RetrogeneDB ID: retro_ptro_116

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: X:57840080..57840857(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSPTRG00000028266
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: SPIN1
• Ensembl ID: ENSPTRG00000021088
• Aliases: None
• Description: None

Sequence

>retro_ptro_116
ATGAAGACCCCCAACGCACAGGAAGCCGAAGGGCAACAAACCAGGGCAGCTGCAGGACGGGCCACTGGGTCTGCAAACAT
GACAAAGAAAAAAGTCTCCCAAAAGAAGCAGAGAGGCAGACCTTCATCCCAGCCCCGCAGGAACATCGTGGGCTGCAGAA
TTTCTCATGCATGGAAGGAAGGAGATGAGCCCATCATGCAGTGGAAAGGAACCGTTCTGGATCAGGTGCCTATAAATCCC
TCTCTTTATCTGGTGAAATATGATGGAATTGACTGTGTCTATGGATTGGAACTTCACAGAGATGAAAGGGTTTTGTCTCT
TAAAATTCTTTCTGACAGGGTGGCATCATCTCACATTAGTGATGCCAACCTTGCAAATACCATAATTGGCAAAGCAGTGG
AACACATGTTTGAGGGAGAGCATGGTTCTAAGGATGAATGGAGGGGGATGGTCTTAGCTCAAGCACCTATCATGAAAGCC
TGGTTTTATATTACCTATGAGAAAGATCCTGTCTTGTACATGTACCAGCTTCTAGATGATTATAAGGAAGGTGACCTCTG
CATCATGCCAGAATCCAGTGAGTCTCCTCCAACAGAGAGGGAGCCAGGAGGAGTTGTAGATGGCCTAATAGGTAAGCATG
TGGAATATACCAAAGAAGATGGCTCCAAAAGGATCGGCATGGTCATTCACCAAGTGGAAACCAAACCCTCTGTGTATTTC
ATCAAGTTTGATGATGATTTCCATATCTATGTCTACGATTTGGTGAAAAAGTCCTAA

Alignment

ORF - retro_ptro_116 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 73.76 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MKTPFGK-TPGQRSRADAGHAGVSANMMKKRTSHKKHRSSVGPSKPVSQPRRNIVGCRIQHGWKEGNGPV
          MKTP......GQ..RA.AG.A..SAN.M.K.....K.........P.SQPRRNIVGCRI.H.WKEG..P.
Retrocopy MKTPNAQEAEGQQTRAAAGRATGSAN-MTKKKVSQKKQRG----RPSSQPRRNIVGCRISHAWKEGDEPI

Parental  TQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELNKDERVSALEVLPDRVATSRISDAHLADTMIGKAVEH
          .QWKGTVLDQVP.NPSLYL.KYDG.DCVYGLEL..DERV..L..L.DRVA.S.ISDA.LA.T.IGKAVEH
Retrocopy MQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHISDANLANTIIGKAVEH

Parental  MFETEDGSKDEWRGMVLARAPVMNTWFYITYEKDPVLYMYQLLDDYKEGDLRIMPDSNDSPPAEREPGEV
          MFE.E.GSKDEWRGMVLA.AP.M..WFYITYEKDPVLYMYQLLDDYKEGDL.IMP.S..SPP.EREPG.V
Retrocopy MFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDDYKEGDLCIMPESSESPPTEREPGGV

Parental  VDSLVGKQVEYAKEDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKTS
          VD.L.GK.VEY.KEDGSKR.GMVIHQVE.KPSVYFIKFDDDFHIYVYDLVK.S
Retrocopy VDGLIGKHVEYTKEDGSKRIGMVIHQVETKPSVYFIKFDDDFHIYVYDLVKKS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	7.42 RPM	107.46 RPM
SRP007412_cerebellum	5.63 RPM	89.12 RPM
SRP007412_heart	2.27 RPM	36.46 RPM
SRP007412_kidney	3.22 RPM	94.90 RPM
SRP007412_liver	1.47 RPM	16.14 RPM
SRP007412_testis	2.85 RPM	124.25 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_116 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_116 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_116 has 0 orthologous retrocopies within eutheria group .

---

Parental genes homology:

Parental genes homology involve 23 parental genes, and 49 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000003301	4 retrocopies	retro_amel_1831, retro_amel_1879, retro_amel_38, retro_amel_41,
Bos taurus	ENSBTAG00000003044	4 retrocopies	retro_btau_1678, retro_btau_1841, retro_btau_187, retro_btau_553,
Canis familiaris	ENSCAFG00000002208	3 retrocopies	retro_cfam_153, retro_cfam_2095, retro_cfam_59,
Choloepus hoffmanni	ENSCHOG00000006983	2 retrocopies	retro_chof_1343, retro_chof_1852,
Callithrix jacchus	ENSCJAG00000017452	1 retrocopy	retro_cjac_227,
Cavia porcellus	ENSCPOG00000000743	1 retrocopy	retro_cpor_123,
Echinops telfairi	ENSETEG00000013719	1 retrocopy	retro_etel_28,
Felis catus	ENSFCAG00000007197	2 retrocopies	retro_fcat_32, retro_fcat_70,
Homo sapiens	ENSG00000106723	1 retrocopy	retro_hsap_64,
Loxodonta africana	ENSLAFG00000027497	2 retrocopies	retro_lafr_18, retro_lafr_58,
Microcebus murinus	ENSMICG00000014510	1 retrocopy	retro_mmur_8,
Myotis lucifugus	ENSMLUG00000008516	2 retrocopies	retro_mluc_132, retro_mluc_1626,
Mustela putorius furo	ENSMPUG00000008585	1 retrocopy	retro_mputfur_139,
Mus musculus	ENSMUSG00000021395	3 retrocopies	retro_mmus_112, retro_mmus_16, retro_mmus_3351,
Oryctolagus cuniculus	ENSOCUG00000011880	1 retrocopy	retro_ocun_63,
Otolemur garnettii	ENSOGAG00000002166	2 retrocopies	retro_ogar_2327, retro_ogar_9,
Procavia capensis	ENSPCAG00000015800	1 retrocopy	retro_pcap_14,
Pongo abelii	ENSPPYG00000019355	1 retrocopy	retro_pabe_33,
Pan troglodytes	ENSPTRG00000021088	2 retrocopies	retro_ptro_116 , retro_ptro_95,
Pteropus vampyrus	ENSPVAG00000013391	3 retrocopies	retro_pvam_2, retro_pvam_22, retro_pvam_858,
Rattus norvegicus	ENSRNOG00000011119	4 retrocopies	retro_rnor_1483, retro_rnor_1531, retro_rnor_281, retro_rnor_2818,
Ictidomys tridecemlineatus	ENSSTOG00000029107	1 retrocopy	retro_itri_136,
Tursiops truncatus	ENSTTRG00000005602	6 retrocopies	retro_ttru_1061, retro_ttru_13, retro_ttru_1452, retro_ttru_1506, retro_ttru_1669, retro_ttru_1698,