RetrogeneDB ID: retro_ptro_2605

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 7:23203663..23203931(-)
• Located in intron of: ENSPTRG00000018993

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: SUMO2
• Ensembl ID: ENSPTRG00000042199
• Aliases: None
• Description: None

Sequence

>retro_ptro_2605
ATGGCTGACAAAAAGCCCAAGAAAGGAGTCAAGACCCAAAAAAATAACCATATAGAGTTGCAGTGGTGGGCTGGAATGGT
TCAGTGGTACAGCTCCAGAGTATATCACTTAGCAAACTAATGAGAGCCTATTGTTAACAACTGATCTATCAATGAGGCAA
CTTGGTTTTGGATGTGATGGGAGGCCAATTAATGAAACACCTGTACAGGTGAAAATGGAAGATGAAGATATAATTAATGT
GTATACAAAGCAGACAGGAAGTATCTAC

Alignment

ORF - retro_ptro_2605 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 56.7 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MADEKPKEGVKTENNDHINLK-VAGQDGSVVQFKIKRHTPLSKLMKAYCER-QGLSMRQIRFRFDGQPIN
          MAD.KPK.GVKT..N.HI.L..V.G..GSVVQ........LSKLM.AYC.....LSMRQ..F..DG.PIN
Retrocopy MADKKPKKGVKTQKNNHIELQ<VVGWNGSVVQLQ---SISLSKLMRAYC*Q<TDLSMRQLGFGCDGRPIN

Parental  ETDTPAQLEMEDEDTIDVFQQQTGGVY
          E..TP.Q..MEDED.I.V...QTG..Y
Retrocopy E--TPVQVKMEDEDIINVYTKQTGSIY

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.02 RPM	61.99 RPM
SRP007412_cerebellum	0.04 RPM	44.74 RPM
SRP007412_heart	0.00 RPM	24.83 RPM
SRP007412_kidney	0.00 RPM	32.40 RPM
SRP007412_liver	0.03 RPM	24.75 RPM
SRP007412_testis	0.11 RPM	73.98 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_2605 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_2605 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_2605 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Gorilla gorilla	retro_ggor_2576

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Parental genes homology:

Parental genes homology involve 10 parental genes, and 87 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000009189	13 retrocopies	retro_amel_1097, retro_amel_1125, retro_amel_1199, retro_amel_1263, retro_amel_1434, retro_amel_152, retro_amel_1665, retro_amel_276, retro_amel_35, retro_amel_616, retro_amel_653, retro_amel_662, retro_amel_722,
Cavia porcellus	ENSCPOG00000004581	9 retrocopies	retro_cpor_1029, retro_cpor_1297, retro_cpor_1496, retro_cpor_202, retro_cpor_357, retro_cpor_823, retro_cpor_838, retro_cpor_869, retro_cpor_894,
Homo sapiens	ENSG00000188612	2 retrocopies	retro_hsap_4036, retro_hsap_4095,
Loxodonta africana	ENSLAFG00000025811	10 retrocopies	retro_lafr_104, retro_lafr_1222, retro_lafr_1240, retro_lafr_200, retro_lafr_254, retro_lafr_324, retro_lafr_36, retro_lafr_488, retro_lafr_858, retro_lafr_888,
Monodelphis domestica	ENSMODG00000007222	11 retrocopies	retro_mdom_1263, retro_mdom_1472, retro_mdom_1474, retro_mdom_1560, retro_mdom_1598, retro_mdom_1755, retro_mdom_237, retro_mdom_378, retro_mdom_517, retro_mdom_788, retro_mdom_986,
Oryctolagus cuniculus	ENSOCUG00000028195	5 retrocopies	retro_ocun_110, retro_ocun_136, retro_ocun_175, retro_ocun_22, retro_ocun_46,
Pongo abelii	ENSPPYG00000029777	2 retrocopies	retro_pabe_164, retro_pabe_84,
Pan troglodytes	ENSPTRG00000012817	1 retrocopy	retro_ptro_119,
Pan troglodytes	ENSPTRG00000042199	19 retrocopies	retro_ptro_1004, retro_ptro_1183, retro_ptro_1263, retro_ptro_135, retro_ptro_143, retro_ptro_1775, retro_ptro_2051, retro_ptro_2147, retro_ptro_2212, retro_ptro_2247, retro_ptro_2252, retro_ptro_2400, retro_ptro_2463, retro_ptro_2528, retro_ptro_2605 , retro_ptro_2666, retro_ptro_2759, retro_ptro_3260, retro_ptro_65,
Sus scrofa	ENSSSCG00000017212	15 retrocopies	retro_sscr_1112, retro_sscr_1132, retro_sscr_1147, retro_sscr_1148, retro_sscr_123, retro_sscr_249, retro_sscr_277, retro_sscr_409, retro_sscr_591, retro_sscr_684, retro_sscr_754, retro_sscr_765, retro_sscr_814, retro_sscr_847, retro_sscr_969,