RetrogeneDB ID: retro_ggor_698

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 11:18686327..18686744(-)
• Located in intron of: ENSGGOG00000010350

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: WBP2
• Ensembl ID: ENSGGOG00000009241
• Aliases: None
• Description: None

Sequence

>retro_ggor_698
ACCTTTACAGCAGGGAGCATCACTGAGTTTGGACAATGGGTGCTACGGGTGGCAGTTTAAGCCTCCAGAGGTAAGCCCCC
AGTGGAGCCTATAGATGCTCTTACATGCCCGGTGGGGCCTGTGCCTCCCATCACCAGCTGCAATGGAATGCACTCCTGCC
CTTCTGTACTCCTATCCACCACCTCCACCTGAGTTCTATCTGGGACCTCCCATCATGGATAGGGCCATGAAACAGGTGCA
GCCCCATGGCACTGCCCTATCCTGGGCCCTGGAACCTTCCATCAGAAGCCCCAAAATTCCCTCCATTCCTGCAGCCAAGG
CCGAGAAGCAGCTGCCAGAGCCTATTACAACCTGGGCAACTCACATAACATCTACATGCATAGGTACCAGCCTCCACCAC
CTCCATACTATCCTCCC

Alignment

ORF - retro_ggor_698 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 58.78 %
• Parental protein coverage: 54.79 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 5

Retrocopy - Parental Gene Alignment:

Parental  TFTAGGAIEFGQRMLQVASQASRGE-VPSGAYGYSYMPSGAYV-YPPPVANGMYPCPPGYPYPPPPPEFY
          TFTAG...EFGQ..L.VA..ASRG...PSGAY..SYMP.GA....P.P.A....P....Y.YPPPPPEFY
Retrocopy TFTAGSITEFGQWVLRVAV*ASRGK<APSGAYRCSYMPGGACA<LPSPAAMECTPALL-YSYPPPPPEFY

Parental  PGPPMMDGAMGYVQPPPP-PYPGP-MEPPVSGPDVPSTPAAEA-KAAEAAASAYYNPGNPHNVYMPTSQP
          .GPP.MD.AM..VQP....PYPGP..EP....P..PS.PAA.A...A.A.A..YYN.GN.HN.YM...QP
Retrocopy LGPPIMDRAMKQVQPHGT>PYPGP<LEPSIRSPKIPSIPAAKA<REAAARA--YYNLGNSHNIYMHRYQP

Parental  PPPPYYPP
          PPPPYYPP
Retrocopy PPPPYYPP

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.10 RPM	352.56 RPM
SRP007412_cerebellum	0.04 RPM	259.36 RPM
SRP007412_heart	0.06 RPM	77.96 RPM
SRP007412_kidney	0.08 RPM	85.38 RPM
SRP007412_liver	0.03 RPM	60.85 RPM
SRP007412_testis	0.73 RPM	141.52 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_698 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_698 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 14 parental genes, and 22 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000004946	1 retrocopy	retro_cfam_1038,
Callithrix jacchus	ENSCJAG00000037619	1 retrocopy	retro_cjac_575,
Felis catus	ENSFCAG00000005760	1 retrocopy	retro_fcat_1454,
Homo sapiens	ENSG00000132471	1 retrocopy	retro_hsap_1926,
Gorilla gorilla	ENSGGOG00000009241	2 retrocopies	retro_ggor_1404, retro_ggor_698 ,
Macropus eugenii	ENSMEUG00000000070	1 retrocopy	retro_meug_579,
Macaca mulatta	ENSMMUG00000009381	2 retrocopies	retro_mmul_1062, retro_mmul_854,
Monodelphis domestica	ENSMODG00000007725	3 retrocopies	retro_mdom_1410, retro_mdom_1847, retro_mdom_375,
Mustela putorius furo	ENSMPUG00000013775	1 retrocopy	retro_mputfur_645,
Nomascus leucogenys	ENSNLEG00000001625	1 retrocopy	retro_nleu_1214,
Ochotona princeps	ENSOPRG00000006045	2 retrocopies	retro_opri_301, retro_opri_851,
Pongo abelii	ENSPPYG00000008640	3 retrocopies	retro_pabe_693, retro_pabe_75, retro_pabe_913,
Pan troglodytes	ENSPTRG00000009660	1 retrocopy	retro_ptro_15,
Ictidomys tridecemlineatus	ENSSTOG00000021421	2 retrocopies	retro_itri_1585, retro_itri_660,