RetrogeneDB ID: retro_ogar_2870

Retrocopy location

• Organism: Bushbaby (Otolemur garnettii)
• Coordinates: GL873674.1:2624271..2625105(+)
• Located in intron of: ENSOGAG00000015475

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: VDAC3
• Ensembl ID: ENSOGAG00000016163
• Aliases: None
• Description: voltage-dependent anion channel 3 [Source:HGNC Symbol;Acc:12674]

Sequence

>retro_ogar_2870
ATGACTGTGTCTCCCAGGTATGCTGATCTCAGCAAGTCTGCCAGGGATTTCTTCCCCTAAGGGCTACAGATTTGGCTTAA
TAAATTGATTTGAAAACAAAATCTGAGAATGGATTGGAATTTACAAGCTCAGGCTCAGCCAATACTGAGACCACCAAAGT
GACAGGCAGTCTGGAAACCAAGTACAGATGGACCCAATATGGCTTTAATGTTTATGGAGAAATGGAACACCCACAACATG
CTGGGCACCAAGATTACCGTGGAAGATCAGCTTGCCTGTGGACTGAAGCTGACCTTCAGTTCATTCTTCTCAGCTAACCC
TGGGGGAAAAATGCTAAAATCAAGATAGGGTACAAGCGAGAGCACATCAACCTGGGCTGCGACGTGGACTTTGACATTGC
TAGGCCTTCGATCGTGGTGCTCTGGTTCTGGGTTATGAGGGCTGGCTGACTGGCGGGCTACTAGATGAATTTTGGAACTG
CAAAGTCCCAAGTGACCGAGAGCAACCTTGCAGTTGGCTACAAGATGGATGAATTCCAGCTTCACACTAATGTGAATGAC
AGGACAGAGTTTGGTGGCTCCATCTACCAGAAAGTGAACAAGAAGTTGGAGACCGCTGTCAGTCTCTCCTGGACAGCAGG
AAACAGTAACACTGACTTTGGAATAGCTACCAAGTACCAAATTGACCCTGATGCCTGCTTCTTGGCTAAAGTGAACAGCT
CCAGCCTGATAAGGTTTAGGATACATTCAGACCTTAAAGCCGGGTATCAAACTGACAGTGTCAGCTCTGCTGGATGGTAA
GAATGTCAATGCCGGTGGCCACAAGACTGGAATT

Alignment

ORF - retro_ogar_2870 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 55.67 %
• Parental protein coverage: 97.88 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  MCNTPTYCDLGKAAKDVFNKGYGFGMVK-IDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKICNYG-
          M...P.Y.DL.K.A.D.F..G......K.IDLKTKS..G.EF..SG.A.T.T.K..G.LETKY....YG.
Retrocopy MTVSPRYADLSKSARDFFP*GLQIWLNK<IDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTQYG>

Parental  LTFTQKWNTDNTLGTEISLENKLAEGLKLTLDTIFVPNTGKK-SGKLKASYKRDCFSLGSNVDIDFSGPT
          L.F..KWNT.N.LGT.I..E..LA.GLKLT....F..N.G.K...K.K..YKR....LG..VD.D...P.
Retrocopy LMFMEKWNTHNMLGTKITVEDQLACGLKLTFSSFFSANPGGK<NAKIKIGYKREHINLGCDVDFDIARPS

Parental  IYG-WAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNEKIETSI
          I...W......G.LAGY.M.F.TAKS.....N.A.GYK...FQLHT.VND.TEFGGSIYQKVN.K.ET..
Retrocopy IVVLWFWVMRAG*LAGY*MNFGTAKSQVTESNLAVGYKMDEFQLHTNVNDRTEFGGSIYQKVNKKLETAV

Parental  NLAWTAGSNNTRFGIAAKYKLDCRTSLSAKVNNASLI-GLGYTQTLRPGVKLTLSALIDGKNFNAGGHKV
          .L.WTAG..NT.FGIA.KY..D......AKVN..SLI.GLGY.QTL.PG.KLT.SAL.DGKN.NAGGHK.
Retrocopy SLSWTAGNSNTDFGIATKYQIDPDACFLAKVNSSSLI>GLGYIQTLKPGIKLTVSALLDGKNVNAGGHKT

Parental  GL
          G.
Retrocopy GI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Otolemur garnettii was not studied using RNA-Seq expression data.

ChIP-Seq

Otolemur garnettii was not studied using ChIP-Seq data.

EST

Otolemur garnettii was not studied using EST data.

TSS

Otolemur garnettii was not studied using FANTOM5 data.

Lab

retro_ogar_2870 was not experimentally validated.

Homology

Retrocopy orthology:

Otolemur garnettii does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 24 parental genes, and 54 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000005095	1 retrocopy	retro_amel_729,
Bos taurus	ENSBTAG00000014068	4 retrocopies	retro_btau_1537, retro_btau_1607, retro_btau_365, retro_btau_685,
Canis familiaris	ENSCAFG00000005502	5 retrocopies	retro_cfam_1513, retro_cfam_2146, retro_cfam_258, retro_cfam_665, retro_cfam_713,
Choloepus hoffmanni	ENSCHOG00000007369	1 retrocopy	retro_chof_16,
Dasypus novemcinctus	ENSDNOG00000013885	1 retrocopy	retro_dnov_1753,
Equus caballus	ENSECAG00000000438	1 retrocopy	retro_ecab_799,
Felis catus	ENSFCAG00000010075	2 retrocopies	retro_fcat_1985, retro_fcat_599,
Homo sapiens	ENSG00000078668	1 retrocopy	retro_hsap_1375,
Gallus gallus	ENSGALG00000003755	1 retrocopy	retro_ggal_11,
Gorilla gorilla	ENSGGOG00000001932	2 retrocopies	retro_ggor_1071, retro_ggor_3043,
Microcebus murinus	ENSMICG00000010235	1 retrocopy	retro_mmur_1361,
Monodelphis domestica	ENSMODG00000015526	5 retrocopies	retro_mdom_1130, retro_mdom_1331, retro_mdom_1869, retro_mdom_420, retro_mdom_669,
Mus musculus	ENSMUSG00000008892	2 retrocopies	retro_mmus_110, retro_mmus_1505,
Nomascus leucogenys	ENSNLEG00000012890	1 retrocopy	retro_nleu_2593,
Otolemur garnettii	ENSOGAG00000016163	4 retrocopies	retro_ogar_2770, retro_ogar_2870 , retro_ogar_589, retro_ogar_995,
Otolemur garnettii	ENSOGAG00000030039	1 retrocopy	retro_ogar_2116,
Otolemur garnettii	ENSOGAG00000030742	2 retrocopies	retro_ogar_1197, retro_ogar_2876,
Pongo abelii	ENSPPYG00000018554	8 retrocopies	retro_pabe_1145, retro_pabe_1960, retro_pabe_2304, retro_pabe_3163, retro_pabe_3665, retro_pabe_3791, retro_pabe_819, retro_pabe_971,
Pan troglodytes	ENSPTRG00000020205	2 retrocopies	retro_ptro_2548, retro_ptro_945,
Pteropus vampyrus	ENSPVAG00000014822	2 retrocopies	retro_pvam_637, retro_pvam_907,
Rattus norvegicus	ENSRNOG00000019277	1 retrocopy	retro_rnor_1596,
Sarcophilus harrisii	ENSSHAG00000017953	1 retrocopy	retro_shar_658,
Tupaia belangeri	ENSTBEG00000007420	4 retrocopies	retro_tbel_1801, retro_tbel_2150, retro_tbel_2261, retro_tbel_884,
Tarsius syrichta	ENSTSYG00000007112	1 retrocopy	retro_tsyr_918,