RetrogeneDB ID: retro_nleu_515

Retrocopy location

• Organism: Gibbon (Nomascus leucogenys)
• Coordinates: GL397266.1:20608385..20609381(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MEST
• Ensembl ID: ENSNLEG00000012841
• Aliases: None
• Description: None

Sequence

>retro_nleu_515
GTGCGCAGAGATGGTCTCCGCAGGATGAGGGAGTGGTGGGTCCAGGTGGGTCTGTGGGCAGTGCTCCTGCTTGCTGCGTT
CCTGCACATCCCACTCACTGAGCTCTCACCTGATCTTCACTCATGCAAGTCTTCAGGCAGGTTTTTCACTTACAAGGGAC
TGCGTATCTTCTACCAAGACTCTGTGGGTGTGGTTGGAAGTCAGGAGACAGTTGTGGTTTTACACGTTTTCCAACATCCA
GCTACGATTGGTACAAGATTTGGGAAGCTCTGACCTTGAGGTTTCATCGGGTTATTGCCCTTGATTTCTTAGGTGTTGGC
TTCAGTGACAAACCGAGACCACATCACTATTCCATATTTGAGCAGGTCAGCATCGTGGAAGCGCTTTAGCGGCATCTGGG
TCTCTAGAACCGCGGGATCAAGTCTTAGGACTATGGAGATAATTGTTGCTCAGGAGCTTCTCTACAGGTACAAGCAGAAT
CGATCTGGTCGGCATAACATAAAGAGTCTCTGTCTGTCAAATGGAGGTATCTTTCCTGAGACTCACCGTCCACTCCTTCT
CCAAAAGCTACTCAAGGATGGAGGTGTGCCATCACCCATCCTCACACGACTGATGAACTTCTTCGTATTCTCTCAAGGTC
TCACGCCAGTCTTTGGGCCGTATAGTTGGCCCTCTGAGAGTGAGCTGTGGGACATGTGGGCAGGGATCCGCAACAATGAT
GGGAACTTAGTCATTGACGGTCTCTTACAGTGCATCAATCAGAGGAAGAAGCTCAGAAGGCGCTGGGTGGGAGCTCTTGC
CTCTGTAACTATCCCCATTCATTTTATCTATGGGCCATTGGATCCTGTAAATCCCTGTCCAGACTTTTTGGAGCTGTATG
GGAAAACGCTGCCGCGGTCCACAGTGTCGATTCTGGATGACCACATTAGCCACTATCCACAGCTAGAGGATGCCATTGGC
TTCTTGAATGCATACATGGGCTTCATCAACTCCTTC

Alignment

ORF - retro_nleu_515 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 88.1 %
• Parental protein coverage: 99.7 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  VRRDRLRRMREWWVQVGLLAVPLLAAYLHIPPPQLSPALHSWKSSGKFFTYKGLRIFYQDSVGVVGSPEI
          VRRD.LRRMREWWVQVGL.AV.LLAA.LHIP...LSP.LHS.KSSG.FFTYKGLRIFYQDSVGVVGS.E.
Retrocopy VRRDGLRRMREWWVQVGLWAVLLLAAFLHIPLTELSPDLHSCKSSGRFFTYKGLRIFYQDSVGVVGSQET

Parental  VVLLH-GFPTSSYDWYKIWEGLTLRFHRVIALDFLGFGFSDKPRPHHYSIFEQASIVEALLRHLGLQNRR
          VV.LH..FPTSSYDWYKIWE.LTLRFHRVIALDFLG.GFSDKPRPHHYSIFEQ.SIVEAL.RHLGL.NR.
Retrocopy VVVLH<RFPTSSYDWYKIWEALTLRFHRVIALDFLGVGFSDKPRPHHYSIFEQVSIVEAL*RHLGL*NRG

Parental  INLLSHDYGD-IVAQELLYRYKQNRSGRLTIKSLCLSNGGIFPETHRPLLLQKLLKDGGVLSPILTRLMN
          I...S.DYGD.IVAQELLYRYKQNRSGR..IKSLCLSNGGIFPETHRPLLLQKLLKDGGV.SPILTRLMN
Retrocopy IK--S*DYGD>IVAQELLYRYKQNRSGRHNIKSLCLSNGGIFPETHRPLLLQKLLKDGGVPSPILTRLMN

Parental  FFVFSRGLTPVFGPYTRPSESELWDMWAGIRNNDGNLVIDSLLQYINQRKKFRRRWVGALASVTIPIHFI
          FFVFS.GLTPVFGPY..PSESELWDMWAGIRNNDGNLVID.LLQ.INQRKK.RRRWVGALASVTIPIHFI
Retrocopy FFVFSQGLTPVFGPYSWPSESELWDMWAGIRNNDGNLVIDGLLQCINQRKKLRRRWVGALASVTIPIHFI

Parental  YGPLDPVNPYPEFLELYRKTLPRSTVSILDDHISHYPQLEDPMGFLNAYMGFINSF
          YGPLDPVNP.P.FLELY.KTLPRSTVSILDDHISHYPQLED..GFLNAYMGFINSF
Retrocopy YGPLDPVNPCPDFLELYGKTLPRSTVSILDDHISHYPQLEDAIGFLNAYMGFINSF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Nomascus leucogenys was not studied using RNA-Seq expression data.

ChIP-Seq

Nomascus leucogenys was not studied using ChIP-Seq data.

EST

Nomascus leucogenys was not studied using EST data.

TSS

Nomascus leucogenys was not studied using FANTOM5 data.

Lab

retro_nleu_515 was not experimentally validated.

Homology

Retrocopy orthology:

Nomascus leucogenys does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 14 parental genes, and 33 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000005659	2 retrocopies	retro_amel_1177, retro_amel_1874,
Callithrix jacchus	ENSCJAG00000010760	2 retrocopies	retro_cjac_1563, retro_cjac_3931,
Felis catus	ENSFCAG00000022984	5 retrocopies	retro_fcat_1067, retro_fcat_1645, retro_fcat_1693, retro_fcat_2004, retro_fcat_326,
Loxodonta africana	ENSLAFG00000006066	3 retrocopies	retro_lafr_578, retro_lafr_584, retro_lafr_748,
Macropus eugenii	ENSMEUG00000008227	1 retrocopy	retro_meug_885,
Microcebus murinus	ENSMICG00000006129	1 retrocopy	retro_mmur_1091,
Macaca mulatta	ENSMMUG00000009499	2 retrocopies	retro_mmul_1936, retro_mmul_94,
Nomascus leucogenys	ENSNLEG00000012841	3 retrocopies	retro_nleu_1065, retro_nleu_515 , retro_nleu_790,
Otolemur garnettii	ENSOGAG00000009224	1 retrocopy	retro_ogar_3464,
Pongo abelii	ENSPPYG00000018006	4 retrocopies	retro_pabe_2337, retro_pabe_2510, retro_pabe_2511, retro_pabe_866,
Pan troglodytes	ENSPTRG00000019698	2 retrocopies	retro_ptro_1769, retro_ptro_2045,
Sorex araneus	ENSSARG00000000502	1 retrocopy	retro_sara_352,
Ictidomys tridecemlineatus	ENSSTOG00000020977	2 retrocopies	retro_itri_1210, retro_itri_1610,
Tursiops truncatus	ENSTTRG00000004934	4 retrocopies	retro_ttru_1026, retro_ttru_1115, retro_ttru_1133, retro_ttru_1907,