RetrogeneDB ID: retro_ptro_529

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 11:3295146..3295480(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: NDUFA5
• Ensembl ID: ENSPTRG00000019637
• Aliases: None
• Description: Pan troglodytes NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa (NDUFA5), nuclear gene encoding mitochondrial protein, mRNA. [Source:RefSeq mRNA;Acc:NM_001071797]

Sequence

>retro_ptro_529
GGTGTGCTGAAGAAGACCACTGCCCTTGTGGGACTGGCTATATTCAGAGTCCACATGAGAGGCTAAGAATATTGTACACA
GAGATTCTTGATGTTCTTGAGCAAATCCCTAAAAATGCAGCATATAGAAAGTACATAGAACAGATTACAAATGAGAAGCC
GGCTGTGGTTAAAGTGGAAACAGATGTTAAAAAATTAGAAGACCAACTTCAAGGTGGTCAAATAGAAGAGGTGATTCTTC
ATGCTGAACATGGACTAAGTCTGGCAAGAGAAATGAGGCCGTGGAAAGCCTGGGAGCCATTAGTGGAGAGCCTCTTACCA
ATCTGTGGAAATGG

Alignment

ORF - retro_ptro_529 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 78.07 %
• Parental protein coverage: 96.55 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  GVLKKTTGLVGLAV-CNTPHERLRILYTKILDVLEEIPKNAAYRKYTEQITNEKLAMVKAEPDVKKLEDQ
          GVLKKTT.LVGLA.....PHERLRILYT.ILDVLE.IPKNAAYRKY.EQITNEK.A.VK.E.DVKKLEDQ
Retrocopy GVLKKTTALVGLAI<IQSPHERLRILYTEILDVLEQIPKNAAYRKYIEQITNEKPAVVKVETDVKKLEDQ

Parental  LQGGQLEEVILQAEHELNLARKMREWKLWEPLVE-EPPADQWKW
          LQGGQ.EEVIL.AEH.L.LAR.MR.WK.WEPLVE.EP....WKW
Retrocopy LQGGQIEEVILHAEHGLSLAREMRPWKAWEPLVE<EPLTNLWKW

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	37.93 RPM
SRP007412_cerebellum	0.00 RPM	25.74 RPM
SRP007412_heart	0.00 RPM	72.17 RPM
SRP007412_kidney	0.00 RPM	33.79 RPM
SRP007412_liver	0.00 RPM	13.98 RPM
SRP007412_testis	0.00 RPM	15.81 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

1 EST(s) were mapped to retro_ptro_529 retrocopy

EST ID	Start	End	Identity	Match	Mis-match	Score
CB296748	3295202	3295320	95	112	6	106

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_529 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_529 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_746
Homo sapiens	retro_hsap_745
Gorilla gorilla	retro_ggor_624

---

Parental genes homology:

Parental genes homology involve 17 parental genes, and 79 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000004512	2 retrocopies	retro_amel_1543, retro_amel_695,
Bos taurus	ENSBTAG00000009334	5 retrocopies	retro_btau_1258, retro_btau_1613, retro_btau_537, retro_btau_808, retro_btau_950,
Canis familiaris	ENSCAFG00000025112	4 retrocopies	retro_cfam_302, retro_cfam_445, retro_cfam_882, retro_cfam_921,
Callithrix jacchus	ENSCJAG00000017449	1 retrocopy	retro_cjac_65,
Felis catus	ENSFCAG00000027125	5 retrocopies	retro_fcat_1081, retro_fcat_1278, retro_fcat_244, retro_fcat_550, retro_fcat_799,
Homo sapiens	ENSG00000128609	10 retrocopies	retro_hsap_1065, retro_hsap_1687, retro_hsap_2671, retro_hsap_3218, retro_hsap_3627, retro_hsap_3950, retro_hsap_3997, retro_hsap_4248, retro_hsap_745, retro_hsap_746,
Gorilla gorilla	ENSGGOG00000022922	9 retrocopies	retro_ggor_1264, retro_ggor_1864, retro_ggor_2185, retro_ggor_2447, retro_ggor_2654, retro_ggor_2683, retro_ggor_2848, retro_ggor_624, retro_ggor_840,
Loxodonta africana	ENSLAFG00000030971	1 retrocopy	retro_lafr_275,
Monodelphis domestica	ENSMODG00000015384	4 retrocopies	retro_mdom_1292, retro_mdom_1429, retro_mdom_1804, retro_mdom_525,
Mustela putorius furo	ENSMPUG00000006811	4 retrocopies	retro_mputfur_1151, retro_mputfur_1353, retro_mputfur_683, retro_mputfur_939,
Mus musculus	ENSMUSG00000023089	2 retrocopies	retro_mmus_2951, retro_mmus_853,
Otolemur garnettii	ENSOGAG00000033137	6 retrocopies	retro_ogar_1346, retro_ogar_1504, retro_ogar_1791, retro_ogar_2047, retro_ogar_2676, retro_ogar_649,
Pongo abelii	ENSPPYG00000017956	10 retrocopies	retro_pabe_1389, retro_pabe_2216, retro_pabe_2666, retro_pabe_2794, retro_pabe_2795, retro_pabe_2975, retro_pabe_3283, retro_pabe_3390, retro_pabe_3728, retro_pabe_887,
Pan troglodytes	ENSPTRG00000019637	10 retrocopies	retro_ptro_1141, retro_ptro_1800, retro_ptro_2235, retro_ptro_2452, retro_ptro_2682, retro_ptro_2714, retro_ptro_2888, retro_ptro_2937, retro_ptro_529 , retro_ptro_725,
Rattus norvegicus	ENSRNOG00000005698	3 retrocopies	retro_rnor_1041, retro_rnor_2154, retro_rnor_2290,
Sus scrofa	ENSSSCG00000016607	2 retrocopies	retro_sscr_1029, retro_sscr_693,
Ictidomys tridecemlineatus	ENSSTOG00000027404	1 retrocopy	retro_itri_911,