RetrogeneDB ID: retro_chof_1701

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_36217:1..526(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: CDV3
• Ensembl ID: ENSCHOG00000008963
• Aliases: None
• Description: CDV3 homolog (mouse) [Source:HGNC Symbol;Acc:26928]

Sequence

>retro_chof_1701
GATGAAGATGGATGGAAAGAATTCGAGCAAAAAGAGGTTGATTGCAGCAGCCTCCAAGTTCAGGCAATGTAAATAAGTGA
AAAGGAAAAAGATGATAACGAAAAGAGAGAAGATTCAGCTGATAACTGGGAAGAAGGTGGAGGTGGTGGTGGTATAGAAA
AATCTTCAGGTCACTGGTCCTGGTACTCTGATACAAGCACCTCCTATTCCAGTAATTGTTAAAGAAATCCCAGAACTGGT
GATGACTAGTGGTTTGTATAGGTCTTCTGGGGCCAAGTTAACCACAACAAGGAAAACACAGCAAGGACCACCAGAAATAT
ACAGTGATACACAGTTCCCATCCCTGCAGTTTACTGCCAAGCATGTAGAAAGCTGGAAGGATAAAGAAATGGAGAAGAAT
TTGAAGTAGTAAGACACAGAAATGGAGGTAGGGATTAGATTTCAAAAAACCAGGCCCTTAAACTTCAGCTAGACAACCAT
TATTCTGTGCTTGAAAATCAGAAAAGCAGCCACACACAGTACAAT

Alignment

ORF - retro_chof_1701 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 76.11 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  DEDEWKEFEQKEVDYSGLRVQAMQISSEKEEDDNEKREDPGDNWEEGGGGGGG-VEKSSGPWNKTALVQA
          DED.WKEFEQKEVD.S.L.VQAM.IS.EKE.DDNEKRED..DNWEEGG..GGG.V.K.........L.QA
Retrocopy DEDGWKEFEQKEVDCSSLQVQAM*IS-EKEKDDNEKREDSADNWEEGG--GGG>V*KNLQVTGPGTLIQA

Parental  PPAPVIVTETPEPVMTSGVYRPPGARLTTTRKTPQGPPEIYSDTQFPSLQSTAKHVESRKDKEMEKS-FE
          PP.PVIV.E.PE.VMTSG.YR..GA.LTTTRKT.QGPPEIYSDTQFPSLQ.TAKHVES.KDKEMEK..FE
Retrocopy PPIPVIVKEIPELVMTSGLYRSSGAKLTTTRKTQQGPPEIYSDTQFPSLQFTAKHVESWKDKEMEKN<FE

Parental  VVRHKNRGRDEVSKNQALKLQLDNQYAVLENQKSSLTQYN
          VVRH.N.GRD..SKNQALKLQLDN.Y.VLENQKSS.TQYN
Retrocopy VVRHRNGGRD*ISKNQALKLQLDNHYSVLENQKSSHTQYN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_1701 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 17 parental genes, and 42 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000035556	1 retrocopy	retro_btau_253,
Choloepus hoffmanni	ENSCHOG00000008963	5 retrocopies	retro_chof_1355, retro_chof_1701 , retro_chof_1763, retro_chof_2308, retro_chof_818,
Callithrix jacchus	ENSCJAG00000002998	1 retrocopy	retro_cjac_2928,
Dasypus novemcinctus	ENSDNOG00000010208	5 retrocopies	retro_dnov_2359, retro_dnov_2616, retro_dnov_460, retro_dnov_496, retro_dnov_656,
Equus caballus	ENSECAG00000015689	2 retrocopies	retro_ecab_444, retro_ecab_636,
Homo sapiens	ENSG00000091527	1 retrocopy	retro_hsap_2678,
Gorilla gorilla	ENSGGOG00000027821	1 retrocopy	retro_ggor_1869,
Myotis lucifugus	ENSMLUG00000009864	1 retrocopy	retro_mluc_1296,
Mus musculus	ENSMUSG00000032803	10 retrocopies	retro_mmus_1266, retro_mmus_2405, retro_mmus_2408, retro_mmus_2411, retro_mmus_2412, retro_mmus_2416, retro_mmus_2418, retro_mmus_2422, retro_mmus_2423, retro_mmus_2534,
Nomascus leucogenys	ENSNLEG00000003470	1 retrocopy	retro_nleu_1181,
Oryctolagus cuniculus	ENSOCUG00000012748	1 retrocopy	retro_ocun_1106,
Ochotona princeps	ENSOPRG00000003600	3 retrocopies	retro_opri_1017, retro_opri_739, retro_opri_740,
Pongo abelii	ENSPPYG00000025898	1 retrocopy	retro_pabe_2301,
Pan troglodytes	ENSPTRG00000015409	1 retrocopy	retro_ptro_1805,
Sus scrofa	ENSSSCG00000011637	1 retrocopy	retro_sscr_701,
Tupaia belangeri	ENSTBEG00000014910	5 retrocopies	retro_tbel_2284, retro_tbel_2443, retro_tbel_4022, retro_tbel_4157, retro_tbel_4378,
Tarsius syrichta	ENSTSYG00000011401	2 retrocopies	retro_tsyr_1381, retro_tsyr_1759,