RetrogeneDB ID: retro_ptro_497

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 10:73333550..73333867(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: FAM32A
• Ensembl ID: ENSPTRG00000010641
• Aliases: None
• Description: family with sequence similarity 32, member A [Source:HGNC Symbol;Acc:24563]

Sequence

>retro_ptro_497
GCCTACAAGCAGGTCCAGAAGGGACCCCTGAAGCCGAAAGGCATCACAGAGCTTGGAGTGACCAAGCAGAAGAAGAAAAA
GAAGCACAAAGACAAGGCACAACTCAGGAAGAGATGGGAACAAGCAAAAAGAATGAGGAGAAGTGGTGCGGCCTGTTCAA
GCTGACCCTAGCCCAGGAGAAAGTGCAGGAGAAGCGACACATGGAAAGGATCCTGAAGAAAGCATCCCAGACCCACCAGC
AGAGAGAGGAGGACTTCAGCAGACACCTGGACGCACACACGGAGCATCGCGACACCCCCAAAGTCAGCTGGACCCAG

Alignment

ORF - retro_ptro_497 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 72.97 %
• Parental protein coverage: 98.21 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  AYEQVQKGPLKLKGVAELGVTKRKKKKKDKDKAKLL-EAMGTSKKNEEEKRRGLDKRTPAQAAFEKMQEK
          AY.QVQKGPLK.KG..ELGVTK.KKKKK.KDKA.L..E.MGTSKKNEE.K..GL.K.T.AQ...EK.QEK
Retrocopy AYKQVQKGPLKPKGITELGVTKQKKKKKHKDKAQLR<EEMGTSKKNEE-KWCGLFKLTLAQ---EKVQEK

Parental  RQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK
          R.MERILKKAS.TH.QR.EDF.RHLD..TEH.D.PKVSWT.
Retrocopy RHMERILKKASQTHQQREEDFSRHLDAHTEHRDTPKVSWTQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.02 RPM	49.30 RPM
SRP007412_cerebellum	0.00 RPM	41.48 RPM
SRP007412_heart	0.00 RPM	22.33 RPM
SRP007412_kidney	0.00 RPM	73.12 RPM
SRP007412_liver	0.00 RPM	56.99 RPM
SRP007412_testis	0.00 RPM	18.23 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_497 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_497 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_497 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_693
Gorilla gorilla	retro_ggor_592
Callithrix jacchus	retro_cjac_979

---

Parental genes homology:

Parental genes homology involve 16 parental genes, and 36 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000046846	1 retrocopy	retro_btau_312,
Callithrix jacchus	ENSCJAG00000014097	4 retrocopies	retro_cjac_15, retro_cjac_2459, retro_cjac_288, retro_cjac_979,
Homo sapiens	ENSG00000105058	4 retrocopies	retro_hsap_1116, retro_hsap_1950, retro_hsap_2541, retro_hsap_693,
Gorilla gorilla	ENSGGOG00000022418	4 retrocopies	retro_ggor_1420, retro_ggor_1587, retro_ggor_592, retro_ggor_872,
Loxodonta africana	ENSLAFG00000009394	1 retrocopy	retro_lafr_654,
Microcebus murinus	ENSMICG00000013721	3 retrocopies	retro_mmur_1449, retro_mmur_252, retro_mmur_500,
Myotis lucifugus	ENSMLUG00000000585	2 retrocopies	retro_mluc_2147, retro_mluc_59,
Monodelphis domestica	ENSMODG00000014904	1 retrocopy	retro_mdom_1401,
Mustela putorius furo	ENSMPUG00000016048	1 retrocopy	retro_mputfur_1493,
Mus musculus	ENSMUSG00000003039	2 retrocopies	retro_mmus_1612, retro_mmus_3017,
Nomascus leucogenys	ENSNLEG00000005441	3 retrocopies	retro_nleu_192, retro_nleu_2227, retro_nleu_2790,
Otolemur garnettii	ENSOGAG00000027763	2 retrocopies	retro_ogar_3348, retro_ogar_949,
Pan troglodytes	ENSPTRG00000010641	4 retrocopies	retro_ptro_1304, retro_ptro_1480, retro_ptro_497 , retro_ptro_684,
Rattus norvegicus	ENSRNOG00000039528	1 retrocopy	retro_rnor_105,
Sus scrofa	ENSSSCG00000013855	2 retrocopies	retro_sscr_292, retro_sscr_870,
Tarsius syrichta	ENSTSYG00000009106	1 retrocopy	retro_tsyr_418,