RetrogeneDB ID:

retro_ptro_3259

Retrocopy
location
Organism:Chimpanzee (Pan troglodytes)
Coordinates:X:115357772..115359011(-)
Located in intron of:ENSPTRG00000022199
Retrocopy
information
Ensembl ID:None
Aliases:None
Status:NOVEL
Parental gene
information
Parental gene summary:
Parental gene symbol:HSPA8
Ensembl ID:ENSPTRG00000004404
Aliases:None
Description:heat shock 70kDa protein 8 [Source:HGNC Symbol;Acc:5241]


Retrocopy-Parental alignment summary:






>retro_ptro_3259
GCAGTTGGTATTGATCTTGACACTGCATACTCTTGTGTGGGTGTTTTCCAGCATGGAAAAGTAGAGATAATTACCAATGA
TCAGGGAAACTGAACCACTCCAAGCTATGTCACCTTTATGAACACTGAATGATTGATTGGTGATGCCGCAAAGAATCAAG
CTGCAATGAACCCCACCAACACGGTTTTTGATGCCAAACATCTGATTGGATGCAGATTTGATGATGCTGTTGTCTAGTCT
GATATGAAGCATTGGCCCTTCATGATGGTGAATGATACTGACAGGCCCAAGGTCCAAGTAGAATACAAGGGAGAGACCAA
AATCTTCTATCCAGAGGAGGTGTCCTCTATGGTCCTCACAAAGATGAAGGAAATTGCAGAAGCCTACCTTGGGAAGACTG
TTACCAATGCTGTGGTCACAGTGCCAGCTTACTTTAATAACTCTCAGCATCAGGCTACCAAAGATGCTGGAACTATTGCT
GGTCTCAATGTACTTAGAATTATCAATGAGCCAAGTGCTGCTGATATTGCTTACGGCTTAGACAAAAAGGTTGGAGCTGA
AAGAAATGTGTTTATCTTTGACCTGAGAGGTGGCACTTTTGATGTGTCAATCCTCATTATTCAGGATGGAATCTTTGAGG
TCAAATCTGGAGACATCCACTTGGGTGAAGAAGACTTTGACAACCGAATTGTCAGCCATTTTATTGCTGAGTTCAAGCAT
AAGTATAAGAAAGACATCAGTGAGAAGAAGAGAGCTATAAGACGCCTCCGTACTGCTTGTGAACACACTAAGCATACTCT
CTCTTCCAGGACCCAGGCCAGTATTGAGGTCGATTCTCTCTAAGAATGAATTGACTTCTGTACATCCATTGCCTGTGCCC
GATTTGAAGAACTGAATGCTGACCTGTTCCATGGCACCCTTGGCCCTGTATAAAAAGCCATTCGAGATGCCAAACTAGAC
AAGTCACAGATTCATGATATTGTCTCTATTGGTGGTTATACTCATATCCCCAAGATTCAGAAGCTTCTCCAAGATGTCTT
CAATAGAAAAGAACTGAATAAGAGCATCAATCTTGATGAAGCTGTTGCTTATGGTGCAGCTATCCAGGCAGCCATCCTAT
CTGGAGACAAATCTGAAAATGTTCAAGATTTGCTGCTCTTGGATGTCAATCCTCTTTCCTTTGGTATTGAACTTGCTGGT
GGAGTCATGACTGTCCTCCTGTCCTCATCAAGCATAGTA

ORF - retro_ptro_3259 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 83.37 %
Parental protein coverage: 64.89 %
Number of stop codons detected: 6
Number of frameshifts detected 0


Retrocopy - Parental Gene Alignment:

ParentalAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIG
AVGIDL.T.YSCVGVFQHGKVEII.NDQGN.TTPSYV.F..TE.LIGDAAKNQ.AMNPTNTVFDAK.LIG
RetrocopyAVGIDLDTAYSCVGVFQHGKVEIITNDQGN*TTPSYVTFMNTE*LIGDAAKNQAAMNPTNTVFDAKHLIG
ParentalRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLG-TVTNAVVT
.RFDDAVV.SDMKHWPFM.VND..RPKVQVEYKGETK.FYPEEVSSMVLTKMKEIAEAYLG.TVTNAVVT
RetrocopyCRFDDAVV*SDMKHWPFMMVNDTDRPKVQVEYKGETKIFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVT
ParentalVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDWQVGAERNVLIFDLGGGTFDVSILTIEDG
VPAYFN.SQ.QATKDAGTIAGLNVLRIINEP.AA.IAYGLD..VGAERNV.IFDL.GGTFDVSIL.I.DG
RetrocopyVPAYFNNSQHQATKDAGTIAGLNVLRIINEPSAADIAYGLDKKVGAERNVFIFDLRGGTFDVSILIIQDG
ParentalIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEID
IFEVKS..GD.HLG.EDFDNR.V.HFIAEFK.K.KKDISE.KRA.RRLRTACE..K.TLSS.TQASIE.D
RetrocopyIFEVKS--GDIHLGEEDFDNRIVSHFIAEFKHKYKKDISEKKRAIRRLRTACEHTKHTLSSRTQASIEVD
ParentalSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFN
SL.E.IDF.TSI..ARFEELNADLF.GTL.PV.KA.RDAKLDKSQIHDIV..GG.T.IPKIQKLLQD.FN
RetrocopySL*E*IDFCTSIACARFEELNADLFHGTLGPV*KAIRDAKLDKSQIHDIVSIGGYTHIPKIQKLLQDVFN
ParentalGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI
.KELNKSIN.DEAVAYGAA.QAAILSGDKSENVQDLLLLDV.PLS.GIE.AGGVMTVL.......
RetrocopyRKELNKSINLDEAVAYGAAIQAAILSGDKSENVQDLLLLDVNPLSFGIELAGGVMTVLLSSSSIV

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
SRP007412_brain_prefrontal_cortex 0 .91 RPM 845 .51 RPM
SRP007412_cerebellum 0 .22 RPM 738 .30 RPM
SRP007412_heart 0 .17 RPM 709 .86 RPM
SRP007412_kidney 0 .34 RPM 971 .90 RPM
SRP007412_liver 0 .29 RPM 502 .96 RPM
SRP007412_testis 0 .00 RPM 445 .77 RPM
Pan troglodytes was not studied using ChIP-Seq data.
No EST(s) were mapped for retro_ptro_3259 retrocopy.
Pan troglodytes was not studied using FANTOM5 data.
retro_ptro_3259 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_ptro_3259 has 4 orthologous retrocopies within eutheria group .

Species RetrogeneDB ID
Homo sapiens retro_hsap_4892
Gorilla gorilla retro_ggor_3054
Pongo abelii retro_pabe_3804
Macaca mulatta retro_mmul_2628

Parental genes homology:
Parental genes homology involve 29 parental genes, and 76 retrocopies.

Species Parental gene accession Retrocopies number
Anolis carolinensis ENSACAG000000048842 retrocopies
Ailuropoda melanoleuca ENSAMEG000000084251 retrocopy
Anas platyrhynchos ENSAPLG000000106671 retrocopy
Bos taurus ENSBTAG000000131621 retrocopy
Canis familiaris ENSCAFG000000116663 retrocopies
Ciona intestinalis ENSCING000000096651 retrocopy
Cavia porcellus ENSCPOG000000041693 retrocopies
Ciona savignyi ENSCSAVG000000085881 retrocopy
Dipodomys ordii ENSDORG000000154671 retrocopy
Echinops telfairi ENSETEG000000109961 retrocopy
Ficedula albicollis ENSFALG000000058121 retrocopy
Felis catus ENSFCAG000000011326 retrocopies
Homo sapiens ENSG000001099718 retrocopies
Gallus gallus ENSGALG000000065121 retrocopy
Loxodonta africana ENSLAFG000000303124 retrocopies
Meleagris gallopavo ENSMGAG000000019291 retrocopy
Myotis lucifugus ENSMLUG000000048343 retrocopies
Macaca mulatta ENSMMUG000000046967 retrocopies
Monodelphis domestica ENSMODG000000129582 retrocopies
Mustela putorius furoENSMPUG000000058109 retrocopies
Oreochromis niloticus ENSONIG000000047591 retrocopy
Pelodiscus sinensis ENSPSIG000000124502 retrocopies
Pan troglodytes ENSPTRG000000005631 retrocopy
Pan troglodytes ENSPTRG00000004404 5 retrocopies
Pan troglodytes ENSPTRG000000172901 retrocopy
Taeniopygia guttata ENSTGUG000000004911 retrocopy
Takifugu rubripes ENSTRUG000000052651 retrocopy
Tursiops truncatus ENSTTRG000000111396 retrocopies
Xiphophorus maculatus ENSXMAG000000016021 retrocopy



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