RetrogeneDB ID: retro_cfam_711

Retrocopy location

• Organism: Dog (Canis familiaris)
• Coordinates: 16:42036531..42037743(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSCAFG00000028501
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: SF3B4
• Ensembl ID: ENSCAFG00000011617
• Aliases: None
• Description: splicing factor 3b, subunit 4, 49kDa [Source:HGNC Symbol;Acc:10771]

Sequence

>retro_cfam_711
ATGGCAGCAGGGTGGATCTGAAGCAGAACCAGGATGCCACTGTCTACATCGGGGGCCTGGATGAGAAGGTTGGCAAACCA
CTGCTGTGGGAGCTTTTTCTCCAGGCAGGGCCAGTAGTCAGCACCCACATGCCAAAGGATAGAGTCACAGGTCAGCACCA
AGGCTATGGCTTTGTGGAATTCCTGAGTGGGGAAGATGCTGACTGTGCCATTAAGATCATGAACATGATCAAACTCTATG
GGAAGCCAATAAGAGTGAACAAGACATCGGCTCACAACAGCAACCTGGACGTGGGGGCCAACATTTTCATTGACAATCTG
GACCCAGGGATTGATGGGAATCTGCTTCATGATTCCTTCAACGCCTTCGGGGTCATCTTACAACCCCCCAAGATTATGTG
GGACCCTGATACAGGCAACTCCAAAGGTTATGCCTTTATTAATTTTGCGTCATTTGATGCTTCGGATGCAGTTACCGAGG
CCATGAACAGGCAGTATCTTGGTAACCGCCCCATCACTGCGTCCTATGCCTTCAAGGACTTCAAGGGGTTGCGCCACGGC
TCAGCAGTTGAACGACTTCTGGCAGCCCAGAACCCACTCTCCCAAGCTGACCACCCTCATCAGCTGTTTGCAGACGCACC
CCCTCTGCCTTCAGCCCCCAATCCTGTCGTTTCATCTTTGGGGTCTGGGCTCCCTCCACCAGGCATGCCTCCTCCTGGGT
CCTTCGCACCCCTAGTGCTGCCTCCTGGAGCCCTTCCACCTGGGATACCCCCAGCCATGCCCCCCGACACCTATGCCTCC
GAGGGCTGGAGGACACAGTCCACCATCAGCAGGAATCCCAGGGGCCAGACGTCCTGGACATGGACACTCGCATCCTCACC
CATTCCCACCGAGTGGGATGCCCCGTCCAGGGATGTCTCAGATGCAGCTGGCCCACCATGGCCCTCATGGCCCAGGCCAC
CCACATGCTGGGCCCCCAGGCACTGGGGGGCATCTGCCACCCCAACCACCACCTGGAATGCCTCATCCTGGGCCTCCTCC
AATGGACATGCCCCCTTGAGGGCCTCTGTATGGATCTCCCATGGGTCACCCAGGTCCCATGCCTCCACATGGGATGCTTG
GACCTCCTCCACTGGTGCCTCCTTGTGGATACACTGGGCCTCCATGATCCCCACCCTCTGGCTACCAGCGGGGACCCCTG
CCTCCACCCAGA

Alignment

ORF - retro_cfam_711 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 85.5 %
• Parental protein coverage: 95.52 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MAAGPISER-NQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADY
          MAAG.I..R.NQDATVY.GGLDEKV..PLLWELFLQAGPVV.THMPKDRVTGQHQGYGFVEFLS.EDAD.
Retrocopy MAAGWI*SR<NQDATVYIGGLDEKVGKPLLWELFLQAGPVVSTHMPKDRVTGQHQGYGFVEFLSGEDADC

Parental  AIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTG
          AIKIMNMIKLYGKPIRVNK.SAHN.NLDVGANIFI.NLDP.ID..LL.D.F.AFGVILQ.PKIM.DPDTG
Retrocopy AIKIMNMIKLYGKPIRVNKTSAHNSNLDVGANIFIDNLDPGIDGNLLHDSFNAFGVILQPPKIMWDPDTG

Parental  NSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQ
          NSKGYAFINFASFDASDA..EAMN.QYL.NRPIT.SYAF.KD.KG.RHGSA.ERLLAAQNPLSQAD.PHQ
Retrocopy NSKGYAFINFASFDASDAVTEAMNRQYLGNRPITASYAF-KDFKGLRHGSAVERLLAAQNPLSQADHPHQ

Parental  LFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAM-PPPPMPPGAGGHGPPSA
          LFADAPP.PSAPNPVVSSLGSGLPPPGMPPPGSF.P.V.PPGALPPGIPPAM.PP.PMPP.AGGH.PPSA
Retrocopy LFADAPPLPSAPNPVVSSLGSGLPPPGMPPPGSFAPLVLPPGALPPGIPPAM>PPTPMPPRAGGHSPPSA

Parental  GTPGAGHPGHGHSHPHPFPPSGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPP
          G.PGA..PGHGHSHPHPFPPSGMP.PGMSQMQLAHHGPHG.GHPHAGPPG.GG..PP.PPPGMPHPGPPP
Retrocopy GIPGARRPGHGHSHPHPFPPSGMPRPGMSQMQLAHHGPHGPGHPHAGPPGTGGHLPPQPPPGMPHPGPPP

Parental  MGLPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPR
          M..PP.GP..GSPMGHPGPMPPHGM.GPPPL.PP.GYTGPP..PP.GYQRGPLPPPR
Retrocopy MDMPP*GPLYGSPMGHPGPMPPHGMLGPPPLVPPCGYTGPP*SPPSGYQRGPLPPPR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012049_cerebellum	0.00 RPM	40.36 RPM
SRP017611_brain	0.00 RPM	20.96 RPM
SRP017611_kidney	0.00 RPM	23.51 RPM
SRP017611_liver	0.00 RPM	8.77 RPM

ChIP-Seq

Canis familiaris was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cfam_711 retrocopy.

TSS

Canis familiaris was not studied using FANTOM5 data.

Lab

retro_cfam_711 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cfam_711 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 16 parental genes, and 23 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000012495	2 retrocopies	retro_btau_1385, retro_btau_592,
Canis familiaris	ENSCAFG00000011617	3 retrocopies	retro_cfam_585, retro_cfam_711 , retro_cfam_729,
Canis familiaris	ENSCAFG00000013514	1 retrocopy	retro_cfam_1021,
Callithrix jacchus	ENSCJAG00000000793	3 retrocopies	retro_cjac_1297, retro_cjac_1909, retro_cjac_638,
Cavia porcellus	ENSCPOG00000008267	1 retrocopy	retro_cpor_234,
Echinops telfairi	ENSETEG00000008963	1 retrocopy	retro_etel_1310,
Homo sapiens	ENSG00000143368	1 retrocopy	retro_hsap_1356,
Gorilla gorilla	ENSGGOG00000004761	1 retrocopy	retro_ggor_1056,
Macaca mulatta	ENSMMUG00000007256	1 retrocopy	retro_mmul_2191,
Mustela putorius furo	ENSMPUG00000005563	2 retrocopies	retro_mputfur_1105, retro_mputfur_648,
Oryctolagus cuniculus	ENSOCUG00000004614	1 retrocopy	retro_ocun_1239,
Pongo abelii	ENSPPYG00000000912	1 retrocopy	retro_pabe_1124,
Pan troglodytes	ENSPTRG00000001243	1 retrocopy	retro_ptro_930,
Pteropus vampyrus	ENSPVAG00000014171	1 retrocopy	retro_pvam_931,
Rattus norvegicus	ENSRNOG00000021181	1 retrocopy	retro_rnor_2350,
Ictidomys tridecemlineatus	ENSSTOG00000000684	2 retrocopies	retro_itri_1153, retro_itri_487,