RetrogeneDB ID: retro_lcha_63

Retrocopy location

• Organism: Coelacanth (Latimeria chalumnae)
• Coordinates: JH127084.1:296119..296701(-)
• Located in intron of: ENSLACG00000007547

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RPL7
• Ensembl ID: ENSLACG00000003571
• Aliases: None
• Description: None

Sequence

>retro_lcha_63
GAAAAGAGGAATCGCAAACAAATGAGAAAGTTGATCTTCAAGAGGGCAGAACATTACCACAAGGAATACAGACAGATGTA
CAGACGTGAGATTTGCTTAGCCAGAATGGCACGCAAAGCTGGCAACTACTATGTTCCCGCTGAACCCAAACTGGCCTTTG
TGATCAGGATCAGAGGTATCAATGGTGTCAGCCCCAAGGTCCGTAAGGTTCTGCAGCTTCTTCGCCTGCATCAGATATTC
AATGGTACCTTTGTGAAACTGAACAAGGCTTTAATCAACATGTTTCGAATTGCTGAACCATATATTGCATGGGGGTACCC
CAATCTGAAGTCTGTACGTGAGTTGATCTACAAGCATGGTTTTGCCAAGATCAAGAAGCAGCGGATTGCCTTCACTGACA
ACTCCCTTGTTGGGAATAGTCTGGGAAAATATGGCATCATCTGTGTCGAGGATTTGATCCATGAAATTTACACAGTTGGC
AAGAATTTCAAGTTTGCCAATAACTTCCTGTGGCCATTCAAGCTGTCCTCTCCCCGTGGTGGAATGAAGAAGAAGACCAC
ACACTACGTGGAAGGAGGTGAT

Alignment

ORF - retro_lcha_63 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 81.96 %
• Parental protein coverage: 84.35 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  EKRDRKQRRNLIFKRAEHYHKEYRQMYRREIRLARMARKAGNYYVPAEPKLAFVIRIRGINGVSPKVRKV
          EKR.RKQ.R.LIFKRAEHYHKEYRQMYRREI.LARMARKAGNYYVPAEPKLAFVIRIRGINGVSPKVRKV
Retrocopy EKRNRKQMRKLIFKRAEHYHKEYRQMYRREICLARMARKAGNYYVPAEPKLAFVIRIRGINGVSPKVRKV

Parental  LQLLRLRQIFNGTFVKLNKASINMLRIAEPYIAWGMASLRRRRFLVYPIDFKTLVNERVTVSSNALVQKW
          LQLLRL.QIFNGTFVKLNKA.INM.RIAEPYIAWG...L...R.L.Y...F......R.....N.LV...
Retrocopy LQLLRLHQIFNGTFVKLNKALINMFRIAEPYIAWGYPNLKSVRELIYKHGFAKIKKQRIAFTDNSLVGNS

Parental  TEKYGIICVEDLIHEIYTVGKNFKFANNFLWPFKLSSPRGGMKKKTTHYVEGGD
          ..KYGIICVEDLIHEIYTVGKNFKFANNFLWPFKLSSPRGGMKKKTTHYVEGGD
Retrocopy LGKYGIICVEDLIHEIYTVGKNFKFANNFLWPFKLSSPRGGMKKKTTHYVEGGD

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
DRP000627_gill	499.90 RPM	567.67 RPM
DRP000627_kidney	628.98 RPM	481.03 RPM
DRP000627_pectoral_fin	715.89 RPM	713.54 RPM
DRP000627_pelvic_fin	798.54 RPM	906.21 RPM
DRP000627_pharynx	416.92 RPM	460.24 RPM
DRP000627_tail_muscle	261.33 RPM	329.71 RPM

ChIP-Seq

Latimeria chalumnae was not studied using ChIP-Seq data.

EST

Latimeria chalumnae was not studied using EST data.

TSS

Latimeria chalumnae was not studied using FANTOM5 data.

Lab

retro_lcha_63 was not experimentally validated.

Homology

Retrocopy orthology:

Latimeria chalumnae does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 32 parental genes, and 422 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000001821	5 retrocopies	retro_amel_1230, retro_amel_1632, retro_amel_760, retro_amel_933, retro_amel_937,
Bos taurus	ENSBTAG00000020139	22 retrocopies	retro_btau_1088, retro_btau_1231, retro_btau_1367, retro_btau_1381, retro_btau_1422, retro_btau_1434, retro_btau_1468, retro_btau_1548, retro_btau_1559, retro_btau_1616, retro_btau_1627, retro_btau_1784, retro_btau_1814, retro_btau_304, retro_btau_426, retro_btau_622, retro_btau_668, retro_btau_730, retro_btau_750, retro_btau_758, retro_btau_863, retro_btau_879,
Canis familiaris	ENSCAFG00000008021	28 retrocopies	retro_cfam_1039, retro_cfam_1075, retro_cfam_1079, retro_cfam_1167, retro_cfam_1209, retro_cfam_1236, retro_cfam_1270, retro_cfam_1308, retro_cfam_1390, retro_cfam_1436, retro_cfam_1445, retro_cfam_1453, retro_cfam_1524, retro_cfam_1541, retro_cfam_1699, retro_cfam_1755, retro_cfam_1855, retro_cfam_1856, retro_cfam_2051, retro_cfam_2192, retro_cfam_338, retro_cfam_403, retro_cfam_563, retro_cfam_609, retro_cfam_737, retro_cfam_74, retro_cfam_922, retro_cfam_998,
Callithrix jacchus	ENSCJAG00000007686	1 retrocopy	retro_cjac_105,
Cavia porcellus	ENSCPOG00000004140	18 retrocopies	retro_cpor_1056, retro_cpor_1190, retro_cpor_1342, retro_cpor_1347, retro_cpor_1348, retro_cpor_1366, retro_cpor_1418, retro_cpor_1449, retro_cpor_1452, retro_cpor_1453, retro_cpor_187, retro_cpor_209, retro_cpor_245, retro_cpor_266, retro_cpor_397, retro_cpor_458, retro_cpor_506, retro_cpor_640,
Dasypus novemcinctus	ENSDNOG00000017654	15 retrocopies	retro_dnov_1561, retro_dnov_1692, retro_dnov_182, retro_dnov_1893, retro_dnov_209, retro_dnov_2158, retro_dnov_2568, retro_dnov_264, retro_dnov_2657, retro_dnov_279, retro_dnov_287, retro_dnov_365, retro_dnov_655, retro_dnov_77, retro_dnov_971,
Equus caballus	ENSECAG00000009188	1 retrocopy	retro_ecab_35,
Erinaceus europaeus	ENSEEUG00000010307	3 retrocopies	retro_eeur_354, retro_eeur_420, retro_eeur_55,
Echinops telfairi	ENSETEG00000005656	33 retrocopies	retro_etel_1099, retro_etel_1120, retro_etel_1154, retro_etel_1158, retro_etel_1333, retro_etel_1370, retro_etel_1553, retro_etel_1642, retro_etel_1708, retro_etel_1720, retro_etel_175, retro_etel_185, retro_etel_1891, retro_etel_2042, retro_etel_2044, retro_etel_2118, retro_etel_2149, retro_etel_265, retro_etel_316, retro_etel_375, retro_etel_402, retro_etel_519, retro_etel_532, retro_etel_554, retro_etel_610, retro_etel_793, retro_etel_865, retro_etel_869, retro_etel_877, retro_etel_887, retro_etel_889, retro_etel_992, retro_etel_993,
Felis catus	ENSFCAG00000028446	6 retrocopies	retro_fcat_1643, retro_fcat_230, retro_fcat_255, retro_fcat_338, retro_fcat_342, retro_fcat_945,
Homo sapiens	ENSG00000147604	49 retrocopies	retro_hsap_1001, retro_hsap_1023, retro_hsap_1033, retro_hsap_1034, retro_hsap_1128, retro_hsap_113, retro_hsap_1232, retro_hsap_1281, retro_hsap_1614, retro_hsap_1626, retro_hsap_1844, retro_hsap_1862, retro_hsap_1957, retro_hsap_2008, retro_hsap_203, retro_hsap_2093, retro_hsap_2101, retro_hsap_2588, retro_hsap_2837, retro_hsap_3197, retro_hsap_3204, retro_hsap_3244, retro_hsap_3254, retro_hsap_3356, retro_hsap_3399, retro_hsap_344, retro_hsap_3453, retro_hsap_3493, retro_hsap_3560, retro_hsap_3573, retro_hsap_3625, retro_hsap_3717, retro_hsap_3775, retro_hsap_3883, retro_hsap_3918, retro_hsap_4137, retro_hsap_415, retro_hsap_426, retro_hsap_4306, retro_hsap_4662, retro_hsap_4704, retro_hsap_4718, retro_hsap_4761, retro_hsap_558, retro_hsap_616, retro_hsap_708, retro_hsap_729, retro_hsap_973, retro_hsap_976,
Latimeria chalumnae	ENSLACG00000003571	1 retrocopy	retro_lcha_63 ,
Loxodonta africana	ENSLAFG00000017110	10 retrocopies	retro_lafr_140, retro_lafr_169, retro_lafr_334, retro_lafr_462, retro_lafr_47, retro_lafr_524, retro_lafr_694, retro_lafr_707, retro_lafr_816, retro_lafr_909,
Macropus eugenii	ENSMEUG00000016319	9 retrocopies	retro_meug_1002, retro_meug_1449, retro_meug_1942, retro_meug_1947, retro_meug_60, retro_meug_760, retro_meug_84, retro_meug_968, retro_meug_99,
Microcebus murinus	ENSMICG00000002880	8 retrocopies	retro_mmur_1170, retro_mmur_1379, retro_mmur_139, retro_mmur_158, retro_mmur_52, retro_mmur_596, retro_mmur_646, retro_mmur_903,
Myotis lucifugus	ENSMLUG00000028550	3 retrocopies	retro_mluc_1478, retro_mluc_2000, retro_mluc_640,
Macaca mulatta	ENSMMUG00000005141	1 retrocopy	retro_mmul_129,
Monodelphis domestica	ENSMODG00000007136	4 retrocopies	retro_mdom_1341, retro_mdom_1998, retro_mdom_371, retro_mdom_66,
Mustela putorius furo	ENSMPUG00000010240	15 retrocopies	retro_mputfur_1004, retro_mputfur_1031, retro_mputfur_1034, retro_mputfur_1035, retro_mputfur_1156, retro_mputfur_1168, retro_mputfur_1384, retro_mputfur_1454, retro_mputfur_1481, retro_mputfur_390, retro_mputfur_410, retro_mputfur_545, retro_mputfur_839, retro_mputfur_929, retro_mputfur_982,
Mus musculus	ENSMUSG00000043716	15 retrocopies	retro_mmus_1232, retro_mmus_1345, retro_mmus_1631, retro_mmus_2549, retro_mmus_2562, retro_mmus_2798, retro_mmus_3259, retro_mmus_3305, retro_mmus_3440, retro_mmus_3547, retro_mmus_3552, retro_mmus_3685, retro_mmus_561, retro_mmus_595, retro_mmus_708,
Nomascus leucogenys	ENSNLEG00000026615	8 retrocopies	retro_nleu_1012, retro_nleu_1459, retro_nleu_1696, retro_nleu_1853, retro_nleu_2479, retro_nleu_2603, retro_nleu_3, retro_nleu_901,
Oryctolagus cuniculus	ENSOCUG00000008407	12 retrocopies	retro_ocun_109, retro_ocun_1164, retro_ocun_1282, retro_ocun_1342, retro_ocun_1494, retro_ocun_1646, retro_ocun_1879, retro_ocun_456, retro_ocun_501, retro_ocun_718, retro_ocun_727, retro_ocun_785,
Otolemur garnettii	ENSOGAG00000003903	2 retrocopies	retro_ogar_15, retro_ogar_225,
Pongo abelii	ENSPPYG00000018671	50 retrocopies	retro_pabe_1025, retro_pabe_1061, retro_pabe_1087, retro_pabe_1326, retro_pabe_1454, retro_pabe_1520, retro_pabe_1642, retro_pabe_1677, retro_pabe_1908, retro_pabe_1998, retro_pabe_2004, retro_pabe_2118, retro_pabe_2197, retro_pabe_2348, retro_pabe_2656, retro_pabe_2690, retro_pabe_2762, retro_pabe_2796, retro_pabe_2807, retro_pabe_2808, retro_pabe_2856, retro_pabe_2886, retro_pabe_2936, retro_pabe_2946, retro_pabe_307, retro_pabe_3085, retro_pabe_3117, retro_pabe_3139, retro_pabe_3191, retro_pabe_3414, retro_pabe_3468, retro_pabe_3506, retro_pabe_352, retro_pabe_3622, retro_pabe_3651, retro_pabe_3662, retro_pabe_3669, retro_pabe_3675, retro_pabe_436, retro_pabe_497, retro_pabe_514, retro_pabe_551, retro_pabe_628, retro_pabe_655, retro_pabe_826, retro_pabe_844, retro_pabe_859, retro_pabe_865, retro_pabe_867, retro_pabe_933,
Pteropus vampyrus	ENSPVAG00000009292	10 retrocopies	retro_pvam_105, retro_pvam_109, retro_pvam_1192, retro_pvam_1221, retro_pvam_151, retro_pvam_287, retro_pvam_308, retro_pvam_68, retro_pvam_69, retro_pvam_995,
Rattus norvegicus	ENSRNOG00000006992	27 retrocopies	retro_rnor_1018, retro_rnor_1174, retro_rnor_1222, retro_rnor_1233, retro_rnor_1307, retro_rnor_1388, retro_rnor_1466, retro_rnor_1580, retro_rnor_1745, retro_rnor_1916, retro_rnor_1944, retro_rnor_2025, retro_rnor_2028, retro_rnor_2100, retro_rnor_2247, retro_rnor_2304, retro_rnor_2347, retro_rnor_2531, retro_rnor_2715, retro_rnor_2765, retro_rnor_2814, retro_rnor_2824, retro_rnor_530, retro_rnor_666, retro_rnor_911, retro_rnor_929, retro_rnor_977,
Sorex araneus	ENSSARG00000001088	3 retrocopies	retro_sara_268, retro_sara_310, retro_sara_623,
Sus scrofa	ENSSSCG00000006182	3 retrocopies	retro_sscr_1138, retro_sscr_209, retro_sscr_796,
Ictidomys tridecemlineatus	ENSSTOG00000004586	18 retrocopies	retro_itri_1025, retro_itri_1080, retro_itri_1358, retro_itri_1375, retro_itri_1412, retro_itri_1430, retro_itri_1464, retro_itri_1593, retro_itri_1776, retro_itri_271, retro_itri_346, retro_itri_349, retro_itri_351, retro_itri_390, retro_itri_534, retro_itri_542, retro_itri_827, retro_itri_917,
Tupaia belangeri	ENSTBEG00000002301	1 retrocopy	retro_tbel_2042,
Tarsius syrichta	ENSTSYG00000006100	25 retrocopies	retro_tsyr_1149, retro_tsyr_1200, retro_tsyr_1293, retro_tsyr_1297, retro_tsyr_1403, retro_tsyr_1598, retro_tsyr_1633, retro_tsyr_1850, retro_tsyr_1891, retro_tsyr_191, retro_tsyr_2109, retro_tsyr_2130, retro_tsyr_344, retro_tsyr_421, retro_tsyr_433, retro_tsyr_521, retro_tsyr_589, retro_tsyr_601, retro_tsyr_651, retro_tsyr_724, retro_tsyr_779, retro_tsyr_877, retro_tsyr_930, retro_tsyr_953, retro_tsyr_992,
Tursiops truncatus	ENSTTRG00000009074	16 retrocopies	retro_ttru_1241, retro_ttru_1546, retro_ttru_1690, retro_ttru_174, retro_ttru_1776, retro_ttru_1918, retro_ttru_210, retro_ttru_290, retro_ttru_367, retro_ttru_402, retro_ttru_534, retro_ttru_604, retro_ttru_726, retro_ttru_852, retro_ttru_933, retro_ttru_952,