RetrogeneDB ID: retro_ptro_2683

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 8:48537431..48537888(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PDCD10
• Ensembl ID: ENSPTRG00000015598
• Aliases: None
• Description: None

Sequence

>retro_ptro_2683
GTAAATCTGTCTGCAGCTCAGATACTGAGAGTGGCTTTCATTAAGGCCAATAAAGGAAACCCTGGTCTCACACAATACAT
TGTTTTGGCAACTTTAGAGAAAAAAAATATAAACATTAAGATCACAGGATTTCTTCTTATGGCAGCTGTTAATGTATAAT
AGTAGATAATTGAATGACTAGAGCCAGAATTCCAGGATGTAAATGAAAGTCACAAGCACTTATACAAATTCTCAGTAAGT
TTCCAGTGAGCTCAATGACAGAGTGAGGATTCTGTAGACAATTAAGGATATAAAGAGTGAAATAAAAGAGCTCGATATAG
TGAATAATGTCTTCAAGAAATATCAATACCACAACTACGGGGCACTTGAACACCAAAAGAAAGTATTTTTAAAGTATTCT
AAAAGTTTCAATGGTATTCTGAAAACTTATTTCAAAGATGACAAAGCAACAAATGTT

Alignment

ORF - retro_ptro_2683 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 66.24 %
• Parental protein coverage: 73.11 %
• Number of stop codons detected: 5
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  VNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVEVNFTESLLRMAADDVEEYMIERPEPEFQDLNE
          VNLSAAQ.LR.AFIKA.K.NPGLTQ.I....LE........T..LL.MAA..V....IE..EPEFQD.NE
Retrocopy VNLSAAQILRVAFIKANKGNPGLTQYIVLATLEXXXINIKITGFLL-MAAVNV***IIE*LEPEFQDVNE

Parental  -KARALKQILSKIP-DEINDRVRFLQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKYSKS
          .K..AL.QILSK.P..E.NDRVR.L.TIKDI.S.IKEL.D.VNNVFKKYQY.N..ALEHQKK.F.KYSKS
Retrocopy <KSQALIQILSKFP<SELNDRVRIL*TIKDIKSEIKEL-DIVNNVFKKYQYHNYGALEHQKKVFLKYSKS

Parental  FSDTLKTYFKDGKAINV
          F...LKTYFKD.KA.NV
Retrocopy FNGILKTYFKDDKATNV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	10.89 RPM
SRP007412_cerebellum	0.00 RPM	7.85 RPM
SRP007412_heart	0.00 RPM	11.25 RPM
SRP007412_kidney	0.00 RPM	17.78 RPM
SRP007412_liver	0.00 RPM	12.73 RPM
SRP007412_testis	0.00 RPM	34.78 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_2683 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_2683 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_2683 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3953
Gorilla gorilla	retro_ggor_2656
Pongo abelii	retro_pabe_3257
Macaca mulatta	retro_mmul_2288

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Parental genes homology:

Parental genes homology involve 24 parental genes, and 38 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000002181	1 retrocopy	retro_amel_420,
Bos taurus	ENSBTAG00000031709	2 retrocopies	retro_btau_1623, retro_btau_713,
Canis familiaris	ENSCAFG00000014569	2 retrocopies	retro_cfam_1988, retro_cfam_687,
Callithrix jacchus	ENSCJAG00000002763	2 retrocopies	retro_cjac_1442, retro_cjac_4178,
Dasypus novemcinctus	ENSDNOG00000015854	1 retrocopy	retro_dnov_351,
Homo sapiens	ENSG00000114209	1 retrocopy	retro_hsap_3953,
Gorilla gorilla	ENSGGOG00000008621	1 retrocopy	retro_ggor_2656,
Loxodonta africana	ENSLAFG00000006823	1 retrocopy	retro_lafr_409,
Microcebus murinus	ENSMICG00000007004	1 retrocopy	retro_mmur_1008,
Myotis lucifugus	ENSMLUG00000016978	1 retrocopy	retro_mluc_1331,
Macaca mulatta	ENSMMUG00000005938	2 retrocopies	retro_mmul_1090, retro_mmul_2288,
Mustela putorius furo	ENSMPUG00000017075	1 retrocopy	retro_mputfur_298,
Mus musculus	ENSMUSG00000027835	1 retrocopy	retro_mmus_2113,
Nomascus leucogenys	ENSNLEG00000004874	1 retrocopy	retro_nleu_532,
Otolemur garnettii	ENSOGAG00000013887	1 retrocopy	retro_ogar_540,
Oreochromis niloticus	ENSONIG00000005553	1 retrocopy	retro_onil_40,
Procavia capensis	ENSPCAG00000010385	1 retrocopy	retro_pcap_283,
Pongo abelii	ENSPPYG00000029750	1 retrocopy	retro_pabe_3257,
Pan troglodytes	ENSPTRG00000015598	1 retrocopy	retro_ptro_2683 ,
Sarcophilus harrisii	ENSSHAG00000005443	1 retrocopy	retro_shar_414,
Ictidomys tridecemlineatus	ENSSTOG00000028442	3 retrocopies	retro_itri_1208, retro_itri_1377, retro_itri_322,
Tupaia belangeri	ENSTBEG00000000240	9 retrocopies	retro_tbel_1498, retro_tbel_1690, retro_tbel_2223, retro_tbel_2903, retro_tbel_3430, retro_tbel_3898, retro_tbel_3900, retro_tbel_4532, retro_tbel_95,
Tarsius syrichta	ENSTSYG00000000708	1 retrocopy	retro_tsyr_1786,
Tursiops truncatus	ENSTTRG00000016315	1 retrocopy	retro_ttru_635,