RetrogeneDB ID: retro_ggor_2965

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: X:132221976..132222553(+)
• Located in intron of: ENSGGOG00000013253

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RPS7
• Ensembl ID: ENSGGOG00000023095
• Aliases: None
• Description: None

Sequence

>retro_ggor_2965
TTCAGTTTGAACACTAGGATCACGAAGCCCAACGGCAAGAAGCCAGACAAGTTCAAGTTCGGCATCTCCCAGGCTCTTCT
GGAGCCAAAGATGAACGTGGACCTCAAGGCTCGGCTCAGGGAGCTGAATATCACAGCAGCCAAGGAAACTGAAGTTGGTG
GTAGTCAGAAAGCTATCATAATCTTTGTTCCTGTTTCTCGACTGAAATCTTCCCAGAAAATCCAAGTCTGGCTAGTACGT
GAATTGGAGAAAAAGTTCAGTGAGAAGCATGTTGTCTTTATTGCTCAGAGGAGAATCCTGCCTAAGCCAACTTGAAAAAG
CCATACAAAAAATAAGCAAAAGCATCACAGGAGCTGTACTCTGATAGCTGCGTACCATGCGATCTTGAGGACTTGGTCTT
TCCAAGTGAAATTGTGGGCAAGAGAATCCACTTGAAACTGGATGGCAGCTGCCTCGCAAAAGTTCATTTGGACAAAGCAC
AGCAGAACAATGTGGCACACAAGGTTGAAACTTTTCTGGTGTCTTTAAGAAGCTCATAGGTAACGATGTTAATTTTGAAT
TCCCAGAGTTTCACTTG

Alignment

ORF - retro_ggor_2965 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 78.97 %
• Parental protein coverage: 99.48 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  FSSSAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKS
          FS....I.KPNG.KPD.F..GISQALLE..MN.DLKA.LRELNITAAKE.EVGG..KAIIIFVPV..LKS
Retrocopy FSLNTRITKPNGKKPDKFKFGISQALLEPKMNVDLKARLRELNITAAKETEVGGSQKAIIIFVPVSRLKS

Parental  FQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAI-LEDLVFPSEIV
          .QKIQV.LVRELEKKFS.KHVVFIAQRRILPKPT.KS.TKNKQK..RS.TL.A...AI.LEDLVFPSEIV
Retrocopy SQKIQVWLVRELEKKFSEKHVVFIAQRRILPKPT*KSHTKNKQKHHRSCTLIAAYHAI<LEDLVFPSEIV

Parental  GKRIRVKLDGSRLIKVHLDKAQQNNVEHKVET-FSGVYKKLTGKDVNFEFPEFQL
          GKRI..KLDGS.L.KVHLDKAQQNNV.HKVET.FSGV.KKL.G.DVNFEFPEF.L
Retrocopy GKRIHLKLDGSCLAKVHLDKAQQNNVAHKVET<FSGVFKKLIGNDVNFEFPEFHL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	49.73 RPM
SRP007412_cerebellum	0.00 RPM	84.31 RPM
SRP007412_heart	0.00 RPM	35.52 RPM
SRP007412_kidney	0.00 RPM	189.03 RPM
SRP007412_liver	0.00 RPM	183.46 RPM
SRP007412_testis	0.00 RPM	82.36 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2965 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2965 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_4760
Macaca mulatta	retro_mmul_2540

---

Parental genes homology:

Parental genes homology involve 19 parental genes, and 99 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000018435	2 retrocopies	retro_amel_391, retro_amel_914,
Bos taurus	ENSBTAG00000016224	5 retrocopies	retro_btau_1016, retro_btau_1046, retro_btau_1351, retro_btau_448, retro_btau_997,
Canis familiaris	ENSCAFG00000003263	1 retrocopy	retro_cfam_1798,
Cavia porcellus	ENSCPOG00000009795	2 retrocopies	retro_cpor_1139, retro_cpor_773,
Dasypus novemcinctus	ENSDNOG00000013285	14 retrocopies	retro_dnov_1091, retro_dnov_1351, retro_dnov_1388, retro_dnov_1459, retro_dnov_1688, retro_dnov_1849, retro_dnov_1940, retro_dnov_1970, retro_dnov_238, retro_dnov_2409, retro_dnov_558, retro_dnov_582, retro_dnov_623, retro_dnov_791,
Equus caballus	ENSECAG00000020253	2 retrocopies	retro_ecab_276, retro_ecab_396,
Felis catus	ENSFCAG00000023243	2 retrocopies	retro_fcat_1534, retro_fcat_41,
Gorilla gorilla	ENSGGOG00000023095	13 retrocopies	retro_ggor_2028, retro_ggor_2090, retro_ggor_2161, retro_ggor_218, retro_ggor_2452, retro_ggor_2927, retro_ggor_294, retro_ggor_2965 , retro_ggor_3047, retro_ggor_346, retro_ggor_400, retro_ggor_484, retro_ggor_597,
Macaca mulatta	ENSMMUG00000011870	7 retrocopies	retro_mmul_1831, retro_mmul_1846, retro_mmul_1929, retro_mmul_23, retro_mmul_2403, retro_mmul_2540, retro_mmul_357,
Monodelphis domestica	ENSMODG00000014495	2 retrocopies	retro_mdom_662, retro_mdom_810,
Mus musculus	ENSMUSG00000061477	2 retrocopies	retro_mmus_271, retro_mmus_53,
Nomascus leucogenys	ENSNLEG00000015407	10 retrocopies	retro_nleu_1505, retro_nleu_1771, retro_nleu_1783, retro_nleu_2278, retro_nleu_2346, retro_nleu_2510, retro_nleu_2892, retro_nleu_3080, retro_nleu_817, retro_nleu_835,
Oryctolagus cuniculus	ENSOCUG00000008507	2 retrocopies	retro_ocun_203, retro_ocun_230,
Pongo abelii	ENSPPYG00000025872	12 retrocopies	retro_pabe_1033, retro_pabe_1555, retro_pabe_2506, retro_pabe_2982, retro_pabe_2983, retro_pabe_31, retro_pabe_313, retro_pabe_360, retro_pabe_3659, retro_pabe_3803, retro_pabe_499, retro_pabe_524,
Pteropus vampyrus	ENSPVAG00000002071	7 retrocopies	retro_pvam_1051, retro_pvam_1183, retro_pvam_1330, retro_pvam_1437, retro_pvam_207, retro_pvam_543, retro_pvam_887,
Rattus norvegicus	ENSRNOG00000008551	2 retrocopies	retro_rnor_39, retro_rnor_391,
Sus scrofa	ENSSSCG00000027353	5 retrocopies	retro_sscr_136, retro_sscr_137, retro_sscr_240, retro_sscr_364, retro_sscr_956,
Ictidomys tridecemlineatus	ENSSTOG00000024830	3 retrocopies	retro_itri_1147, retro_itri_1161, retro_itri_1215,
Tursiops truncatus	ENSTTRG00000001616	6 retrocopies	retro_ttru_1422, retro_ttru_1659, retro_ttru_1706, retro_ttru_301, retro_ttru_323, retro_ttru_773,