RetrogeneDB ID: retro_ptro_3132

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: X:74233019..74233469(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RPS7
• Ensembl ID: ENSPTRG00000011615
• Aliases: None
• Description: Pan troglodytes ribosomal protein S7 (RPS7), mRNA. [Source:RefSeq mRNA;Acc:NM_001252001]

Sequence

>retro_ptro_3132
TTACGGGCAGCCAAGGAAATTGAAGTTGTGGTGGTTCGAAAGCTTTCCATATTTTTTGTCCCGGTTCCTCACTGAAATCT
TTCCAGAAAAACCCAGTTCCAGCTGTACGCGATTGAAGAAAAAGTTCAGTGGAGCATATTTCTTAATCGCTCAGAGGAGG
AATTCTGCTTAAGCCAACTCAAAAAAGCCGTACAAAAAATAAAGCAAAGCGTCCCAGGAGCTGTACTCTCACAGCTGGGC
CATGATGCCATCCTTGAGGACTTGGTCTTCCCAAGCGGAAATTGTGGGCAAGAGAATCCACGTGAAACTGGGATGGCAGC
CACCTCATAAAGATTCATTTGGGACGAAGCACAGCAGAAACAATGTGGAACACAAGGTTGAACCCTTTTCTGGTGTCTAT
AAGAAGCTCATGGGCAAGGATGTTAATTTTAATTCCCAGAGTTTCAATTG

Alignment

ORF - retro_ptro_3132 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 74.21 %
• Parental protein coverage: 77.32 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 9

Retrocopy - Parental Gene Alignment:

Parental  ITAAKEIEVGGGRKAIIIFVPVPQ-LKSFQKIQVRLVRE-LEKKFSGKHVVFIAQRR-ILPKPTRKSRTK
          ..AAKEIEV...RK..I.FVPVP..LKSFQK..V..VR..L.KKFSG.....IAQRR.IL.KPT.KSRTK
Retrocopy LRAAKEIEVVVVRKLSIFFVPVPH<LKSFQKNPVPAVRD<LKKKFSGAYFL-IAQRR>ILLKPTQKSRTK

Parental  NKQKRPRSRTLTAV-HDAILEDLVFPS-EIVGKRIRVKL-DGSRLIKVHL-DKAQQ-NNVEHKVETFSGV
          NK.KRPRS.TLTA..HDAILEDLVFPS.EIVGKRI.VKL.DGS.LIK.HL.D.AQQ.NNVEHKVE.FSGV
Retrocopy NKAKRPRSCTLTAG>HDAILEDLVFPS>EIVGKRIHVKL>DGSHLIKIHL>DEAQQ>NNVEHKVEPFSGV

Parental  YKKLTGKDVNFE-FPEFQL
          YKKL.GKDVNF..FPEFQL
Retrocopy YKKLMGKDVNFN<FPEFQL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	79.49 RPM
SRP007412_cerebellum	0.00 RPM	27.07 RPM
SRP007412_heart	0.00 RPM	17.72 RPM
SRP007412_kidney	0.03 RPM	102.93 RPM
SRP007412_liver	0.00 RPM	30.70 RPM
SRP007412_testis	0.00 RPM	18.76 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_3132 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_3132 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_3132 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 21 parental genes, and 95 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000018435	2 retrocopies	retro_amel_391, retro_amel_914,
Bos taurus	ENSBTAG00000016224	5 retrocopies	retro_btau_1016, retro_btau_1046, retro_btau_1351, retro_btau_448, retro_btau_997,
Canis familiaris	ENSCAFG00000003263	1 retrocopy	retro_cfam_1798,
Callithrix jacchus	ENSCJAG00000016462	2 retrocopies	retro_cjac_16, retro_cjac_2287,
Cavia porcellus	ENSCPOG00000009795	2 retrocopies	retro_cpor_1139, retro_cpor_773,
Dasypus novemcinctus	ENSDNOG00000013285	14 retrocopies	retro_dnov_1091, retro_dnov_1351, retro_dnov_1388, retro_dnov_1459, retro_dnov_1688, retro_dnov_1849, retro_dnov_1940, retro_dnov_1970, retro_dnov_238, retro_dnov_2409, retro_dnov_558, retro_dnov_582, retro_dnov_623, retro_dnov_791,
Equus caballus	ENSECAG00000020253	2 retrocopies	retro_ecab_276, retro_ecab_396,
Loxodonta africana	ENSLAFG00000015087	11 retrocopies	retro_lafr_1223, retro_lafr_160, retro_lafr_217, retro_lafr_318, retro_lafr_319, retro_lafr_413, retro_lafr_514, retro_lafr_720, retro_lafr_786, retro_lafr_964, retro_lafr_970,
Myotis lucifugus	ENSMLUG00000006121	1 retrocopy	retro_mluc_1118,
Macaca mulatta	ENSMMUG00000011870	7 retrocopies	retro_mmul_1831, retro_mmul_1846, retro_mmul_1929, retro_mmul_23, retro_mmul_2403, retro_mmul_2540, retro_mmul_357,
Monodelphis domestica	ENSMODG00000014495	2 retrocopies	retro_mdom_662, retro_mdom_810,
Mus musculus	ENSMUSG00000061477	2 retrocopies	retro_mmus_271, retro_mmus_53,
Nomascus leucogenys	ENSNLEG00000015407	10 retrocopies	retro_nleu_1505, retro_nleu_1771, retro_nleu_1783, retro_nleu_2278, retro_nleu_2346, retro_nleu_2510, retro_nleu_2892, retro_nleu_3080, retro_nleu_817, retro_nleu_835,
Oryctolagus cuniculus	ENSOCUG00000008507	2 retrocopies	retro_ocun_203, retro_ocun_230,
Otolemur garnettii	ENSOGAG00000028165	1 retrocopy	retro_ogar_133,
Pongo abelii	ENSPPYG00000025872	12 retrocopies	retro_pabe_1033, retro_pabe_1555, retro_pabe_2506, retro_pabe_2982, retro_pabe_2983, retro_pabe_31, retro_pabe_313, retro_pabe_360, retro_pabe_3659, retro_pabe_3803, retro_pabe_499, retro_pabe_524,
Pan troglodytes	ENSPTRG00000011615	3 retrocopies	retro_ptro_202, retro_ptro_3132 , retro_ptro_58,
Rattus norvegicus	ENSRNOG00000008551	2 retrocopies	retro_rnor_39, retro_rnor_391,
Sus scrofa	ENSSSCG00000027353	5 retrocopies	retro_sscr_136, retro_sscr_137, retro_sscr_240, retro_sscr_364, retro_sscr_956,
Ictidomys tridecemlineatus	ENSSTOG00000024830	3 retrocopies	retro_itri_1147, retro_itri_1161, retro_itri_1215,
Tursiops truncatus	ENSTTRG00000001616	6 retrocopies	retro_ttru_1422, retro_ttru_1659, retro_ttru_1706, retro_ttru_301, retro_ttru_323, retro_ttru_773,