RetrogeneDB ID: retro_chof_396

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_103461:3387..3802(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RAB18
• Ensembl ID: ENSCHOG00000005565
• Aliases: None
• Description: RAB18, member RAS oncogene family [Source:HGNC Symbol;Acc:14244]

Sequence

>retro_chof_396
TTTAAGGTGAAAACAATTTCAGTAGATGGAAATAAAACTAAACCTGCAATATGGGATACTGCTTGTCAAGAGTGGTTCAG
AACATTAACTCCCAGCAACTTTAAAGGTGCATGGGTTTTATATTAGCTTTAATGTCACAAGAAGAGAAACCTTTCTTAAA
CTGGGTAGTTGGTTAAATGAATTGGAAACATACTGTACAAGAAATGACATAGAAAACATGCTATTTGCAAATAAAATTGA
TAAGGAAAATCATGAAGTTGATATAAATGAAGGACTGAAATTTGCATGAAAGCATTCCATGTTATTTATAGAGGCAAGAG
CAAAAACCTCTGTTGGTGTCCAATGTGCCTTTGAGGAACATGTTGAAAAGGTCATTCAGACCCCTGGACTGTGGAAAAGC
TAGAAACAGAAGGAA

Alignment

ORF - retro_chof_396 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 68.53 %
• Parental protein coverage: 57.55 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  FMLKGQIVNRPSLKWTIWKYDTAGQERFRTLTPSYYRGA-QGVILV-YDVTRRDTFLKLDNWLNELETYC
          F..K...V.....K..IW..DTA.QE.FRTLTPS...GA..G.IL....VTRR.TFLKL..WLNELETYC
Retrocopy FKVKTISVDGNKTKPAIW--DTACQEWFRTLTPSNFKGA<MGFILA<FNVTRRETFLKLGSWLNELETYC

Parental  TRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESEN
          TRNDI.NML..NKIDKEN.EVD.NEGLKFA.KHSMLFIEA.AKT..GVQCAFEE.VEK.IQTPGLW.S..
Retrocopy TRNDIENMLFANKIDKENHEVDINEGLKFA*KHSMLFIEARAKTSVGVQCAFEEHVEKVIQTPGLWKS*K

Parental  QNK
          Q..
Retrocopy QKE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_396 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

---

Parental genes homology:

Parental genes homology involve 9 parental genes, and 16 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000009871	1 retrocopy	retro_btau_1691,
Choloepus hoffmanni	ENSCHOG00000005565	4 retrocopies	retro_chof_2391, retro_chof_256, retro_chof_396 , retro_chof_846,
Cavia porcellus	ENSCPOG00000002234	2 retrocopies	retro_cpor_633, retro_cpor_652,
Dipodomys ordii	ENSDORG00000014338	1 retrocopy	retro_dord_419,
Monodelphis domestica	ENSMODG00000008253	1 retrocopy	retro_mdom_146,
Oryctolagus cuniculus	ENSOCUG00000022307	2 retrocopies	retro_ocun_1699, retro_ocun_841,
Otolemur garnettii	ENSOGAG00000028015	2 retrocopies	retro_ogar_2587, retro_ogar_2973,
Rattus norvegicus	ENSRNOG00000018972	2 retrocopies	retro_rnor_2744, retro_rnor_2962,
Sarcophilus harrisii	ENSSHAG00000007613	1 retrocopy	retro_shar_281,