, retro_btau_372, retro_btau_954,
Choloepus hoffmanni	ENSCHOG00000010861	2 retrocopies	retro_chof_1912, retro_chof_905,
Ciona intestinalis	ENSCING00000023856	1 retrocopy	retro_cint_15,
Ciona savignyi	ENSCSAVG00000011723	2 retrocopies	retro_csav_13, retro_csav_9,
Echinops telfairi	ENSETEG00000012056	2 retrocopies	retro_etel_1762, retro_etel_738,
Homo sapiens	ENSG00000108953	4 retrocopies	retro_hsap_2324, retro_hsap_3739, retro_hsap_3851, retro_hsap_4703,
Gorilla gorilla	ENSGGOG00000016840	1 retrocopy	retro_ggor_2596,
Monodelphis domestica	ENSMODG00000010174	2 retrocopies	retro_mdom_1567, retro_mdom_744,
Nomascus leucogenys	ENSNLEG00000000656	2 retrocopies	retro_nleu_2067, retro_nleu_2868,
Otolemur garnettii	ENSOGAG00000000547	3 retrocopies	retro_ogar_1047, retro_ogar_1732, retro_ogar_39,
Otolemur garnettii	ENSOGAG00000006155	2 retrocopies	retro_ogar_1003, retro_ogar_2144 ,
Otolemur garnettii	ENSOGAG00000008909	3 retrocopies	retro_ogar_122, retro_ogar_1243, retro_ogar_2934,
Pongo abelii	ENSPPYG00000007769	4 retrocopies	retro_pabe_1644, retro_pabe_1646, retro_pabe_2107, retro_pabe_3219,
Pan troglodytes	ENSPTRG00000008521	5 retrocopies	retro_ptro_1697, retro_ptro_2538, retro_ptro_2624, retro_ptro_2626, retro_ptro_2993,
Ictidomys tridecemlineatus	ENSSTOG00000005084	1 retrocopy	retro_itri_1175,
Vicugna pacos	ENSVPAG00000010288	3 retrocopies	retro_vpac_230, retro_vpac_411, retro_vpac_559,