RetrogeneDB ID: retro_ggor_989

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 13:24257677..24258135(-)
• Located in intron of: ENSGGOG00000000410

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: CHCHD2
• Ensembl ID: ENSGGOG00000014938
• Aliases: None
• Description: None

Sequence

>retro_ggor_989
ATGGCACATGGAAGTCAAAGCTGCACCTCCAGCATGGCCCCTCTGGCCAGCCAGCCACCTCCAATGAGACCTGCACCCCG
GCCAGCACCAGCAGCTCAGCTGCCAGCAGTGGCCCCACCCACTGCAGTTGAGTCTCCTGCTGCTGCATCCTGGCAGCCAG
GTCTGATGGTCCAGATGGCAACCACTGCAGCTGGCGTGGCTGTGGGCCCTGCTGTGGGACATATACTGGGTCAACTATCA
TGGGAATGGGGGGGCTTAAACAGAGGAAGTAATGCTGGGCTCACAAGGCCTGACATCACTTACCAGGAGCCTCTGGGAGA
CTAGCTGCACAGCAGCAGCCACCTTGCTTGTATAAGACAGAACAGTTTCTGGAGTGTTCCCAGAACTAGGGTGATGTCAA
GCTCAGTGAGGGTTCCAATGAGATGCTGAAACAGTGCAGACGTGCACATGGACTGGCC

Alignment

ORF - retro_ggor_989 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 67.53 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MPRGSRSRTSRMAPPASRAPQMRAAPRPAPVAQPPAAAPPSAVGSSAAAPRQPGLMAQMATTAAGVAVGS
          M..GS.S.TS.MAP.AS..P.MR.APRPAP.AQ.PA.APP.AV.S.AAA..QPGLM.QMATTAAGVAVG.
Retrocopy MAHGSQSCTSSMAPLASQPPPMRPAPRPAPAAQLPAVAPPTAVESPAAASWQPGLMVQMATTAAGVAVGP

Parental  AVGHTLGHAI--TGGFSGGSNAEPARPDITYQEP-QGTQPAQQQQPCLYEIKQFLECAQNQGDIKLCEGF
          AVGH.LG......GG...GSNA...RPDITYQEP..G...AQQQ.PCLY...QFLEC.QN.GD.KL.EG.
Retrocopy AVGHILGQLSWEWGGLNRGSNAGLTRPDITYQEP<SGRLAAQQQPPCLYKTEQFLECSQN*GDVKLSEGS

Parental  NEVLKQCRLANGLA
          NE.LKQCR.A.GLA
Retrocopy NEMLKQCRRAHGLA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	58.36 RPM
SRP007412_cerebellum	0.00 RPM	48.74 RPM
SRP007412_heart	0.00 RPM	43.12 RPM
SRP007412_kidney	0.00 RPM	92.25 RPM
SRP007412_liver	0.00 RPM	49.51 RPM
SRP007412_testis	0.00 RPM	38.85 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_989 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_989 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Pan troglodytes	retro_ptro_3046

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 72 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000016050	2 retrocopies	retro_amel_500, retro_amel_976,
Bos taurus	ENSBTAG00000040295	2 retrocopies	retro_btau_397, retro_btau_768,
Canis familiaris	ENSCAFG00000010178	1 retrocopy	retro_cfam_1653,
Callithrix jacchus	ENSCJAG00000021267	1 retrocopy	retro_cjac_271,
Erinaceus europaeus	ENSEEUG00000012857	1 retrocopy	retro_eeur_398,
Echinops telfairi	ENSETEG00000008598	1 retrocopy	retro_etel_45,
Homo sapiens	ENSG00000106153	8 retrocopies	retro_hsap_116, retro_hsap_1180, retro_hsap_1995, retro_hsap_3063, retro_hsap_3186, retro_hsap_4057, retro_hsap_4184, retro_hsap_4752,
Gorilla gorilla	ENSGGOG00000014938	8 retrocopies	retro_ggor_2103, retro_ggor_220, retro_ggor_2725, retro_ggor_2807, retro_ggor_2808, retro_ggor_2958, retro_ggor_918, retro_ggor_989 ,
Myotis lucifugus	ENSMLUG00000015151	1 retrocopy	retro_mluc_345,
Mus musculus	ENSMUSG00000070493	2 retrocopies	retro_mmus_2340, retro_mmus_2536,
Nomascus leucogenys	ENSNLEG00000015819	6 retrocopies	retro_nleu_1250, retro_nleu_1657, retro_nleu_2096, retro_nleu_2108, retro_nleu_555, retro_nleu_770,
Otolemur garnettii	ENSOGAG00000010097	5 retrocopies	retro_ogar_1161, retro_ogar_158, retro_ogar_1848, retro_ogar_2837, retro_ogar_34,
Pongo abelii	ENSPPYG00000017543	4 retrocopies	retro_pabe_131, retro_pabe_139, retro_pabe_1755, retro_pabe_496,
Pan troglodytes	ENSPTRG00000019209	9 retrocopies	retro_ptro_129, retro_ptro_1331, retro_ptro_2065, retro_ptro_2259, retro_ptro_2750, retro_ptro_2838, retro_ptro_3046, retro_ptro_3167, retro_ptro_809,
Sus scrofa	ENSSSCG00000007743	1 retrocopy	retro_sscr_515,
Ictidomys tridecemlineatus	ENSSTOG00000010512	3 retrocopies	retro_itri_1870, retro_itri_670, retro_itri_671,
Tupaia belangeri	ENSTBEG00000012905	15 retrocopies	retro_tbel_1728, retro_tbel_1891, retro_tbel_2513, retro_tbel_2593, retro_tbel_2596, retro_tbel_2658, retro_tbel_3331, retro_tbel_3764, retro_tbel_3777, retro_tbel_3954, retro_tbel_4082, retro_tbel_4368, retro_tbel_4487, retro_tbel_4728, retro_tbel_817,
Tursiops truncatus	ENSTTRG00000015185	1 retrocopy	retro_ttru_520,
Vicugna pacos	ENSVPAG00000006104	1 retrocopy	retro_vpac_48,