RetrogeneDB ID:

retro_mmus_1225

Retrocopy
location
Organism:Mouse (Mus musculus)
Coordinates:14:101343897..101345232(+)
Located in intron of:None
Retrocopy
information
Ensembl ID:None
Aliases:None
Status:NOVEL
Parental gene
information
Parental gene summary:
Parental gene symbol:Hspd1
Ensembl ID:ENSMUSG00000025980
Aliases:Hspd1, 60kDa, Hsp60
Description:heat shock protein 1 (chaperonin) [Source:MGI Symbol;Acc:MGI:96242]


Retrocopy-Parental alignment summary:






>retro_mmus_1225
TTTGGGAAGATCAGCAAAGGGGTTAATCCAGTGGAAATCCAGAGAGGTGTGATGTTGGCTGCCAACGCTGCAATTGCTGA
ACTTAAGAAATAATTTAAACCTGTGATAATCCCTGAAGAAATTGCTCAGGTTGCTTCAATTTCTGCAAATGGAGACAAAG
ACATTGGGAACATCATTTCTGATGCAATGAAAAAGGCTGGAAGAAAGGGTGCCATCACAGTGAAGGATGGGAAAACCCCT
GAATGATGAGCTAGAAATTACTGATGGTGTGAAGTTTGATAGAGGGTATATTTCCCCATATTTTATTAATACATCAAAAG
GCCAAAACTATGAATTCCAAGATGCCTATGTTTTGTTGAATGAGAAGAAAATTTCTAGTGTTCAGTCCATTGTACCTGCT
CTTGAAATTGCTAATGTTCACGGAAGCCCTTTGATCATAATGGCTGAATAAGTTGATGGAGAAGCTCTAAGTATACTGGT
TTGAACAGGCTAAAAGTTGGTCTTCAGGTTGTAGCAATCAAAGCTCCGGGGTTTGGGGACAATAGGAAGAACCAGCTTAA
AGATATGGCTATTGCTACTGGTGGTGTGGTCTTTGGAGAAGAAGGGTTGAATCTAAATCTTGAAGATGTTCAAGCTAAGA
CTTAGGAAAAGTTGTAGAGGTCATTGTCACCAAAGATGATGCCATGCTTTTGAAAGGAAAAGCTGACAAAGCTCACACTG
AAAAACGTACTCAAAAAATCACTGAGCATCTAGACATCACAACTGGTGATTATGAAAAGGAAAAGCTGGATGAGCGACTT
GCTAAAGTTTCAGATGGAGTAGCTGTGTTGAAGGTTGGAGGGACAAGTGATGTTGAAGTGACTGAAAAGAAAGAGTTACA
GACAGTCAGTCTCAAGGCTACAAGAGCAGCTGTTGAAGAAGGCATTGTTCTAGGAAGGGGCTGTGCTCTGCTTCGGTGCA
TCCCAGCCTTGGATTCATTAAACCCTGCTAATGAAGATCAGAAAATAGGTATAGAAATTATTTTAAAGCCCTCAAAATTC
CTGCAATGATGATTGCTAAGAATACAGGTGTTGGAGGATCTTTGATAGTTGAGAAAATTCTGCAGAGTTCCTCAGAAGTT
GGCTGTGGCACCATGCTTGGAGATTTTGTGAACATGGTGGAAAATGGAATCATTGATCCAACAAAGGTTGTGAGAACTGC
CTTATTGGATGCTGCTGGGGTGACCTCCTTGCTAAGTACAACCAAAGCTGTAAAGACAGAAATTCCTAAAGAAGAGAAGG
ACCCTGGAATGAGTGCAATGGATGAAATAGGAGGACTATGGGAGGTGGCATGTTC

ORF - retro_mmus_1225 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 84.04 %
Parental protein coverage: 77.84 %
Number of stop codons detected: 2
Number of frameshifts detected 5


Retrocopy - Parental Gene Alignment:

ParentalFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKG
F.KISKG.NPVEI.RGVMLA..A.IAELKK..KPV..PEEIAQVA.ISANGDKDIGNIISDAMKK.GRKG
RetrocopyFGKISKGVNPVEIQRGVMLAANAAIAELKK*FKPVIIPEEIAQVASISANGDKDIGNIISDAMKKAGRKG
ParentalVITVKDGKT-LNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANA
.ITVKDGKT.LNDELEI..G.KFDRGYISPYFINTSKGQ..EFQDAYVLL.EKKISSVQSIVPALEIAN.
RetrocopyAITVKDGKT>LNDELEITDGVKFDRGYISPYFINTSKGQNYEFQDAYVLLNEKKISSVQSIVPALEIANV
ParentalHRKPLVIIAEDVDGEALSTLV-LNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLE
H..PL.I.AE.VDGEALS.LV.LNRLKVGLQVVA.KAPGFGDNRKNQLKDMAIATGG.VFGEEGLNLNLE
RetrocopyHGSPLIIMAE*VDGEALSILV<LNRLKVGLQVVAIKAPGFGDNRKNQLKDMAIATGGVVFGEEGLNLNLE
ParentalDVQAH-DLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVL
DVQA..DLGKV.EVIVTKDDAMLLKGK.DKAH.EKR.Q.ITE.LDITT..YEKEKL.ERLAK.SDGVAVL
RetrocopyDVQAK<DLGKVVEVIVTKDDAMLLKGKADKAHTEKRTQKITEHLDITTGDYEKEKLDERLAKVSDGVAVL
ParentalKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIK-RALK
KVGGTSDVEV.EKK...T..L.ATRAAVEEGIVLG.GCALLRCIPALDSL.PANEDQKIGIEII...ALK
RetrocopyKVGGTSDVEVTEKKELQTVSLKATRAAVEEGIVLGRGCALLRCIPALDSLNPANEDQKIGIEIIL<KALK
ParentalIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAE
IPAM.IAKN.GV.GSLIVEKILQSSSEVG...MLGDFVNMVE.GIIDPTKVVRTALLDAAGV.SLL.T..
RetrocopyIPAMMIAKNTGVGGSLIVEKILQSSSEVGCGTMLGDFVNMVENGIIDPTKVVRTALLDAAGVTSLLSTTK
ParentalAVVTEIPKEEKDPGMGAMGGMGG-GMGGGMF
AV.TEIPKEEKDPGM.AM...GG..MGGGMF
RetrocopyAVKTEIPKEEKDPGMSAMDEIGG<TMGGGMF

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






RNA-Seq - click to see more details

(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
SRP007412_brain 0 .02 RPM 93 .17 RPM
SRP007412_cerebellum 0 .00 RPM 79 .33 RPM
SRP007412_heart 0 .09 RPM 210 .75 RPM
SRP007412_kidney 0 .04 RPM 298 .39 RPM
SRP007412_liver 0 .11 RPM 313 .50 RPM
SRP007412_testis 0 .00 RPM 22 .73 RPM

ChIP-Seq - click to see more details

RNA Polymerase II actvity near the 5' end of retro_mmus_1225 was not detected

EST - click to see more details

No EST(s) were mapped for retro_mmus_1225 retrocopy.

TSS - click to see more details

No TSS is located nearby retro_mmus_1225 retrocopy 5' end.

Lab - click to see more details

retro_mmus_1225 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_mmus_1225 has 0 orthologous retrocopies within eutheria group .

Parental genes homology:
Parental genes homology involve 18 parental genes, and 74 retrocopies.

Species Parental gene accession Retrocopies number
Ailuropoda melanoleuca ENSAMEG000000137701 retrocopy
retro_amel_771,
Canis familiaris ENSCAFG000000108654 retrocopies
retro_cfam_1185, retro_cfam_1620, retro_cfam_2165, retro_cfam_614,
Callithrix jacchus ENSCJAG000000039906 retrocopies
retro_cjac_1516, retro_cjac_1534, retro_cjac_1975, retro_cjac_3172, retro_cjac_3400, retro_cjac_4096,
Echinops telfairi ENSETEG000000091844 retrocopies
retro_etel_1440, retro_etel_426, retro_etel_885, retro_etel_925,
Homo sapiens ENSG000001443817 retrocopies
retro_hsap_1006, retro_hsap_2770, retro_hsap_2987, retro_hsap_3151, retro_hsap_3494, retro_hsap_3930, retro_hsap_4018,
Gorilla gorilla ENSGGOG000000082676 retrocopies
retro_ggor_1927, retro_ggor_2069, retro_ggor_2361, retro_ggor_2698, retro_ggor_800, retro_ggor_985,
Loxodonta africana ENSLAFG000000000531 retrocopy
retro_lafr_476,
Macropus eugenii ENSMEUG000000119872 retrocopies
retro_meug_1688, retro_meug_224,
Myotis lucifugus ENSMLUG000000008714 retrocopies
retro_mluc_1458, retro_mluc_2280, retro_mluc_2348, retro_mluc_601,
Macaca mulatta ENSMMUG000000104891 retrocopy
retro_mmul_83,
Monodelphis domestica ENSMODG000000122893 retrocopies
retro_mdom_427, retro_mdom_493, retro_mdom_756,
Mustela putorius furoENSMPUG000000078183 retrocopies
retro_mputfur_1118, retro_mputfur_245, retro_mputfur_434,
Mus musculus ENSMUSG00000025980 5 retrocopies
retro_mmus_1225 , retro_mmus_2494, retro_mmus_3206, retro_mmus_439, retro_mmus_706,
Nomascus leucogenys ENSNLEG000000068747 retrocopies
retro_nleu_1349, retro_nleu_2238, retro_nleu_229, retro_nleu_657, retro_nleu_675, retro_nleu_691, retro_nleu_787,
Otolemur garnettii ENSOGAG000000340535 retrocopies
retro_ogar_2335, retro_ogar_2420, retro_ogar_2740, retro_ogar_3221, retro_ogar_3497,
Pongo abelii ENSPPYG000000130465 retrocopies
retro_pabe_2040, retro_pabe_2244, retro_pabe_2476, retro_pabe_2887, retro_pabe_848,
Rattus norvegicus ENSRNOG000000145259 retrocopies
retro_rnor_1000, retro_rnor_1006, retro_rnor_1308, retro_rnor_1578, retro_rnor_1585, retro_rnor_2812, retro_rnor_2835, retro_rnor_596, retro_rnor_905,
Xenopus tropicalis ENSXETG000000075091 retrocopy
retro_xtro_63,


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