RetrogeneDB ID: retro_amel_219

Retrocopy location

• Organism: Panda (Ailuropoda melanoleuca)
• Coordinates: GL192356.1:250909..251551(+)
• Located in intron of: ENSAMEG00000015003

Retrocopy information

• Ensembl ID: ENSAMEG00000015078
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: CAPZA1
• Ensembl ID: ENSAMEG00000003570
• Aliases: None
• Description: capping protein (actin filament) muscle Z-line, alpha 1 [Source:HGNC Symbol;Acc:1488]

Sequence

>retro_amel_219
GAGCAGGTCTTAATTAGAGAACACGTGACCTGGGTAATAGCAGATTTTTAGATCCAAGTAACAAAATTTCCTTTAAGTTT
GATCAGTCATGGAAAGAAGCAAGTGACCCAGAGAACGTAGATGGAGGTCTGAACTCTTGGAGAGAATCTTGTGACAGTGC
TTTAAAGGCCTATGTGAAAGATCGTTATTCCAACAGCTTCTGTACTGTTCATGCTAAAACTGTAGATGGGGTGTTGCAGA
CCATCACTGCATATATTGAAAAACCACCAGTTTTAGCTTAAAAACTTCTGGAATGGTTGTTGGAGATCAGAGTGGAAGTT
CACTGTCACACCACCTACAGCCCAGGTGGTCGGAGTACTTAAGATTCAGGTTCACTGCTATGAAGATGGCAATATTCAGT
TGGTTAGTCATAAAAATGTGCAGGATTCAGTAACCATTGCAAATGAAGTCCAAACTGCCAAGGAGTTTATTAAAACCATA
GAGCATGAAGAAAACGAATACCAGACAGCATTTAGTGAAAACTGTCAGACAATGTCATACACCACATTTAAGGCCTTGCA
CTGGCAGCTTCCAGTTACTTGCACCAAAATTGACTGGAACAAGACACTCAGCTACAAGATTGGTAAAGCAATGCAGAATG
CT

Alignment

ORF - retro_amel_219 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 80.28 %
• Parental protein coverage: 75.17 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  DQVLITEH-GDLGNSRFLDPRNKISFKFDHLRKEACDPQPEDVDGGLKSWRESCDSALRAYVKDHYSNGF
          .QVLI.EH..DLGNSRFLDP.NKISFKFD...KEA.DP..E.VDGGL.SWRESCDSAL.AYVKD.YSN.F
Retrocopy EQVLIREH<RDLGNSRFLDPSNKISFKFDQSWKEASDP--ENVDGGLNSWRESCDSALKAYVKDRYSNSF

Parental  CTVYAKTIDGQ-QTIIACIE-SHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVS
          CTV.AKT.DG..QTI.A.IE..HQF..KNFWNG.WRSEWKFT.TPPTAQVVGVLKIQVH.YEDGN.QLVS
Retrocopy CTVHAKTVDGVLQTITAYIE>NHQF*LKNFWNGCWRSEWKFTVTPPTAQVVGVLKIQVHCYEDGNIQLVS

Parental  HKDVQDSVTVSNEVQTAKEFIKIIEHAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYK
          HK.VQDSVT..NEVQTAKEFIK.IEH.ENEYQTA.SEN.QTMS.TTFKAL..QLPVT.TKIDWNK.LSYK
Retrocopy HKNVQDSVTIANEVQTAKEFIKTIEHEENEYQTAFSENCQTMSYTTFKALHWQLPVTCTKIDWNKTLSYK

Parental  IGKEMQNA
          IGK.MQNA
Retrocopy IGKAMQNA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Ailuropoda melanoleuca was not studied using RNA-Seq expression data.

ChIP-Seq

Ailuropoda melanoleuca was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_amel_219 retrocopy.

TSS

Ailuropoda melanoleuca was not studied using FANTOM5 data.

Lab

retro_amel_219 was not experimentally validated.

Homology

Retrocopy orthology:

Ailuropoda melanoleuca does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 24 parental genes, and 56 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000003570	1 retrocopy	retro_amel_219 ,
Choloepus hoffmanni	ENSCHOG00000004131	8 retrocopies	retro_chof_1008, retro_chof_1419, retro_chof_1499, retro_chof_1704, retro_chof_1861, retro_chof_2129, retro_chof_625, retro_chof_711,
Callithrix jacchus	ENSCJAG00000013548	3 retrocopies	retro_cjac_2259, retro_cjac_2850, retro_cjac_4125,
Cavia porcellus	ENSCPOG00000014532	1 retrocopy	retro_cpor_1155,
Dipodomys ordii	ENSDORG00000000671	3 retrocopies	retro_dord_224, retro_dord_265, retro_dord_44,
Felis catus	ENSFCAG00000013303	2 retrocopies	retro_fcat_700, retro_fcat_746,
Homo sapiens	ENSG00000116489	2 retrocopies	retro_hsap_2338, retro_hsap_4871,
Gorilla gorilla	ENSGGOG00000023677	1 retrocopy	retro_ggor_1216,
Latimeria chalumnae	ENSLACG00000017963	1 retrocopy	retro_lcha_20,
Myotis lucifugus	ENSMLUG00000009796	1 retrocopy	retro_mluc_2483,
Macaca mulatta	ENSMMUG00000015668	2 retrocopies	retro_mmul_2612, retro_mmul_942,
Mustela putorius furo	ENSMPUG00000004977	1 retrocopy	retro_mputfur_616,
Mus musculus	ENSMUSG00000070372	4 retrocopies	retro_mmus_179, retro_mmus_1828, retro_mmus_3370, retro_mmus_349,
Nomascus leucogenys	ENSNLEG00000004191	1 retrocopy	retro_nleu_1689,
Oryctolagus cuniculus	ENSOCUG00000000270	6 retrocopies	retro_ocun_1315, retro_ocun_1417, retro_ocun_1787, retro_ocun_301, retro_ocun_527, retro_ocun_555,
Otolemur garnettii	ENSOGAG00000014074	4 retrocopies	retro_ogar_1640, retro_ogar_2159, retro_ogar_3217, retro_ogar_845,
Pongo abelii	ENSPPYG00000001021	2 retrocopies	retro_pabe_2116, retro_pabe_3789,
Pan troglodytes	ENSPTRG00000001110	2 retrocopies	retro_ptro_1710, retro_ptro_3245,
Rattus norvegicus	ENSRNOG00000013538	1 retrocopy	retro_rnor_77,
Sorex araneus	ENSSARG00000001278	1 retrocopy	retro_sara_166,
Ictidomys tridecemlineatus	ENSSTOG00000015956	1 retrocopy	retro_itri_1044,
Tupaia belangeri	ENSTBEG00000001727	5 retrocopies	retro_tbel_1870, retro_tbel_3525, retro_tbel_4327, retro_tbel_638, retro_tbel_868,
Tarsius syrichta	ENSTSYG00000006259	2 retrocopies	retro_tsyr_179, retro_tsyr_471,
Vicugna pacos	ENSVPAG00000005361	1 retrocopy	retro_vpac_579,