RetrogeneDB ID: retro_btau_758

Retrocopy location

• Organism: Cow (Bos taurus)
• Coordinates: 19:29352213..29352956(+)
• Located in intron of: ENSBTAG00000017815

Retrocopy information

• Ensembl ID: ENSBTAG00000006397
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: RPL7
• Ensembl ID: ENSBTAG00000020139
• Aliases: None
• Description: 60S ribosomal protein L7 [Source:UniProtKB/Swiss-Prot;Acc:Q58DT1]

Sequence

>retro_btau_758
ATGGAGGGTGCAGAAGAGAAGAAAAAGAAGGTTCCTGCTGTGCCAGAAACCCTTAAGAAAAAGTGGAAGAATTTCGCAGA
GCTTAAGATCAAGCGACTGAGAAAGAAGTCTGCCCAAAAGATGCTTCGAAAGGCAAGGAGGAAGCTTATCTATGAAAAAG
CTAAGCATTACCACAAGGAATACAGGCAGATGTACAGAACTGAAATTCGAATGGCTAGGATGGCACGAAAAGCCGGTAAC
TTCTATGTACCCTCGGAACCCAAATTGGCGTTTGTCATCAGGATCAGAGGTACCAATGGTTGAGCCCAAAGGCTTGAAAG
GTGCTGCGGCTCCTTCGCCTCCGGCAGATATTCAGCGGCACCTCTGTGAAGCTCAACAAGGCATCAATTAACATGCTGAG
AATTGTGGAGCCATACATTGCATGGGGGTACCCAAATCTGAAGTCTGTAAATGAACTGATTTACAAGCGTGGTTATGGCA
AAATCAACAAAAAGCGAACTGCCCTGACAGACAACGCATTGATTGCTCGATCTCTTGGGAAATATGGAATCATCTGCATG
GAGGATCTGATTCATGAGATCTATACCGTTGGAAAACGTTTCAAAGAAGCAAACAACTTCCTGTGGCCCTTTAAATTGTC
TTCTCCACGAGGTGGAATGAAGAAAGAGACCACCCATTTTGTAGAAGGTGGAGATGCTGGCAACAGGGAAGACCAGATCA
ACAGGCTTATTAGAAGGATGAAC

Alignment

ORF - retro_btau_758 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 94.78 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MEGAEEKKKKVPAVPETLKKKRKNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIR
          MEGAEEKKKKVPAVPETLKKK.KNFAELKIKRLRKK.AQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIR
Retrocopy MEGAEEKKKKVPAVPETLKKKWKNFAELKIKRLRKKSAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIR

Parental  MARMARKAGNFYVPAEPKLAFVIRIRGING-VSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPY
          MARMARKAGNFYVP.EPKLAFVIRIRG.NG..SPK..KVL.LLRLRQIF.GT.VKLNKASINMLRIVEPY
Retrocopy MARMARKAGNFYVPSEPKLAFVIRIRGTNG<LSPKA*KVLRLLRLRQIFSGTSVKLNKASINMLRIVEPY

Parental  IAWGYPNLKSVNELIYKRGYGKINKKRIALTDNALIARSLGKYGIICMEDLIHEIYTVGKRFKEANNFLW
          IAWGYPNLKSVNELIYKRGYGKINKKR.ALTDNALIARSLGKYGIICMEDLIHEIYTVGKRFKEANNFLW
Retrocopy IAWGYPNLKSVNELIYKRGYGKINKKRTALTDNALIARSLGKYGIICMEDLIHEIYTVGKRFKEANNFLW

Parental  PFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRMN
          PFKLSSPRGGMKK.TTHFVEGGDAGNREDQINRLIRRMN
Retrocopy PFKLSSPRGGMKKETTHFVEGGDAGNREDQINRLIRRMN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
ERP005899_liver	6.27 RPM	178.37 RPM
ERP005899_muscle	0.79 RPM	1258.39 RPM
SRP017611_brain	0.00 RPM	104.47 RPM
SRP017611_kidney	0.83 RPM	269.03 RPM
SRP017611_liver	2.04 RPM	138.03 RPM
SRP030211_testis	0.50 RPM	222.08 RPM

ChIP-Seq

Bos taurus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_btau_758 retrocopy.

TSS

Bos taurus was not studied using FANTOM5 data.

Lab

retro_btau_758 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_btau_758 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 255 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000018478	2 retrocopies	retro_btau_588, retro_btau_816,
Bos taurus	ENSBTAG00000020139	22 retrocopies	retro_btau_1088, retro_btau_1231, retro_btau_1367, retro_btau_1381, retro_btau_1422, retro_btau_1434, retro_btau_1468, retro_btau_1548, retro_btau_1559, retro_btau_1616, retro_btau_1627, retro_btau_1784, retro_btau_1814, retro_btau_304, retro_btau_426, retro_btau_622, retro_btau_668, retro_btau_730, retro_btau_750, retro_btau_758 , retro_btau_863, retro_btau_879,
Callithrix jacchus	ENSCJAG00000007686	1 retrocopy	retro_cjac_105,
Equus caballus	ENSECAG00000009188	1 retrocopy	retro_ecab_35,
Homo sapiens	ENSG00000147604	49 retrocopies	retro_hsap_1001, retro_hsap_1023, retro_hsap_1033, retro_hsap_1034, retro_hsap_1128, retro_hsap_113, retro_hsap_1232, retro_hsap_1281, retro_hsap_1614, retro_hsap_1626, retro_hsap_1844, retro_hsap_1862, retro_hsap_1957, retro_hsap_2008, retro_hsap_203, retro_hsap_2093, retro_hsap_2101, retro_hsap_2588, retro_hsap_2837, retro_hsap_3197, retro_hsap_3204, retro_hsap_3244, retro_hsap_3254, retro_hsap_3356, retro_hsap_3399, retro_hsap_344, retro_hsap_3453, retro_hsap_3493, retro_hsap_3560, retro_hsap_3573, retro_hsap_3625, retro_hsap_3717, retro_hsap_3775, retro_hsap_3883, retro_hsap_3918, retro_hsap_4137, retro_hsap_415, retro_hsap_426, retro_hsap_4306, retro_hsap_4662, retro_hsap_4704, retro_hsap_4718, retro_hsap_4761, retro_hsap_558, retro_hsap_616, retro_hsap_708, retro_hsap_729, retro_hsap_973, retro_hsap_976,
Latimeria chalumnae	ENSLACG00000003571	1 retrocopy	retro_lcha_63,
Macropus eugenii	ENSMEUG00000016319	9 retrocopies	retro_meug_1002, retro_meug_1449, retro_meug_1942, retro_meug_1947, retro_meug_60, retro_meug_760, retro_meug_84, retro_meug_968, retro_meug_99,
Microcebus murinus	ENSMICG00000002880	8 retrocopies	retro_mmur_1170, retro_mmur_1379, retro_mmur_139, retro_mmur_158, retro_mmur_52, retro_mmur_596, retro_mmur_646, retro_mmur_903,
Myotis lucifugus	ENSMLUG00000028550	3 retrocopies	retro_mluc_1478, retro_mluc_2000, retro_mluc_640,
Macaca mulatta	ENSMMUG00000005141	1 retrocopy	retro_mmul_129,
Monodelphis domestica	ENSMODG00000007136	4 retrocopies	retro_mdom_1341, retro_mdom_1998, retro_mdom_371, retro_mdom_66,
Mus musculus	ENSMUSG00000043716	15 retrocopies	retro_mmus_1232, retro_mmus_1345, retro_mmus_1631, retro_mmus_2549, retro_mmus_2562, retro_mmus_2798, retro_mmus_3259, retro_mmus_3305, retro_mmus_3440, retro_mmus_3547, retro_mmus_3552, retro_mmus_3685, retro_mmus_561, retro_mmus_595, retro_mmus_708,
Otolemur garnettii	ENSOGAG00000003903	2 retrocopies	retro_ogar_15, retro_ogar_225,
Pongo abelii	ENSPPYG00000018671	50 retrocopies	retro_pabe_1025, retro_pabe_1061, retro_pabe_1087, retro_pabe_1326, retro_pabe_1454, retro_pabe_1520, retro_pabe_1642, retro_pabe_1677, retro_pabe_1908, retro_pabe_1998, retro_pabe_2004, retro_pabe_2118, retro_pabe_2197, retro_pabe_2348, retro_pabe_2656, retro_pabe_2690, retro_pabe_2762, retro_pabe_2796, retro_pabe_2807, retro_pabe_2808, retro_pabe_2856, retro_pabe_2886, retro_pabe_2936, retro_pabe_2946, retro_pabe_307, retro_pabe_3085, retro_pabe_3117, retro_pabe_3139, retro_pabe_3191, retro_pabe_3414, retro_pabe_3468, retro_pabe_3506, retro_pabe_352, retro_pabe_3622, retro_pabe_3651, retro_pabe_3662, retro_pabe_3669, retro_pabe_3675, retro_pabe_436, retro_pabe_497, retro_pabe_514, retro_pabe_551, retro_pabe_628, retro_pabe_655, retro_pabe_826, retro_pabe_844, retro_pabe_859, retro_pabe_865, retro_pabe_867, retro_pabe_933,
Rattus norvegicus	ENSRNOG00000006992	27 retrocopies	retro_rnor_1018, retro_rnor_1174, retro_rnor_1222, retro_rnor_1233, retro_rnor_1307, retro_rnor_1388, retro_rnor_1466, retro_rnor_1580, retro_rnor_1745, retro_rnor_1916, retro_rnor_1944, retro_rnor_2025, retro_rnor_2028, retro_rnor_2100, retro_rnor_2247, retro_rnor_2304, retro_rnor_2347, retro_rnor_2531, retro_rnor_2715, retro_rnor_2765, retro_rnor_2814, retro_rnor_2824, retro_rnor_530, retro_rnor_666, retro_rnor_911, retro_rnor_929, retro_rnor_977,
Ictidomys tridecemlineatus	ENSSTOG00000004586	18 retrocopies	retro_itri_1025, retro_itri_1080, retro_itri_1358, retro_itri_1375, retro_itri_1412, retro_itri_1430, retro_itri_1464, retro_itri_1593, retro_itri_1776, retro_itri_271, retro_itri_346, retro_itri_349, retro_itri_351, retro_itri_390, retro_itri_534, retro_itri_542, retro_itri_827, retro_itri_917,
Tupaia belangeri	ENSTBEG00000002301	1 retrocopy	retro_tbel_2042,
Tarsius syrichta	ENSTSYG00000006100	25 retrocopies	retro_tsyr_1149, retro_tsyr_1200, retro_tsyr_1293, retro_tsyr_1297, retro_tsyr_1403, retro_tsyr_1598, retro_tsyr_1633, retro_tsyr_1850, retro_tsyr_1891, retro_tsyr_191, retro_tsyr_2109, retro_tsyr_2130, retro_tsyr_344, retro_tsyr_421, retro_tsyr_433, retro_tsyr_521, retro_tsyr_589, retro_tsyr_601, retro_tsyr_651, retro_tsyr_724, retro_tsyr_779, retro_tsyr_877, retro_tsyr_930, retro_tsyr_953, retro_tsyr_992,
Tursiops truncatus	ENSTTRG00000009074	16 retrocopies	retro_ttru_1241, retro_ttru_1546, retro_ttru_1690, retro_ttru_174, retro_ttru_1776, retro_ttru_1918, retro_ttru_210, retro_ttru_290, retro_ttru_367, retro_ttru_402, retro_ttru_534, retro_ttru_604, retro_ttru_726, retro_ttru_852, retro_ttru_933, retro_ttru_952,